Gene Information

Name : BH4036 (BH4036)
Accession : NP_244904.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Resistance
Product : cadmium-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 4172840 - 4174963 bp
Length : 2124 bp
Strand : -
Note : -

DNA sequence :
ATGGCTGACCAAGCGACCGTTGAAGTGAAGAAAACAACCTACCGCGTTCAAGGGTTTTCTTGCGCTAATTGTGCCAATAC
ATTTGAGAAAAATGTAAAGGATTTACATGGGGTCGTCGAAGCCCAAGTGAACTTCGGGGCCTCAAAGCTTACTGTTTACG
GTGATGCCACAGTGGAAGACTTGGAACGTGCAGGGGCGTTTGAACATTTAAAGGTTCGTCCTGAAAACGAAAAGGCGATA
GAGACGAAGGAGCCGTTTTGGAAAGCATACGGCCACGTGATCGTTTCTGCCCTCTTGTTGCTAGTAGGTGTGGTCTCGTA
TTTTATGAAAGGAGAAAGGCATCTGTGGACTGTCTCTTTATTTGCCTCATCGATTGTTATTGGCGGGTACTCATTATTTA
AGGCAGGTTTCTATAACCTCATACGGCTTCGCTTTGACATGAAGACGTTAATGACGGTGGCTGTTATTGGGGCGGCGCTA
ATTGGCGAATGGCTGGAGGGGGCTGTCGTTGTGATCCTTTTCGCAATTAGTGAAGCGTTAGAGCGATTTTCTATGGATCG
GGCGCGCCAATCCATCCGCTCCCTTGTCGATATGGCGCCGAAAGAAGCGCTGGTTCGCCGTAACGGGGAAGAGCTGGTGA
TTCCGGTGGAAGCGATCGAAGTAGGGGACATCATGCTCATTAAACCAGGGCAAAAGCTTGCCATGGATGGCATTGTTCGC
TCTGGTCGCTCCTCGATGAACGAGGCGGCGATTACAGGAGAATCCGTACCTGTGGAAAAAATGGTCGGAGACGATGTGTT
TGCAGGGACGTTAAACGAAGAAGGCTTTTTAGAGGTAGAGGTTACGAAACGGGTCGAGGATACAACGCTTGCGAAAATCA
TTCACTTAGTGGAGGAGGCGCAAGGAGAGCGCGCTCCATCGCAAGCGTTTGTCGATATGTTTGCAAAATATTACACACCG
GCGATTATGGTGATTGCTGCTCTCGTAGCGACAGTACCGCCCCTTTTCTTTGCCGGAAGCTGGGAAACGTGGATTTACCA
AGGGCTAGCCGTGCTCGTCGTCGGCTGCCCGTGCGCTCTCGTCATTTCTACCCCTGTGTCGATTGTGACGGCCATTGGGA
ATGCAGCGCGTCACGGCATTCTCGTGAAGGGGGGCATCTACTTAGAAGAGGCGGCAAGACTGCGTGCCGTTGCCTTTGAT
AAAACCGGGACATTAACAAAAGGGAAACCTGCTGTCACCGATTATCAAGTATACGATGCTGACACGGATGGACGTGAGCT
GTTAGCAGCTGTTGCCGCTTTAGAATACCGCTCGCAGCACCCTCTTGCAGCGGCGGTCATGAAAAAAGCAGACGACGAAC
AGCTTTCCTATACAGACATGGAGGTTTCCGAGTTTTCTTCAATTACAGGAAAAGGGATTGCCGGCACAGTGAATGGAATC
GCTATTAACGTTGGAAAGCCTGCCTTGTTTGGCGAGTTACCTCCAGCTATTGAAGCGGATGTAGCTCGCTTGCAAGCAGC
TGGTAAAACGATCATGCTTATCGGAGCGGAGCAAAAGGTTCTCGCCTTACTCGCTGTCGCCGATGAAGTGAGAGAGGTGA
GCCGTACGGCTGTGGAGCGTCTTCATGCGCTTGGCATTACGAAGACGGTCATGCTCACAGGAGATAACCGCATGACGGCC
CGCGCCATTGGAAAGCAAGTCGGTGTAGCGGAAGTAGAGGCAGAGCTTTTGCCTGAAGATAAGCTCGGCTTTGTGAAGGG
CTTGAAGGAGGAGCACGGCCGTGTGGCCATGGTTGGGGACGGAGTGAACGATGCACCCGCGCTAGCCGCCTCTTCTGTCG
GTGTGGCGATGGGAGGAGCGGGCACCGATACAGCCCTTGAAACAGCCGATGTGGCTCTAATGGGGGACGACTTACGGAAG
CTACCGTTTTTAATCCGCCTTAGCCGAAAAGCATTGCTAATAATAAAAGAAAATATTGCTTTTTCTCTCGGAATAAAACT
CGTCGCCTTGTTCCTAGTTGCGCCGGGCTGGCTCACATTATGGATCGCCATCTTAGCCGACATGGGAGCGACACTGCTCG
TCACACTAAACGGATTACGACTGTTGCGAATGAAGGACGAATAA

Protein sequence :
MADQATVEVKKTTYRVQGFSCANCANTFEKNVKDLHGVVEAQVNFGASKLTVYGDATVEDLERAGAFEHLKVRPENEKAI
ETKEPFWKAYGHVIVSALLLLVGVVSYFMKGERHLWTVSLFASSIVIGGYSLFKAGFYNLIRLRFDMKTLMTVAVIGAAL
IGEWLEGAVVVILFAISEALERFSMDRARQSIRSLVDMAPKEALVRRNGEELVIPVEAIEVGDIMLIKPGQKLAMDGIVR
SGRSSMNEAAITGESVPVEKMVGDDVFAGTLNEEGFLEVEVTKRVEDTTLAKIIHLVEEAQGERAPSQAFVDMFAKYYTP
AIMVIAALVATVPPLFFAGSWETWIYQGLAVLVVGCPCALVISTPVSIVTAIGNAARHGILVKGGIYLEEAARLRAVAFD
KTGTLTKGKPAVTDYQVYDADTDGRELLAAVAALEYRSQHPLAAAVMKKADDEQLSYTDMEVSEFSSITGKGIAGTVNGI
AINVGKPALFGELPPAIEADVARLQAAGKTIMLIGAEQKVLALLAVADEVREVSRTAVERLHALGITKTVMLTGDNRMTA
RAIGKQVGVAEVEAELLPEDKLGFVKGLKEEHGRVAMVGDGVNDAPALAASSVGVAMGGAGTDTALETADVALMGDDLRK
LPFLIRLSRKALLIIKENIAFSLGIKLVALFLVAPGWLTLWIAILADMGATLLVTLNGLRLLRMKDE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 0.0 66
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 0.0 66
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 0.0 66

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
BH4036 NP_244904.1 cadmium-transporting ATPase BAC0298 Protein 1e-120 51
BH4036 NP_244904.1 cadmium-transporting ATPase BAC0100 Protein 5e-74 43
BH4036 NP_244904.1 cadmium-transporting ATPase BAC0092 Protein 3e-92 42
BH4036 NP_244904.1 cadmium-transporting ATPase BAC0124 Protein 3e-87 42