Gene Information

Name : panE (L157055)
Accession : NP_267479.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : 2-dehydropantoate 2-reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG1893
EC number : 1.1.1.169
Position : 1357310 - 1358248 bp
Length : 939 bp
Strand : -
Note : ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis

DNA sequence :
ATGAGAATTACAATTGCCGGTGCAGGAGCGATGGGGAGTCGTTTTGGTTTAATGCTTCATAAAGGTGGCAATGAAGTAAC
CCTTATAGATGGATGGCCTGAACACGTTAAAGCGATTAAAGAGCATGGTTTGCGAGCTAATTACAATGGAGAAGAACTCA
CCGCTCATCTATCGGTTGAGTTACAATCTGAGATTTCTTCTAAAGAAAAAACAGATTTAATTATTTTGTTTACAAAAGCC
ATGCAATTAGATAAGATGCTACAAGATATTAAACCATTAATTGACGAGCATACCAAGGTACTTTGCTTACTAAATGGAAT
TGGTCACGAAGATACTATAGAAAAATATGTTTCGAAAAATAATATCTTTATTGGTAATACTATGTGGACTGCTGGATTAG
AAGGTCCAGGTAAAGCTAAATTATTTGGTGATGGTTCGGTTGAGCTACAAAATCTTATTTCAGGTGAGGAAGAAACAGCT
AAAAAGTTAGCAGAAATATTATCAGAATCGGGACTGAATGCTAAATATTCTAACAATATTCATTATTCTATTTATAGAAA
AGCTTGTGTTAATGGAACAATGAATGGGCTTTGTACTATTTTAGACACTAATATGGCCGGATTAGGTGAAACAAAACCAG
CACATGATATGGTTGTTACTATTGTTAATGAATTTGCAGCAGTAGCAAAATTTGAGAATGTAAACCTTGATATTGCTGAA
GTAGTTCAGCACGTTGAAACATGTTTTGATCCATCTACAATTGGATTACATTACCCTTCTATGTATCAGGATTTGATTAA
AAATAATCGATTGACAGAGATTGACTATATTAATGGGGCTGTTTCACGTAAAGGTAAAAAATATAATGTAGCCACACCTT
ATTGTGATTTCTTAACACAATTAGTTCACAGCAAAGAAGAGTTATTAAAAGCAAAATAA

Protein sequence :
MRITIAGAGAMGSRFGLMLHKGGNEVTLIDGWPEHVKAIKEHGLRANYNGEELTAHLSVELQSEISSKEKTDLIILFTKA
MQLDKMLQDIKPLIDEHTKVLCLLNGIGHEDTIEKYVSKNNIFIGNTMWTAGLEGPGKAKLFGDGSVELQNLISGEEETA
KKLAEILSESGLNAKYSNNIHYSIYRKACVNGTMNGLCTILDTNMAGLGETKPAHDMVVTIVNEFAAVAKFENVNLDIAE
VVQHVETCFDPSTIGLHYPSMYQDLIKNNRLTEIDYINGAVSRKGKKYNVATPYCDFLTQLVHSKEELLKAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0517 NP_814296.1 2-dehydropantoate 2-reductase Not tested Not named Protein 6e-124 81
ef0037 AAM75243.1 EF0037 Not tested Not named Protein 4e-124 81