Gene Information

Name : tkt (L0043)
Accession : NP_267781.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1669206 - 1671182 bp
Length : 1977 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTTTGATACTACTGATCAATTGGCTGTAAATACGATTCGTACTCTATCATTAGATGCGATTCAAAAAGCAAATTCAGG
ACATCCTGGACTTCCAATGGGCTCTGCACCAATGGCTTATGTACTTTGGAGCAAATTTCTTAATGTGAACCCTAAGACAA
GTCGTAAATGGTCAAATCGTGACCGTTTTGTCTTGTCTGCTGGTCATGGTTCTGCAATGTTATATAGTTTATTACATTTG
GCAGGTTATAATGTAACGACTGATGATTTAAAAGGTTTCCGTCAATGGCAATCAAAAACACCGGGACATCCAGAAGTTAA
TCATACAGATGGTGTTGAAGCAACAACAGGTCCTTTAGGACAAGGAATTGCCAATGCTGTCGGAATGGCAATGGCTGAAG
CACATTTAGCAGCACAATACAATAAACCTGGTTTTGATATTGTTGACCATTACACTTACGCCTTAAATGGTGATGGTGAT
TTGATGGAAGGTGTTTCACAAGAAGCAGCTTCACTTGCAGGTAAATTGAAACTTGGTAAATTGATTCTTTTCTATGATTC
AAATAATATTTCTCTAGATGGTGACTTATCTATGTCATTTATTGATGATATTCAAAAACGTTTTGAATCATATGGCTGGC
AACATTTATTGGTAAAAGATGGAAATGATTTAGAAGAAATCGCAGCAGCTGTTGAAGTGGCTAAAGCTGAAAAATCTAAA
CCAACAATCATTGAAGTTAAAACAGTCATTGGTTTTGGTGCTGAAAAACAAGGAACTTCAGCAGTTCACGGAGCTCCTCT
TGGAGCTGAAGGTGTTGCATTTGCCAAGAAAGCATATGGTTGGGATTATCCTGAATTTACAGTTCCTGAAGAAGTATCAA
AACGCTTTTTAGAAACGACAGTTGCGCGTGGTGAAGCGATGGAGCAAGTATGGCGCAGTACTTTTGATGATTATTCTGAA
AAATACCCTGAGCTTGCTGAGCAATACGCAAAAGCTTTTGAAAATGAAACGCCAGAGCTTACTTTGACCAAGCATGAAAT
GGAAACAAGCAAGGCCAGCCGTGTAACTTCACAAGAAGCTATCCAAGAATTATCAGCTCAAATGCCAAATCTTTGGGGTG
GGTCTGCTGACCTTTCGGCTTCAAATAATACAATGGTTAAAGTTGAAGAAGACTTCATGCCAGATAACTATGCTGGACGT
AATATTTGGTTTGGTGTACGTGAATTTGCAATGGGAGCCATTATGAATGGGATTGCTTTGCATGGTGGAACTCGTGTCTA
TGGCGGAACATTCTTCGTCTTCTCAAACTACATGCTTCCTTCTGTTCGGATGGCTGCTCTACAAAGCTTACCAGTTACTT
ATGTTTGGACACATGATTCCATTGCTGTTGGGGAAGATGGTCCAACTCACGAACCTGTTGAACAATTAGCTTCTGTTCGC
TCAATTCCTAATTTGGATGTAATTCGTCCAGCTGATGGAAATGAAGTAGTGGCTGCATGGCGTCGTGCTGCATCAAGTAA
AAGCCGCCCAACCGCACTTATTTTGACTCGTCAAAATCTTCCAGTTTTACCTGATACTTATGAATTGGCTGAAGAAGGTC
TGAATCGTGGGGCTTATATTCTTTCAAAAGAAGAAGGAAAACTTGAAGGAATCATCATTGCGACTGGTTCAGAAGTAGCA
TTAGCTCTTGAAGCTAAGAAGACTTTGGGTTCTGGCATTCGTGTCGTTTCAATGCCTTCAATGAATATTTTTGACGAACA
AGAAGCAGCTTATCGCGAAGAAATTTTACCAAAAGATGTAAGACGTCGTTTAGCGATTGAAGCTGGTACAAGTTACGGAT
GGGGTAAATATGTTGGACTTGATGGTGCAACAGTTACAGTAGATACTTGGGGCGCTTCGGCACCAGCAAATATCGTTCTT
CCAGCTTACGGATTTACTGCTGAAAATGTAGTTAAAGCATACAAAGAGCTTGACTAA

Protein sequence :
MFDTTDQLAVNTIRTLSLDAIQKANSGHPGLPMGSAPMAYVLWSKFLNVNPKTSRKWSNRDRFVLSAGHGSAMLYSLLHL
AGYNVTTDDLKGFRQWQSKTPGHPEVNHTDGVEATTGPLGQGIANAVGMAMAEAHLAAQYNKPGFDIVDHYTYALNGDGD
LMEGVSQEAASLAGKLKLGKLILFYDSNNISLDGDLSMSFIDDIQKRFESYGWQHLLVKDGNDLEEIAAAVEVAKAEKSK
PTIIEVKTVIGFGAEKQGTSAVHGAPLGAEGVAFAKKAYGWDYPEFTVPEEVSKRFLETTVARGEAMEQVWRSTFDDYSE
KYPELAEQYAKAFENETPELTLTKHEMETSKASRVTSQEAIQELSAQMPNLWGGSADLSASNNTMVKVEEDFMPDNYAGR
NIWFGVREFAMGAIMNGIALHGGTRVYGGTFFVFSNYMLPSVRMAALQSLPVTYVWTHDSIAVGEDGPTHEPVEQLASVR
SIPNLDVIRPADGNEVVAAWRRAASSKSRPTALILTRQNLPVLPDTYELAEEGLNRGAYILSKEEGKLEGIIIATGSEVA
LALEAKKTLGSGIRVVSMPSMNIFDEQEAAYREEILPKDVRRRLAIEAGTSYGWGKYVGLDGATVTVDTWGASAPANIVL
PAYGFTAENVVKAYKELD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 4e-128 52
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 3e-130 49