Gene Information

Name : nrdE (L0294)
Accession : NP_267131.1
Strain : Lactococcus lactis IL1403
Genome accession: NC_002662
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1002635 - 1004803 bp
Length : 2169 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGTCTCTAAAACAACTTAAAGATGTAACTTATTTCAAGCTTAATAACGAGATTAATATTCCCGTTAATGGTAGCATTCC
TCTTGCTAAAGATAAAGAAGCAATTACTGCTTTTTTTAAAGAAAATGTCGAACCTAATCGTTATGAAGCCGATACATATA
TCGATAAACTCAATTGGCTCGTTAAAGAAGAATATCTAGAAGCTGAGTTTCTTGAAAAATATAAACCCGAATTTATTACC
AATCTTCGGAAAGAATTGAGTAAATTTGAATTTCATTTTGATTCATTTATGGCTGCTTACAAATTTTATAATCAATATGC
CATGAAAAACAATGACGGTTCTCTCTATCTTGAAGATTTTGAAGACCGTGTGTTAATGAATGCTTTATACATGGCTGACG
GCGATGAAAAATTAGCTAATAATCTTGCTTTTGCAATGATTAATCGTCGTTATCAACCTGCGACTCCGACTTTTCTAAAT
GCTGGACGTAAGCGTCGTGGTGAATTTGTTTCTTGTTTCCTTCTACAATTAACTGATGATATGAATTCAATTGGACGAAC
AATTAACTCTGCCTTGCAACTTTCTAAAAATGGTGGTGGTGTTGGTCTAAACTTGACTAATTTACGTGCTGCTGGTGCAC
CTATCAAAGGTTACGATGGAGTGGCAGCTGGTGTCGTTCCTGTCATGAAACTTTTTGAAGACGCCTTTTCTTATGCCAAT
CAATTGGGGCAACGTCAAGGTGCTGGTGTTGTTTATTTATCACTATTCCATCCAGATATTATGGAATTCTTGTCCACTAA
AAAAGAAAATGCGGATGAAAAAATTCGTGTTAAAACACTCTCTCTTGGGGTTACTGTTCCTGATAAATTCTATGAATTGG
TTAAAAAGGGAGAAACAATGTATCTCTTTGAGCCATATTTTGTTGAAAAATATTATGGTAAACCTTTTGCCGAAGTCGAT
ATTACAGCTGAATATGACAAAATGGTAGCCAATCCAGAAATTCGTAAAACATCGATTAATGCCCGTGAACTTGAACAAGA
ACTTTCAAAACTTCAACAAGAATCTGGTTATCCTTACATCGTAAATGTTGACACAGTCAATCAAGCTAACCCTGTTGATG
GTGTAATTTCAATGTCTAACCTTTGTTCTGAAATTTTGCAAGTCCAAACGCCTTCTGTTTTGAACGATGACCAAACTTAT
AAGGTGGTTGGAACTGACGTCGCTTGTAACTTGGGTTCAACTAATGTTTTGAATATGATGACTTCTAGCAATGAATTTGG
AACTTCTATTGAAGCAATGGTTCGCGCTTTAACTTTCATCTCCGAAACTTCAAACCTCGATACTGTTCCAACTGTTCGTA
AAGGTAATGATGAAATGCATGCGATTGGGCTTGGAGCAATGGGCTTACATTCTTTCTTAGCACAAAATCAAATTCATTAT
GACAGCAAAGAAGCCGTTGAATTTACTAGTGTTTATTTCATGTTGTTGAACTATTATACTTTAGTGGCTTCAAATAAATT
AGCTGTTGAAAAAGGGTCTAGCTTCAAGAATTTTGAAAAATCTGCCTATGCTGATGGTTCTTATTTTGATAAATATTTAA
CACATGATTATTTTGCAGCTGTCTCTTCTAAAGTTCAAGAACTTTTCAAAGGGATTGCTGTTCCAACAATCGAGGATTGG
ACTGCTTTACGTGACACAGTAAAAACTTCTGGACTCTATAATTCATACCGTATGGCTGTGGCTCCAAATGGTTCTATTTC
TTATATCAATGACTGTTCTTCTTCTATTCACCCAATTGTCAATCGCATCGAAGAACGTCAAGAAAAGAAAGTTGGGAAAA
TTTATTATCCAGCTGCTGGACTTGCCACTGAAACAATTCCTTATTACAAATCAGCTTATGATACAGATATGCGTGCAGTA
ATTGACGTTTATGCAGCTGCTACAGAACATGTTGACCAAGGTTTGTCACTCACTTTATTTATGCGTTCAACTTTACCTGA
AGGTCTCTATGAATGGAAAGTGGCAAATAATAAAATGACAACTCGTGACTTGTCTATTTTGCGTAACTATGCTTACAAAA
AAGGAATCAAAACAATTTACTACATTCGTACATTTACTGACGACCAAGAAGAAGTCGGTGCTAACCAATGTGAAAGTTGC
GTTATTTAA

Protein sequence :
MSLKQLKDVTYFKLNNEINIPVNGSIPLAKDKEAITAFFKENVEPNRYEADTYIDKLNWLVKEEYLEAEFLEKYKPEFIT
NLRKELSKFEFHFDSFMAAYKFYNQYAMKNNDGSLYLEDFEDRVLMNALYMADGDEKLANNLAFAMINRRYQPATPTFLN
AGRKRRGEFVSCFLLQLTDDMNSIGRTINSALQLSKNGGGVGLNLTNLRAAGAPIKGYDGVAAGVVPVMKLFEDAFSYAN
QLGQRQGAGVVYLSLFHPDIMEFLSTKKENADEKIRVKTLSLGVTVPDKFYELVKKGETMYLFEPYFVEKYYGKPFAEVD
ITAEYDKMVANPEIRKTSINARELEQELSKLQQESGYPYIVNVDTVNQANPVDGVISMSNLCSEILQVQTPSVLNDDQTY
KVVGTDVACNLGSTNVLNMMTSSNEFGTSIEAMVRALTFISETSNLDTVPTVRKGNDEMHAIGLGAMGLHSFLAQNQIHY
DSKEAVEFTSVYFMLLNYYTLVASNKLAVEKGSSFKNFEKSAYADGSYFDKYLTHDYFAAVSSKVQELFKGIAVPTIEDW
TALRDTVKTSGLYNSYRMAVAPNGSISYINDCSSSIHPIVNRIEERQEKKVGKIYYPAAGLATETIPYYKSAYDTDMRAV
IDVYAAATEHVDQGLSLTLFMRSTLPEGLYEWKVANNKMTTRDLSILRNYAYKKGIKTIYYIRTFTDDQEEVGANQCESC
VI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 3e-167 51