Gene Information

Name : smpB (Z3913)
Accession : NP_289172.1
Strain : Escherichia coli EDL933
Genome accession: NC_002655
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3544754 - 3545236 bp
Length : 483 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACGAAGAAAAAAGCACATAAACCTGGTTCAGCGACCATCGCGCTTAACAAGCGCGCCCGTCACGAATACTTTATTGA
AGAAGAGTTCGAAGCGGGACTTGCCCTGCAAGGCTGGGAAGTTAAATCCCTGCGCGCAGGAAAAGCCAATATTAGCGACA
GCTATGTCCTTCTGCGCGACGGAGAAGCGTTCCTGTTTGGCGCAAACATCACGCCAATGGCTGTGGCTTCTACGCATGTG
GTGTGCGATCCTACCCGTACCCGCAAGTTACTTCTCAACCAGCGCGAACTTGATTCGTTGTACGGTCGCGTCAATCGAGA
AGGCTATACCGTAGTGGCGCTCTCCCTGTACTGGAAAAATGCCTGGTGCAAAGTGAAAATSGGCGTCGCCAAAGGTAAGA
AACAGCACGATAAACGTTCAGATATCAAAGAACGCGAATGGCAGGTGGATAAAGCGCGTATCATGAAAAACGCCCACCGT
TAA

Protein sequence :
MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSLRAGKANISDSYVLLRDGEAFLFGANITPMAVASTHV
VCDPTRTRKLLLNQRELDSLYGRVNREGYTVVALSLYWKNAWCKVKXGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 1e-46 69
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-20 47
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-15 44