Gene Information

Name : pyk (TC_0609)
Accession : NP_296985.1
Strain : Chlamydia muridarum Nigg
Genome accession: NC_002620
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 728454 - 729899 bp
Length : 1446 bp
Strand : +
Note : identified by match to PFAM protein family HMM PF02887

DNA sequence :
ATGATCGCTAGAACAAAAATTATTTGTACAATAGGCCCTGCAACAAACACCCCAGAAATGCTTGAAAAACTTCTTGATGC
GGGGATGAATGTAGCGCGTCTTAACTTCAGTCATGGTACCCACGAAAGCCACGGCCGGACCATTGCTATTCTTAAGGAAC
TACGCGAAAAGCGCCAAGTCCCTTTAGCTATTATGTTGGATACAAAAGGACCAGAAATTCGTTTAGGCCAAGTAGAATCT
CCTATAAAAGTGAAGCCAGGAGACCGTCTCACTTTAACCAGTAAAGAAATTTTGGGATCCAAAGAAGCTGGAGTCACTCT
TTATCCTAGCTGCGTGTTCCCTTTCGTTCGCGAACGCGCTCCCGTCCTGATTGATGATGGATATATCCAAGCCGTAGTTG
TCAATGCTCAAGAGCATCTCATTGAGATAGAATTTCAGAATTCAGGAGAAATCAAGTCTAATAAATCACTTAGCATCAAA
GATATAGACGTAGCCCTCCCCTTCATGACAGAGAAGGATATCACGGATCTAAAATTCGGGGTCGAACAAGAACTTGACCT
TATCGCAGCATCTTTTGTCCGATGTAACGAAGACATCGATAGCATGCGTAAAGTTTTAGAAAACTTCGGCCGGCCAAATA
TGCCGATCATTGCCAAAATAGAAAATCATTTAGGGGTACAAAATTTCCAAGAAATAGCCAAAGCTTCTGATGGAATTATG
ATCGCACGAGGAGATCTCGGCATCGAATTATCTATCGTTGAAGTCCCTGCCTTACAAAAATTTATGGCTCGTGTGTCCAG
AGAAACAGGCCGTTTTTGTATCACCGCAACACAAATGCTCGAGTCAATGATTCGCAATCCCCTTCCTACACGAGCCGAAG
TTTCCGATGTAGCTAATGCTATCCACGATGGAACTTCCGCTGTGATGTTATCAGGAGAAACTGCTTCAGGAACTTATCCT
ATAGAAGCTGTAAAAACTATGCGCTCGATCATCCAAGAAACGGAAAAATCCTTTGATTACCAAGCCTTTTTCCAACTCAA
TGACAAAAATAGCGCTCTCAAAGTCTCTCCTTATCTTGAAGCAATAGGCGCTTCAGGGATCCAAATCGCTGAGAAAGCTT
CTGCTAAAGCGATTATTGTATACACCCAAACTGGGGGATCTCCCATGTTTCTTTCTAAATATCGTCCCTATCTCCCCATT
ATTGCCGTTACCCCAAACCGCAATGTATACTATCGCTTAGCAGTAGAATGGGGCGTATACCCTATGCTAACCTCAGAATC
TAACCGAACAGTTTGGCGCCACCAAGCTTGTGTCTATGGAGTAGAGAAAGGAATCCTTTCAAACTATGATAAAATTCTTG
TTTTTAGCCGAGGAGCAGGGATGCAGGACACGAATAACCTTACTCTGACTACTGTAAACGATGTTTTATCTCCTTCTCTT
GAATGA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVES
PIKVKPGDRLTLTSKEILGSKEAGVTLYPSCVFPFVRERAPVLIDDGYIQAVVVNAQEHLIEIEFQNSGEIKSNKSLSIK
DIDVALPFMTEKDITDLKFGVEQELDLIAASFVRCNEDIDSMRKVLENFGRPNMPIIAKIENHLGVQNFQEIAKASDGIM
IARGDLGIELSIVEVPALQKFMARVSRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIHDGTSAVMLSGETASGTYP
IEAVKTMRSIIQETEKSFDYQAFFQLNDKNSALKVSPYLEAIGASGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPI
IAVTPNRNVYYRLAVEWGVYPMLTSESNRTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVNDVLSPSL
E

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-65 44
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 4e-66 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 4e-66 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 4e-66 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk NP_296985.1 pyruvate kinase VFG0479 Protein 2e-66 44