Gene Information

Name : dhaS (BH0539)
Accession : NP_241405.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Virulence
Product : NADP-dependent aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 573140 - 574636 bp
Length : 1497 bp
Strand : +
Note : -

DNA sequence : 
ATGCAAAAAATCTCAACAAACGATAGCAAATTAAATCCAAGGTTAGTGGCGTTTTTAAACGGTGGACCAAAGAAGCTATT
TATTAATGGGGAATGGGTTGATTCATTCTCTGGACAATCTTTTGAAACGATGAATCCAGCAACCGGAGAAACATTAGCTC
TCGTAGCAGAAGCTGGGTCAGAGGACATCGATTTTGCAGTGAAAGCGGCAAGGAAAGCGTTCGATGAAGGGCCTTGGTCT
AAAATGAGCGCAGCGGAAAGAAGTCGACTCATATACAAGCTGGCTGATTTGATTGAGGATCATAAAGAAGCGTTAGCTCA
GCTTGAGACGTTAGATAATGGTAAGCCAATTCGTGAGACGGCCAATGCTGATATTCCATTAGTAATTGAACACTTTCGTT
ACTTTGCAGGGTGGGCGACAAAAATTGTGGGCCAAACCATCCCTGTACAAGGCCATTATTTTAACTACACGCGCCATGAA
GCCATTGGCGTTGTGGGCCAAATCATTCCTTGGAATTTCCCGTTATTGATGGCTGCTTGGAAACTTGGTGCCGCTCTAGC
TACAGGTTGTACGGTTGTGTTAAAACCGGCAGAGCAGACTCCACTTTCCGCCTTATATTTAGGAGAATTGATCAATGAAG
CAGGTTTTCCAAAAGGGGTTGTGAACATTGTCCCTGGATTTGGGCATTCGGCTGGAACTCCCCTTGTGAATCACCCAGCT
GTAGATAAAGTGGCTTTTACAGGGTCGACTGATGTCGGAAAGTTAATTATGAAACAAGCGAGTGAATCATTAAAAAGAGT
AACGCTTGAACTTGGGGGCAAGTCACCAAATATCATTTTACCTGATGCTGATTTGTCAAAGGCCGTTCCTGGCTCACTTA
TGGGCATTATGTTCAATCAAGGCCAAGTGTGTTGCGCAGGAAGTCGTTTATATGTACAAAAGAAACAGTATGATCATGTC
GTTGCTGACCTGGTGTCGTTAACGAACGAGATTCAGCAAGGGGATGGATTATTAGAACAAACGACCATGGGACCTCTGAT
TTCAAATCAACAACAAAGTCGAGTGAAAAATTACATCGATCGTGGGGTTGAGGAAGGGGCAGAACTACTAACAGGTGGGA
ACATTCCGTATGATCAAGGGTATTTTGTCGCCCCAACCATTTTTGCTGACGTGGATCATTCCATGACGATCGCCAAGGAG
GAAATTTTTGGTCCAGTTGTAGCCGCAATGCCGTTTGATAGCATAGACGACCTAATTGATAAAGCCAACGATTCTGATTA
TGGACTAGCTGCCGGTGTTTGGACACAGGATATTAAAAAAGCACACTACATTGCCCACCGAATCAAGGCAGGGACCATTT
GGGTGAATTGCTACAATGTATTCGATGCCGCGAGCCCGTTTGGTGGTTACAAACAATCGGGGATTGGCCGGGAAATGGGG
AGCTATGCATTAGAAAATTATACTGAAGTGAAAAGTGTTTGGGTGAATATGGATTAA

Protein sequence : 
MQKISTNDSKLNPRLVAFLNGGPKKLFINGEWVDSFSGQSFETMNPATGETLALVAEAGSEDIDFAVKAARKAFDEGPWS
KMSAAERSRLIYKLADLIEDHKEALAQLETLDNGKPIRETANADIPLVIEHFRYFAGWATKIVGQTIPVQGHYFNYTRHE
AIGVVGQIIPWNFPLLMAAWKLGAALATGCTVVLKPAEQTPLSALYLGELINEAGFPKGVVNIVPGFGHSAGTPLVNHPA
VDKVAFTGSTDVGKLIMKQASESLKRVTLELGGKSPNIILPDADLSKAVPGSLMGIMFNQGQVCCAGSRLYVQKKQYDHV
VADLVSLTNEIQQGDGLLEQTTMGPLISNQQQSRVKNYIDRGVEEGAELLTGGNIPYDQGYFVAPTIFADVDHSMTIAKE
EIFGPVVAAMPFDSIDDLIDKANDSDYGLAAGVWTQDIKKAHYIAHRIKAGTIWVNCYNVFDAASPFGGYKQSGIGREMG
SYALENYTEVKSVWVNMD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 6e-96 47
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-99 46
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-99 46
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-99 46
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 7e-97 46
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-98 46
hpaE AAO17179.1 HpaE Not tested tcd island Protein 6e-82 44
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 4e-81 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
dhaS NP_241405.1 NADP-dependent aldehyde dehydrogenase VFG0082 Protein 2e-96 47