Gene Information

Name : BH4007 (BH4007)
Accession : NP_244875.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : rRNA large subunit methyltransferase
Function : -
COG functional category : S : Function unknown
COG ID : COG1576
EC number : -
Position : 4145465 - 4145944 bp
Length : 480 bp
Strand : -
Note : SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA

DNA sequence :
GTGAATATTTCGATTATTTCAGTTGGAAAATTAAAAGAAAAATACTTAAAGCAAGGAATCGCCGAATACACGAAACGCCT
CGGCGCCTACGCCAAGATCGAGCTCATCGAAGTCCCCGACGAAAAAGCCCCAGAGCAGCTCAGCGACACCGAAATGGAAC
ACGTCAAACAAAAAGAAGGCGAGCGCATCCTCGCCAAACTCCACCCCGACACCTATGTGATTGCCCTAGCCATCGAAGGA
AGCATGAAAAGTTCAGAAGAATTAGCCGATACTATGGATAGACTCGCCACTTATGGAAAGAGCAAGGTAGCCTTCGTCAT
CGGCGGCTCCCTCGGCCTCAGCGACGCCGTCCTCAAGCGCGCAGACGAAAAGCTCTCCTTTTCGAAGATGACCTTCCCCC
ATCGGCTCATGCGGTTGATCTTGTTGGAGCAGGTGTATCGGGCGTTTCGGATTAATAGGGGGGAACCGTACCACAAATAG

Protein sequence :
MNISIISVGKLKEKYLKQGIAEYTKRLGAYAKIELIEVPDEKAPEQLSDTEMEHVKQKEGERILAKLHPDTYVIALAIEG
SMKSSEELADTMDRLATYGKSKVAFVIGGSLGLSDAVLKRADEKLSFSKMTFPHRLMRLILLEQVYRAFRINRGEPYHK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orfX YP_251938.1 rRNA large subunit methyltransferase Not tested SCCmec Protein 5e-49 65
unnamed BAD24821.1 conserved hypothetical protein orfX Not tested Type-V SCCmec Protein 3e-48 64
orfX BAA86653.1 open reading frame X Not tested Type-I SCCmec Protein 3e-48 64
SE0023 NP_763578.1 rRNA large subunit methyltransferase Not tested SCCpbp4 Protein 3e-47 64
unnamed BAG06184.1 conserved hypothetical protein orfX Not tested Type-VII SCCmec Protein 3e-48 64
unnamed BAB47681.1 open reading frame X Not tested Type-III SCCmec Protein 3e-48 64
SERP2529 YP_190070.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 3e-47 64
unnamed BAC53844.1 open reading frame X Not tested SRImec-III and SCCmec-III region Protein 3e-48 64
SAR0024 YP_039501.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 4e-48 64
unnamed BAC57492.1 hypothetical protein Not tested Type-IIIinv SCCmec Protein 3e-48 64
SAV0024 NP_370548.1 rRNA large subunit methyltransferase Not tested Type-II SCCmec Protein 4e-48 64
unnamed BAB72121.1 hypothetical protein Not tested Type-IVa SCCmec Protein 3e-48 64
unnamed BAB72138.1 open reading frame X Not tested Type-IVb SCCmec Protein 3e-48 64
unnamed BAC67575.1 open reading frame X Not tested Type-IVc SCCmec Protein 3e-48 64
orfXhom BAB83497.1 open reading frame X Not tested SCC 12263 Protein 3e-43 64
unnamed BAA82243.1 orfX Not tested Type-II SCCmec Protein 3e-48 64
orfX AAL26648.1 unknown Not tested SCCcap1 Protein 3e-48 64
unnamed ACL99851.1 hypothetical protein Not tested Type-V SCCmec Protein 3e-31 63
SSP0026 YP_300116.1 rRNA large subunit methyltransferase Not tested SCC15305RM Protein 2e-46 63