Gene Information

Name : purA (Ta1367m)
Accession : NP_394823.1
Strain : Thermoplasma acidophilum DSM 1728
Genome accession: NC_002578
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 1414339 - 1415646 bp
Length : 1308 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGGTTGTACCTAATGGAGAGGGCGATAAGACTGCGGCTGTTGTGGGTCTGCAGTTTGGTGATGAGGGAAAGGGCAAGAT
AACCGATTATCTCAGCGGATCTTACGATGTTGTTGTTAGATTCAACGGTGGAACAAACGCTGGGCATACCGTGGTGACCG
ATGAAGGGACGTTCAAGTTCCATCTTCTCCCTTCAGGATCCCTGCGTACATCATATGTTGTGCTCGGCAGCGGCATGGTT
ATCGATCCGGTTGCGTTGATCCCTGAGATAGAGATAGTGAGAAAGATCAATCCGGCACTGAAAATTATAATCAGCAGAAA
CGCCCATGTTGTAACGAAGATGCACAGGCAGATCGATGTGGAAGAGGAGAAGATAAGATCGAGCCTGATGATAGGAACCA
CTGCACAGGGCATTGGCCCCACATACGAAGATAAGTACGCACGGACTGGGATAAGGATGGTCGACATCTCCGATATTGAC
CTGATCAAGGAGAAGATAGAAACCATGTACAGGATGCACTCCAACCTGTTAGCCAACACTGAATTTTCCAATCTGGCAAA
GAGAGAGGAAATGGCCAAGGAGATATACGAAGCTGGCATCAAGCTCACTGGATACCTTGACTATACGGAGGTAGCGATAG
ACAGGCTTTATTCCCAGGGAAAAAGAATACTGTTCGAAGGCGCTCAGGGCGTGTTCCTGGATCCAGATTTTGGGTTCTAT
CCCTTCGTCACATCATCGAACACCATAAGCGCTTCAGTTTACACAGGAACCGGCTTCTCTCTCAGGAAGGTCAACAGGAT
AATAGGAGTTGCAAAGGCGTACGTATCTAAGGTTGGGGAGGGGCCATTTCCCACCGAAATAACTGGCGACCTCGCCAAGC
AGCTCAGGGATCTCGGTGGCGAATACGGAACGACAACTGGTAGGCCGAGAAGGGTCGGATGGCTCGATCTGCCCATGCTG
AAATACGCAGTACGCATAGATGACGTGGATGAGATAGCCATAACAAAGGTTGATACATTGGGCATGCTTGACACGGTTAA
GGTTTGCAGACAGTATCTCATAGATGGGAAGCCTATAGATTATGTTCCCAGAGACATGAATACCATAAAGAAGATCGAAC
CCGTGTACGATGAGTTCGAGGGATGGGGTGCCATCTCAGATTCGATCAGCGGCAGGAAGATATCGATAGATCAGCTGCCA
TCAAAGCTGGTGAAATACATAAAGTACATTGAAGATCAGGTTGGAAAGCCCATCGGCATAATATCCATGGGGAAGGAAAG
GAACAGAACTGTGAGAATAATAAAATGA

Protein sequence :
MVVPNGEGDKTAAVVGLQFGDEGKGKITDYLSGSYDVVVRFNGGTNAGHTVVTDEGTFKFHLLPSGSLRTSYVVLGSGMV
IDPVALIPEIEIVRKINPALKIIISRNAHVVTKMHRQIDVEEEKIRSSLMIGTTAQGIGPTYEDKYARTGIRMVDISDID
LIKEKIETMYRMHSNLLANTEFSNLAKREEMAKEIYEAGIKLTGYLDYTEVAIDRLYSQGKRILFEGAQGVFLDPDFGFY
PFVTSSNTISASVYTGTGFSLRKVNRIIGVAKAYVSKVGEGPFPTEITGDLAKQLRDLGGEYGTTTGRPRRVGWLDLPML
KYAVRIDDVDEIAITKVDTLGMLDTVKVCRQYLIDGKPIDYVPRDMNTIKKIEPVYDEFEGWGAISDSISGRKISIDQLP
SKLVKYIKYIEDQVGKPIGIISMGKERNRTVRIIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 4e-75 42