Gene Information

Name : Z4195 (Z4195)
Accession : NP_289428.1
Strain : Escherichia coli EDL933
Genome accession: NC_002655
Putative virulence/resistance : Virulence
Product : type III secretion apparatus protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4789
EC number : -
Position : 3796536 - 3798596 bp
Length : 2061 bp
Strand : -
Note : -

DNA sequence :
ATGTTTAACAAAGTTTTGGTAGGGTTAAGGAGTCATCCAGAATTAATAATTCTTGGATTAATGGTGATGATTATCGCCAT
GCTCATAATTCCATTGCCCACCTATTTAATCGACTTTTTGATTGGGCTTAACTTAACATTGGCAATACTTGTATTTTTAG
GATCATTCTATGTTGATAGGATCTTAAGCTTTTCTTCATTTCCATCAATCCTCCTTATCACAACGTTATTTCGTTTGGCG
CTGGCGATCAGTACCAGTCGACTTATACTTCTTGAGGCGGATGCTGGAGAAATTATAACGAGTTTTGGTGAGTTCGTTAT
TGGAGATAGCCTGGTAGTTGGTTTTGTTATTTTCTCCATTGTTACTATTGTTCAGTTTATCGTGATTACTAAAGGTTCGG
AACGTGTGGCTGAAGTTGCTGCCCGCTTTTCGCTTGACGGTATGCCAGGTAAACAAATGAGCATTGACGCCGATCTACGC
GCCGGGATCATTGATGCAGATTTAGCAAAAGAACGTCGTAGTGTATTAGAACGAGAGAGCCAGTTGTATGGTTCCTTTGA
TGGTGCGATGAAATTTATCAAAGGTGATGCTATTGCAAACATTATTATTATCTTTGTTAATATTATCGGTGGGCTATCAG
TAGGAGTAGGCCAAAATGGAATGGATTTCTCAACAGCGTTGACTGTCTACACAATTCTTACTGTCGGTGATGGTCTTGTT
TCTCAAATTCCAGCTTTATTAATTGCTATTAGCGCAGGATTTATCGTTACGCGCGTAAATGGCGATAGTGATAATATGGG
GCAAAATATAATGTCCCAGTTATTAAGTAATTCTTTTGTCATTGTTGTGACATGTGTCCTCGCGCTAAGTATTGGGTTGC
TTCCAGGTTTTCCCCTTCTAGTGTTTTTATGTTTGGCAGTAATCTTAGGAATTTACTTTTACTTTAAATTCAAAAAGAAA
GGGACTGAAGAAACGGTTGTTGAGGGAGATATTACCGTTGGGTTGGAACCCTATAATCAAGATGATGATATCTCATTAGG
TATCATTAATAAACTTGATCAGGTTATTACCGAAACGGTACCCTTGGTCTTGATTATGAATAGTGTACAGGCTAAAAAAT
ACACTGAAATCAATCTTGCTGATAGGATTCGTAGTCAGTTTTTTATTGAGTATGGTATCCGCATTCCCGGTATTGTCATT
CGTGAGGGGGAAGGTCTTAATGATGAAGATGTCATATTAATGCTAAATGAAGTCAGAGCTTCACAATTTAAAATTTATCA
TGATCTTGTCTTGTTGGTTGAATATTCAGATGAAGTGGTTTCGACTTTGATCAAGAAACCTGTCATTGTAAATAGTAATG
GTGAACAATATTATTGGGTTACGAAAAGTGATGCTCAAAAATTAACAAAAATTGGCTGTTATACTCGCACGGCCATGGAT
GAAATGTATAATCATTTATCTGTCTGTCTGGCTCATAATATTAATGAGTACTTTGGTATACAAGAAACAAAATATATTCT
TGATCAATTAGAGATGAAGTATTCTGATCTATTAAAAGAAATATTAAGATATATAACCGTGCAGCGCATTTCAGAGGTAA
TTCAGCGTCTGATCCAGGAGCGAATTTCAGTGCGCAATATGCGGTTAGTTATGGAGGCCTTAGCATTATGGAGCCCACGA
GAGAAAGATATAATCACACTCGTCGAGCATGTACGAGGTGCATTAGGTCGCTACATTTGCCATAAGTTTTCATATTCTGG
AGAAATTAAAGCAATTGTGATTTCGCCTGAAATAGAGGACAGAATCAGAGATGGTGTCAGGCCTACCGCTGGCGGTACTT
TTCTTAATCTCGATGCATCCGAAGCTGAGATGATTCTGGATAATTTTAAACTGGCACTTTCTGGAATCAATATTCCTATT
AAAGACATTATTTTACTGGGATCTGTGGATATTCGTCGTTTTATCAAAAAACTTATTGAATCTAGTTATCGAGACCTCGA
AGTACTTTCGTACGGGGAACTAACGGAAAATGTTCCCGTTAATATTCTGAAAACTATTTAG

Protein sequence :
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGALGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3731 NP_311758.1 EivA Not tested LIM Protein 0.0 100
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 65
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 65
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 65
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 65
invA AAS66860.1 InvA Not tested SSR-2 Protein 6e-155 56
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 1e-150 55
escV AAC31514.1 L0035 Virulence LEE Protein 3e-89 41
escV NP_290269.1 hypothetical protein Virulence LEE Protein 5e-89 41
escV ACU09459.1 EscV protein Virulence LEE Protein 3e-89 41
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 5e-89 41
escV AAC38382.1 EscV Virulence LEE Protein 4e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Z4195 NP_289428.1 type III secretion apparatus protein VFG0557 Protein 0.0 65
Z4195 NP_289428.1 type III secretion apparatus protein VFG1006 Protein 1e-171 61
Z4195 NP_289428.1 type III secretion apparatus protein VFG0064 Protein 4e-102 42
Z4195 NP_289428.1 type III secretion apparatus protein VFG0813 Protein 2e-89 41
Z4195 NP_289428.1 type III secretion apparatus protein VFG0729 Protein 2e-89 41