Gene Information

Name : pepA (Z5872)
Accession : NP_290893.1
Strain : Escherichia coli EDL933
Genome accession: NC_002655
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : 3.4.11.1
Position : 5370034 - 5371545 bp
Length : 1512 bp
Strand : -
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAGTTTAGTGTAAAAAGCGGTAGCCCGGAGAAACAGCGGAGTGCCTGCATCGTCGTGGGCGTCTTCGAACCACGTCG
CCTTTCTCCGATTGCAGAACAGCTCGATAAAATCAGCGATGGGTACATCAGCGCCCTGCTACGTCGGGGCGAACTGGAAG
GAAAACCGGGGCAGACATTGTTGCTGCACCATGTTCCGAATGTACTTTCCGAGCGAATTCTCCTTATTGGTTGCGGCAAA
GAACGTGAGCTGGATGAGCGTCAGTACAAGCAGGTTATTCAGAAAACCATTAATACGCTGAATGATACTGGCTCAATGGA
AGCGGTCTGCTTTCTGACTGAACTGCACGTTAAAGGCCGTAACAACTACTGGAAAGTGCGTCAGGCTGTCGAGACGGCAA
AAGAGACGCTCTACAGTTTCGATCAGCTGAAAACGAACAAGAGCGAACCGCGTCGTCCGCTGCGTAAGATGGTGTTCAAC
GTGCCGACCCGCCGTGAACTGACCAGCGGTGAGCGCGCGATCCAGCACGGTCTGGCGATTGCCGCCGGGATTAAAGCCGC
GAAAGATCTCGGTAATATGCCGCCGAATATCTGTAACGCCGCTTACCTCGCTTCACAAGCGCGCCAGCTGGCTGACAGCT
ACAGCAAGAATGTTATCACCCGCGTTATCGGCGAACAGCAGATGAAAGAGCTGGGGATGCATTCCTATCTGGCGGTCGGT
CAGGGTTCGCAAAACGAATCGCTGATGTCGGTGATTGAGTACAAAGGCAACGCGTCGGAAGATGCACGCCCAATCGTGCT
GGTGGGTAAAGGTTTAACCTTCGACTCCGGCGGTATCTCGATCAAGCCTTCAGAAGGCATGGATGAGATGAAGTACGATA
TGTGCGGTGCGGCAGCGGTTTACGGCGTGATGCGGATGGTCGCGGAGCTACAACTGCCGATTAACGTTATCGGCGTGTTG
GCAGGCTGCGAAAACATGCCTGGCGGACGAGCCTATCGTCCGGGCGATGTGTTAACCACCATGTCCGGTCAAACCGTTGA
AGTGCTGAATACCGACGCTGAAGGCCGCCTGGTACTGTGCGACGTGTTAACTTACGTTGAGCGTTTTGAGCCGGAAGCGG
TGATTGACGTGGCGACGCTGACCGGTGCCTGCGTGATCGCGCTGGGTCATCACATTACCGGTCTGATGGCGAACCATAAT
CCGCTGGCCCATGAACTGATTGCCGCGTCTGAACAATCCGGTGACCGCGCATGGCGCTTACCGCTGGGTGACGAGTATCA
GGAACAACTGGAGTCCAATTTTGCCGATATGGCGAACATTGGCGGTCGTCCTGGTGGGGCGATTACCGCAGGTTGCTTCC
TGTCACGCTTTACCCGTAAGTACAACTGGGCGCACCTGGATATTGCAGGAACCGCCTGGCGTTCTGGTAAAGCAAAAGGC
GCAACCGGTCGTCCGGTAGCGTTGCTGGCACAGTTCCTGTTGAACCGCGCTGGGTTTAACGGCGAAGAGTAA

Protein sequence :
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGK
ERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVG
QGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVL
AGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHN
PLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKG
ATGRPVALLAQFLLNRAGFNGEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-90 55
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-90 55