Gene Information

Name : Ta1435 (Ta1435)
Accession : NP_394889.1
Strain : Thermoplasma acidophilum DSM 1728
Genome accession: NC_002578
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 1484150 - 1485460 bp
Length : 1311 bp
Strand : -
Note : E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGTACGATGCAATAATAATAGGTTCCGGCCCGGGAGGCTATGCAGCGGCCATACGCCTGGGCCAGAGGCAGAAGAAGGT
CGCTCTCATCGAAAAGGACAAGATTGGCGGTGAATGCCTTAACTACGGCTGCATACCATCAAAAGCACTGATAGAACTCG
CAAACTCGATAAACTACCTCAGGGAGATGCCAGGCGTATCCCTGAACTATTCCATAGACATGAAGAAATGGCAGGAATGG
AAGTGGTCCATGATCAACAGGCTGACCGGCGGCGTGGAAACGCTCTGCAAGGGTTATGGCGTCGACGTCATAAGGGGCGA
AGCTTACATCGTTGACGCAACCCATGTTAAAATAGGGGAGAAGGTGATCGAGGGAAAGAACCTGGTCATAGCCACCGGTT
CCAAGCCGGTCAGGATAAAGGGCATCGACGATGTGATGTACAACAGGGAAGTGCTCGATCTCGATCACATACCGGAGTCA
ACGGCCATAATAGGCGGCGGCTACATAGGGGTTGAGATTGGGACGGCGCTTGCGAAGCTCGGATCCAAGGTGACAATAAT
TGAGATGATGCCCAGCATACTTCCCGGCACGGATCAGGAGCTTGTAAGGCATGTTGAGAGGAGGCTGTCCCAGCTCGGCG
TCCGAGTTATGACCGGCAAGAAGGTTCTGAACACGCAGCACGGCGATAAGATAAGGGTGAACATGGAGGGCGGAGAGTAC
GTAGAGGCCGAGAAGGTCCTCATGACCGTTGGAAGGGTACCCAATACGGAGGGATTCGGCCTCGAGAACTTGAAGCTGGA
GATGGACGGGCGCTTCATAAAGACGGACGCGCACAAGCGCACAAGCGTGCCGAACGTTTACGCCATAGGCGACGTGTCCG
GGCAGCCCATGCTTGCGCACAAGGCATATTACGACGCGGATATTGCTGCGGACAACATATGCGGCATGGACAGCGTAGTA
GAATACAGGGCCATGCCATACGTCATATACTCTGATCCTGAGATAGCGTACACCGGATCGAAGTCAGCGAAGTCAACCAG
ATTTCCGGTTGCAGCAAACGGGAGATCGCTTACCATGAACGAGAGCATCGGAACATTCAATATATACTACGATGAGAAGG
GCATCGTAACAGGTGCCGGCCTTGCCGCACCTCACGCAAGCGAGCTGATAAGCGAACTGTCCCTTGCGGTTGAATCCGGG
CTGATGGCAATGGACATAGGGCTGACCATACACCCGCATCCGACCGTCAGCGAGGGCGTCAAGGAGACTGCAGAAGAAGC
CTACGGAAAGCCCCTGCACTTCAAAATTTGA

Protein sequence :
MYDAIIIGSGPGGYAAAIRLGQRQKKVALIEKDKIGGECLNYGCIPSKALIELANSINYLREMPGVSLNYSIDMKKWQEW
KWSMINRLTGGVETLCKGYGVDVIRGEAYIVDATHVKIGEKVIEGKNLVIATGSKPVRIKGIDDVMYNREVLDLDHIPES
TAIIGGGYIGVEIGTALAKLGSKVTIIEMMPSILPGTDQELVRHVERRLSQLGVRVMTGKKVLNTQHGDKIRVNMEGGEY
VEAEKVLMTVGRVPNTEGFGLENLKLEMDGRFIKTDAHKRTSVPNVYAIGDVSGQPMLAHKAYYDADIAADNICGMDSVV
EYRAMPYVIYSDPEIAYTGSKSAKSTRFPVAANGRSLTMNESIGTFNIYYDEKGIVTGAGLAAPHASELISELSLAVESG
LMAMDIGLTIHPHPTVSEGVKETAEEAYGKPLHFKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 3e-64 42