Gene Information

Name : clpC (TC_0559)
Accession : NP_296935.1
Strain : Chlamydia muridarum Nigg
Genome accession: NC_002620
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 668059 - 670671 bp
Length : 2613 bp
Strand : +
Note : similar to SP:P32670, GB:U00006, PID:409787, GB:U00096, and PID:1790383; identified by sequence similarity; putative

DNA sequence :
ATGTCGTATATGCTGAAGAGTATTCCACCTCGCCATATTCAGGTTTTTATGTTTGAGAAGTTTACCAATCGCGCAAAGCA
AGTGATTAAGTTGGCGAAAAAAGAAGCTCAACGACTCAATCACAACTATCTAGGAACCGAGCACATCTTATTGGGATTAC
TAAAACTAGGCCAAGGAGTGGCTGTTAATGTATTACGCACTCTTGGCGTTGACTTCGACACAGCAAAAAACGAAGTAGAA
AGACTCATTGGGTATGGACCGGAGATCCAAGTGTATGGAGATCCAGCTCTAACAGGTAGAGTGAAAAAATCTTTTGAATC
AGCTAATGAAGAAGCCTCTATTTTAGAACACAACTATGTCGGAACAGAACATCTTTTACTCGGAATTCTCAATCAAGCTG
ATGGTGTGGCTCTGCAAGTTTTAGAAAACTTGCATATAGATCCTAAAGAAATCCGAAAGGAAATTTTAAAAGAGCTAGAA
ACGTTTAATTTGCAGCTCCCTCCTTCTTCCTCTATTACCCCAAGAAACACGAATAGTTCTTCGTCTTCCTCTTCAAAATC
TTCTTCTTTAGGAGGACATTCTTTAGGTGGGGATAAACCTGAAAAGCTTTCCGCTCTCAAAGCGTATGGATATGACCTAA
CAGAAATGTTCAAAGAGGCTCGTCTAGATCCCGTTATTGGTCGATCTGCAGAAGTCGAACGATTAATTTTGATCCTTTGT
CGTCGTAGAAAAAACAACCCAGTTTTAATTGGAGAAGCTGGTGTAGGTAAAACAGCTATCGTTGAAGGATTAGCCCAAAA
AATTGTCTCTGGAGAAGTTCCTGAAGCTCTTCGTAAAAAACGATTGATCACCTTAGATTTGGCTCTGATGATAGCTGGAA
CCAAATATCGAGGTCAATTTGAAGAACGAATCAAAGCAGTTATGGATGAAGTCCGTAAGCATGGCAATATTCTTCTTTTC
ATTGATGAGCTTCACACCATTGTTGGCGCAGGGGCTGCTGAAGGAGCGATAGATGCTTCCCATATTTTGAAACCAGCCTT
AGCTCGTGGAGAAATTCAGTGCATAGGGGCTACAACTCTAGATGAATATCGAAAACACATTGAAAAAGATGCTGCTTTGG
AACGTCGATTCCAAAAAATTGTTGTTCAACCACCCAGTGTTGATGAGACTGTAGAAATTCTTAGAGGCCTGAAGAAAAAA
TATGAAGAGCATCATAATGTCTTCATCACCGATGAAGCTCTCGTTGCTGCTGCTAAACTATCCGACCAATACGTTCACGG
TCGCTTTCTTCCCGACAAAGCTATTGACCTTTTAGATGAAGCTGGAGCTCGTGTACGTGTCAATACAATGGGGCAACCTT
CGGAGCTTTTACGTTTAGAAGCTGAAATAGAAAGCACCAAACAGGCTAAAGAACAGGCTATAGGAACTCAAGAATATGAG
AAAGCTGCCAGCCTTCGTGATGAAGAGAAAAAGCTTAGAGAAAAACTAAGCAACATGAAACAACAGTGGGAATCAAATAA
AGAAGAACATCAAGTTCCTGTTGATGAGGAAGCTGTTGCTCAAGTGGTTTCAGTACAAACTGGTATTCCTGCGGCTCGCT
TAACAGAAGCAGAAAGCGAAAAATTATTAATGCTAGAGAATACTCTACAAAAGAAAGTAATTGGCCAAGATCAAGCTGTT
GCTAGTATTTGTCGAGCTATTCGTCGTTCAAGAACTGGCATTAAAGATCCTAATAGACCTATGGGATCCTTCCTATTTCT
AGGTCCTACTGGAGTTGGGAAAACTTTGCTAGCTCAACAAATTGCTGTTGAAATGTTTGGAGGAGAAGATTCTCTTATCC
AAGTAGATATGTCCGAATATATGGAGAAGTTTGCTGCGACCAAAATGATGGGATCTCCTCCAGGATATGTAGGTCACGAA
GAAGGCGGACATTTGACAGAACAGGTTCGCCGTCGCCCTTATTGTGTTGTTCTCTTTGATGAAATTGAGAAAGCTCATCC
AGATATTATGGATCTTATGTTGCAGATTCTTGAACAGGGCCGTCTAACGGATTCCTTTGGACGCAAGATTGATTTCCGTA
ATACCATTATTATTATGACTTCCAATTTGGGAGCTGATTTAATTCGGAAGACTGGAGAGATAGGTTTTGGTCTTCGTTCC
CATATGGATTATGGAGTGATCAAAGAGAAAATAGATGCTGCAGTCAAAAAGCATCTAAAACCAGAATTTATCAACCGTCT
AGATGAAAGTGTTATCTTTAAACCTCTTGAGAAGGAAGCCCTTTCTGAAATTATTCATCTAGAAATTAATAAACTGGGAT
CTCGTCTACAAAACCACCAAATGGCTCTTAATATTCCTGATTCGGTGGTCTCATTCTTGGTAGATAAAGGACATTCTCCA
GAAATGGGCGCCCGACCATTAAGACGTGTAGTGGAGCAGTACTTGGAAGATCCTTTAGCAGAGATGCTATTGAAAGAGTC
GTGCCGACAAGAAGCAAGAAAATTATGCGCTCGCCTAATAGAAGAGCGTGTTATTTTCGAGCGGGAAGACGAAATTTCTG
CTTTAGCTGTAGAGGGGGATGGCCCCGCCTCTGTTACAGCTGATGAATCATAG

Protein sequence :
MSYMLKSIPPRHIQVFMFEKFTNRAKQVIKLAKKEAQRLNHNYLGTEHILLGLLKLGQGVAVNVLRTLGVDFDTAKNEVE
RLIGYGPEIQVYGDPALTGRVKKSFESANEEASILEHNYVGTEHLLLGILNQADGVALQVLENLHIDPKEIRKEILKELE
TFNLQLPPSSSITPRNTNSSSSSSSKSSSLGGHSLGGDKPEKLSALKAYGYDLTEMFKEARLDPVIGRSAEVERLILILC
RRRKNNPVLIGEAGVGKTAIVEGLAQKIVSGEVPEALRKKRLITLDLALMIAGTKYRGQFEERIKAVMDEVRKHGNILLF
IDELHTIVGAGAAEGAIDASHILKPALARGEIQCIGATTLDEYRKHIEKDAALERRFQKIVVQPPSVDETVEILRGLKKK
YEEHHNVFITDEALVAAAKLSDQYVHGRFLPDKAIDLLDEAGARVRVNTMGQPSELLRLEAEIESTKQAKEQAIGTQEYE
KAASLRDEEKKLREKLSNMKQQWESNKEEHQVPVDEEAVAQVVSVQTGIPAARLTEAESEKLLMLENTLQKKVIGQDQAV
ASICRAIRRSRTGIKDPNRPMGSFLFLGPTGVGKTLLAQQIAVEMFGGEDSLIQVDMSEYMEKFAATKMMGSPPGYVGHE
EGGHLTEQVRRRPYCVVLFDEIEKAHPDIMDLMLQILEQGRLTDSFGRKIDFRNTIIIMTSNLGADLIRKTGEIGFGLRS
HMDYGVIKEKIDAAVKKHLKPEFINRLDESVIFKPLEKEALSEIIHLEINKLGSRLQNHQMALNIPDSVVSFLVDKGHSP
EMGARPLRRVVEQYLEDPLAEMLLKESCRQEARKLCARLIEERVIFEREDEISALAVEGDGPASVTADES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-177 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC NP_296935.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0079 Protein 0.0 51
clpC NP_296935.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0080 Protein 6e-148 49