Gene Information

Name : serS (L150515)
Accession : NP_267868.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1767193 - 1768464 bp
Length : 1272 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATATTAAAAAAATTCGTGCTGATTTTGACGGTGTTGCTGCAAAATTAGCCACTCGTGGTGTTGAAAAAGAGAA
ACTTGAAAAACTTCATGACTTAGACATTAAACGTCGTGAACTCATTGTAAAATCTGAGGCTTTGAAAGCTGAACGTAATA
GTGTTTCTGATGAAATTTCTCAAGTAAAACGTGCAAAAGGCGATGCCAGCGCACAAATTGCTGCAATGCAAAAAGTTTCT
GCTGAAATCAAAGCCATTGATGCTGAACTTGCTGAAATCGAAGAAAACTTGAATGAAATCATTATCATGTTGCCAAATCT
TCCTCATGAAAGTACACCAATTGGTGCTGATGAAGATGATAATGTTGAGGTTCGTCGTGTTGGTCAAACTCCAACTTTCA
ATTTTGAACCTAAAGCTCACTGGGATTTGGGTGAAGATTTAGGAATTTTGGATTGGGAACGTGGTGGTAAAGTCACTGGT
TCACGCTTCCTTTTTTACAAAGGTGCTGGCGCAAGACTTGAACGTGCACTTTATAACTTCATGCTTGATGAGCACGGTAA
AGAAGGTTATACTGAAATGATTACTCCTTATATGGTTAATCAAGAGTCAATGTTTGGAACGGGTCAATATCCTAAATTTA
AAGAAGATACTTTTGAATTGAAAGATGACCGTGGTTTTGTTTTAATTCCAACTGCTGAAGTTCCTTTGACTAACTACTAT
CGTGGGGAAATTTTGGATGGCGCAGAATTGCCAATCAAATTCACAGCAATGAGTCCTTCTTTCCGTTCTGAAGCTGGTTC
TGCTGGTCGTGATACTCGTGGTTTGATTCGTTTGCACCAATTCCATAAAGTTGAAATGGTTAAATTTGCTAAACCTGACC
AATCTTATGATGAACTTGAAAAAATGACAGCAAACGCTGAAAATATTCTGCAAAAATTGGGTCTTGCATACCGTGTCGTG
GCTTTGTCAACTGGTGACATGGGATTCTCTGCTGCTAAAACTTATGATTTAGAAGTTTGGATTCCTGCACAAAATACTTA
CCGTGAAATTTCTTCATGTTCAAACTGTGAAGATTTCCAAGCCCGTCGTGCCCAAATTCGTTATCGTGACGAAGAGGGTA
AAGTTCAACTCCTTCACACTTTGAATGGTTCTGGACTTGCTGTTGGACGTACTGTGGCTGCTATTCTTGAAAATTATCAA
AATGAAGATGGCTCAATCACTGTTCCTGAAGTCCTTCGTCCTTATATGGGTGGACTTGAAGTAATTAAATAA

Protein sequence :
MLDIKKIRADFDGVAAKLATRGVEKEKLEKLHDLDIKRRELIVKSEALKAERNSVSDEISQVKRAKGDASAQIAAMQKVS
AEIKAIDAELAEIEENLNEIIIMLPNLPHESTPIGADEDDNVEVRRVGQTPTFNFEPKAHWDLGEDLGILDWERGGKVTG
SRFLFYKGAGARLERALYNFMLDEHGKEGYTEMITPYMVNQESMFGTGQYPKFKEDTFELKDDRGFVLIPTAEVPLTNYY
RGEILDGAELPIKFTAMSPSFRSEAGSAGRDTRGLIRLHQFHKVEMVKFAKPDQSYDELEKMTANAENILQKLGLAYRVV
ALSTGDMGFSAAKTYDLEVWIPAQNTYREISSCSNCEDFQARRAQIRYRDEEGKVQLLHTLNGSGLAVGRTVAAILENYQ
NEDGSITVPEVLRPYMGGLEVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-159 81