Gene Information

Name : ptxA (Z5804)
Accession : NP_290825.1
Strain : Escherichia coli EDL933
Genome accession: NC_002655
Putative virulence/resistance : Virulence
Product : PTS system L-ascorbate-specific transporter subunit IIA
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG1762
EC number : -
Position : 5305421 - 5305885 bp
Length : 465 bp
Strand : +
Note : involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake

DNA sequence :
ATGAAATTACGTGATTCGCTGGCTGAAAATAAATCCATCCGTCTGCAGGCTGAAGCAGAGACATGGCAGGAAGCGGTGAA
AATCGGCGTTGACCTGCTGGTGGCGGCAGATGTGGTAGAGCCGCGTTACTACCAGGCGATTCTGGATGGCGTTGAACAGT
TCGGTCCTTATTTCGTTATCGCTCCGGGCCTGGCAATGCCGCACGGGCGTCCGGAAGAGGGCGTTAAGAAAACCGGTTTC
TCTCTGGTAACGCTGAAAAAGCCGCTGGAGTTCAACCACGATGACAACGATCCGGTGGATATCCTCATCACCATGGCGGC
GGTCGATGCCAATACTCACCAGGAAGTGGGCATCATGCAGATCGTCAACCTGTTTGAAGATGAAGAGAATTTTGACCGTT
TACGCGCCTGCCGTACCGAGCAGGAAGTACTGGATCTCATTGACCGCACCAACGCGGCAGCTTAA

Protein sequence :
MKLRDSLAENKSIRLQAEAETWQEAVKIGVDLLVAADVVEPRYYQAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGF
SLVTLKKPLEFNHDDNDPVDILITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
M5005_Spy_0150 YP_281514.1 PTS system 3-keto-L-gulonate specific transporter subunit IIA Not tested Not named Protein 5e-35 43
ORF10 AAK27337.1 unknown Not tested PAI-I AL862 Protein 7e-25 41
vpeA ADD91727.1 putative PTS system-specific IIA component VpeA Virulence PAI-I AL862 Protein 7e-25 41