Gene Information

Name : BH0744 (BH0744)
Accession : NP_241610.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Resistance
Product : cadmium-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 803333 - 805246 bp
Length : 1914 bp
Strand : +
Note : -

DNA sequence :
ATGTTTGTAGAAACAAAATCTTTGAAACAAACAAATCGAATGGATACGAGTTGGTTTGAAAAATTAAAGCCTCATGCTGA
GCTGTTAGCCGCTCTGTTTAGCGGCTTGCTCATTTCCATTGGATGGGTGTTGGAAAATCAGCAAATCATTCCTGTAGCTG
TTGCCGTCTATTTAGCTGCGTATGTGATCGGTGGGTATGCGAAGGCAAAGGAAGGCATTGAAGAAACAATTGCAAATAGA
GAATTGAATGTTGAAATGCTCATGATCTTTGCGGCGATTGGTTCCGCGGCAATTGGGTACTGGATCGAAGGAGCGATATT
AATCTTTATTTTCTCATTAAGCGGTGCGCTTGAAACGTACACAATGAACAAAAGCAATAATGAAATTTCGGCCTTGATGG
AATTACAGCCGGAGGAAGCGCTACGGGTGAGAAATGGGAGTGAGGAAAGAATTCCTGTTAGTCAGTTACTAGTCGGGGAT
GTCATTGTCATCAAACCAGGGGAACGGGTGCCTTCCGACGGAAAGATCATCGAAGGTCAGACAAGTCTTGACGAAGCGGC
GATTACAGGGGAATCCATCCCCGTTAGCAAGTCATTACACGACGAAGTATTTGCCGGAACGGTGAATGTGCGCGGAACGA
TTATGGTGGAAATTACGAAGCCGAATAGCGAGACCTTATTTCAAAAAATCATTCAATTAGTGCAAACGGCTCAAAGTGAG
AAATCGCCGTCACAGCAATTTATTGAACGATTTGAGGGGCCGTATGTAAAAACAGTTCTTGTGGCGGTCGGGCTCATGAT
GTTTGTGCCCCATTTTGCCTTTGGCTGGAGCTGGACGGAGACGTTTTACCGAGCGATGATTTTGCTTGTCGTGGCGTCCC
CTTGTGCGCTCGTAGCATCGATCATGCCAGCGACTTTATCGGCGATATCGAATGGTGCCCGAAAAGGGATATTACTAAAG
GGTGGTGTGCACCTTGAGAATCTTGGCCAGTTGAGAGCAATTGCGTTCGATAAAACAGGAACATTGACGAAAGGCACACC
AGAGGTGACCGATGTTATTGTTCGTGATGGAATGACGAAGGAGGAGCTACTCACCTATGTGGTGTCGATTGAAAAATATT
CAAACCATCCACTCGCTTCTGCCATTGTTCGCCATGCATCCACCTGTATGAACGATCAGCTAAAACCTGTAAACATGGAG
GATGTGGCTGGGTTCGGAGTCAGCGCGTATCTGAATGGTATATCCTGGAAGATCGGGAAGGCTGATTTCGTTGGCAAGGT
GGAAGCAGAGCAGTTTAAAGGCGGAGTCGCTACCCGGTTAGCTGAGGAAGGAAAAACAATCGTTTTTGCAAGAGACGAGC
AAGGAATAGCCGGAGTGATCGCTCTTAAGGACCAGGTTCGCAAAGACACGCTCGCGGCGATTCAACAATTGCAAAAAGCA
GGGATTCGCACGATCATGCTAACGGGAGACAGCGAAAAAACGGCGGCGGCCATTGCGAAGGAAAGTGGCATTGATACGTA
TGTTGCAGAATGTCTTCCAGAAACGAAGGTAGATGAAATGAAGAAACTAAAACAGGCATACGGCACTGTCGCGATGGTAG
GGGACGGGATTAATGATGCGCCTGCTTTGGCAACGGCTTCCGTCGGTATCGCCATGGGGGAAGGAACCGATGTGGCGCTA
GAGACGGCGGATGTAGTGCTCATGAAAAACCACTTGCCGCGAATCGCTGAAGCCATCCAACTTTCGAAAAAAATGAATCG
AATCGTGAAGCAAAACATCGTGTTCTCCATTGTGGTCATCCTTGCGTTAATTGCCTCGAACTTTATGCAGTTTCTGCACT
TGCCGATGGGAGTCATCGGGCATGAAGGAAGTACAATATTAGTCATTCTAAATGGGCTCAGGCTGTTACGATAA

Protein sequence :
MFVETKSLKQTNRMDTSWFEKLKPHAELLAALFSGLLISIGWVLENQQIIPVAVAVYLAAYVIGGYAKAKEGIEETIANR
ELNVEMLMIFAAIGSAAIGYWIEGAILIFIFSLSGALETYTMNKSNNEISALMELQPEEALRVRNGSEERIPVSQLLVGD
VIVIKPGERVPSDGKIIEGQTSLDEAAITGESIPVSKSLHDEVFAGTVNVRGTIMVEITKPNSETLFQKIIQLVQTAQSE
KSPSQQFIERFEGPYVKTVLVAVGLMMFVPHFAFGWSWTETFYRAMILLVVASPCALVASIMPATLSAISNGARKGILLK
GGVHLENLGQLRAIAFDKTGTLTKGTPEVTDVIVRDGMTKEELLTYVVSIEKYSNHPLASAIVRHASTCMNDQLKPVNME
DVAGFGVSAYLNGISWKIGKADFVGKVEAEQFKGGVATRLAEEGKTIVFARDEQGIAGVIALKDQVRKDTLAAIQQLQKA
GIRTIMLTGDSEKTAAAIAKESGIDTYVAECLPETKVDEMKKLKQAYGTVAMVGDGINDAPALATASVGIAMGEGTDVAL
ETADVVLMKNHLPRIAEAIQLSKKMNRIVKQNIVFSIVVILALIASNFMQFLHLPMGVIGHEGSTILVILNGLRLLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 1e-100 44
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 9e-101 44
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 2e-99 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 2e-102 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-102 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BH0744 NP_241610.1 cadmium-transporting ATPase BAC0092 Protein 1e-122 48
BH0744 NP_241610.1 cadmium-transporting ATPase BAC0124 Protein 4e-86 42