Gene Information

Name : mphB (BH0381)
Accession : NP_241247.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Resistance
Product : macrolide 2'-phosphotransferase
Function : -
COG functional category : R : General function prediction only
COG ID : COG3173
EC number : -
Position : 410919 - 411821 bp
Length : 903 bp
Strand : +
Note : -

DNA sequence : 
ATGAGCAAAACAAAAGAGCAAGTCGTTGAGCTGGCACAAAAGCACGGAATCACGATTCAGGAAGGTTCATTGATATTGAA
TGAATCCGGTCTCGATTTTCAAGTCGTATTTGCCTTAGATGTGAATGGCAAACGTTGGGTGTTACGCTTACCGCGGCGGG
AGGATGTCGTTCCTTCAACGGCTAAAGAAAAGAAAACATTAGAACTGATTGCCCCTCATCTTTCGGTGCAAGTGCCAAAC
TGGGAAGTGTACTCAGTGGAAATGATCGCGTATAAACAGTTAAAAGGGGTACCAGCAGCCACGATCGACCACGGGAAAAA
GGCGTACGTATGGGAAATGGACCACACGAACGTCTCTGATCGGTTTATCGACACACTTGCAAGCGGGATGGCATCCTTGC
ATCAGATCAAGCAGGATGAGGCAAGGCGTGCAGGCGTCCCCGCGGAACAAGCAACGGAGGCAAGGGAACGAATGAGCGTA
CGTATGGAAAAGGTGAAGTCGGAATTTGGCGTCAGTGAACCACTTTGGGCTCGCTGGCAAAAGTGGTTACACCACGATGC
TTTATGGCCAGCCGAAACAGGTCTCGTTCATGGGGATTTGCATGCGGGACATATTCTCATTGGCGAGCAAACGGAAGTGA
CAGGTTTTATCGATTGGACAGAGGCGCAAGTAACCGATCTATCGGAAGACTTTGTTCCCCATTATCGAATTTTTGGGGAG
GCAGCACTGAATCGGTTAATTGCCGCATATGAAGAGGCGGGTGGTTACGTTTGGCCTTCCATGAAGGAGCACGTGATCGA
ACGGGAGGCAGCCTTCCCTGTAGCGATAGCCGAGTTTGCTTTAAAATCAGGAATCGGTGAGTATAAGCGAATGGCAAAAG
AGGTCCTTGGGGTGGCTGAGTAA

Protein sequence : 
MSKTKEQVVELAQKHGITIQEGSLILNESGLDFQVVFALDVNGKRWVLRLPRREDVVPSTAKEKKTLELIAPHLSVQVPN
WEVYSVEMIAYKQLKGVPAATIDHGKKAYVWEMDHTNVSDRFIDTLASGMASLHQIKQDEARRAGVPAEQATEARERMSV
RMEKVKSEFGVSEPLWARWQKWLHHDALWPAETGLVHGDLHAGHILIGEQTEVTGFIDWTEAQVTDLSEDFVPHYRIFGE
AALNRLIAAYEEAGGYVWPSMKEHVIEREAAFPVAIAEFALKSGIGEYKRMAKEVLGVAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mphBM YP_254221.1 macrolide 2'-phosphotransferase II Not tested ¥ðSh1 Protein 3e-70 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mphB NP_241247.1 macrolide 2'-phosphotransferase D85892.gene.p01 Protein 7e-81 55
mphB NP_241247.1 macrolide 2'-phosphotransferase AB013298.gene.p01 Protein 3e-70 47
mphB NP_241247.1 macrolide 2'-phosphotransferase AB092817.1.orf0.gene Protein 3e-70 47
mphB NP_241247.1 macrolide 2'-phosphotransferase AF167161.gene.p01 Protein 1e-70 46