Gene Information

Name : leuS (BH3281)
Accession : NP_244147.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 3403502 - 3405922 bp
Length : 2421 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGTCATTCTCACACCGAGAGATTGAATCGAAATGGCAAAAGTATTGGGAAGAGAACAAAACGTTTAAAACGGAAGAAGA
TGAAACGAGGGAAAAGTTTTATGCCCTTGATATGTTCCCATACCCATCAGGCGCGGGACTTCATGTCGGTCATCCGGAAG
GTTACACGGCAACCGATATTTTATCGCGGATGAAACGAATGCAAGGGTACAATGTGCTTCATCCGATGGGGTGGGATGCG
TTTGGCCTTCCAGCTGAGCAATATGCGATTGATACGGGGAACAGCCCAGCCGAGTTTACGGAAAAGAACATTAATACGTT
CCGCAGACAAATAAAATCCCTCGGTTTTTCGTATGATTGGGATCGGGAAGTGAATACAACAGATCCTGATTACTATAAAT
GGACTCAATGGATTTTCATTCAGCTTTACAACAAAGGACTAGCGTACATCGACGAAGTGGCGGTAAATTGGTGCCCAGCC
CTTGGAACCGTATTAGCGAATGAAGAGGTCATTGATGGCAAGAGTGAGCGTGGTGGACACCCTGTTGAGCGTCGTCCGAT
GAAGCAATGGATGCTGAAAATCACCGAATATGCTGATCGCTTACTGGAGGATTTAGAAGAGCTCGATTGGCCAGAAAGCA
TTAAAGATATGCAGCGCAATTGGATCGGTCGTTCGGAAGGAGCAGAAGTGACGTTTTCGGTCGACGGGCATGATGATACG
ATTACTGTCTTTACGACTCGTCCAGATACGTTGTTTGGCGCCACTTATATGGTGTTAGCACCTGAGCATAAGCTTGTGGA
TGCGATTACAACTAGCGAGCAAAAACAAGCGGTCGAATCGTATAAGAAAGAAGTCGCAACAAAGAGCGACTTGGAACGGA
CAGAGCTGGCGAAGGAAAAAACCGGAGTTTTTACTGGTGCGTACGCTATCAATCCGGTGAATGGCGAGAAGGTGCCAATT
TGGATCGCTGACTACGTTCTCGTTAGCTACGGGACTGGTGCAATTATGGCTGTTCCGGCTCACGACGAACGGGACTATGA
GTTTGCAAAAACATTTGATTTGCCTATCAAGGAAGTAGTATCAGGCGGCGTTATAGAACAGGAGGCTTATACAGGGGACG
GTCCTCATGTGAACTCTGAATTTTTGAACGGTCTCAGCAAAGAAGAGGCGATTGAGAAAATGATTCAGTGGCTTGAAGCT
GAGAAAAAAGGAACGAAGAAAGTCACATACCGTTTACGTGACTGGCTGTTCAGTCGGCAGCGTTATTGGGGAGAGCCGAT
CCCAGTGATTCATTGGGAAGACGGAACAATGTCCACTGTTCCTGAAGATGAGCTACCACTAGAACTTCCGAAAATGTCGG
AAATCAAACCTTCTGGGACAGGTGAATCACCACTCGCGAACGCAACGGATTGGCTTGAAGTGGTGGACCCGGTCACAGGG
AAAAAAGGTCGCCGTGAAACGAACACGATGCCGCAATGGGCTGGAAGTTGCTGGTATTACCTTCGTTACATCGACCCTGA
TAATGAGCGGATGATCGCCGACCCTGAAAAGCTGAAAAAATGGCTTCCTGTCGATATTTATATCGGTGGTGCTGAACACG
CAGTGCTTCACTTGTTATATGCCCGGTTCTGGCATAAAGTGTTGTACGATCTAGGGGTCGTACCGACGAAGGAGCCGTTC
CAAAAGCTTTACAACCAAGGAATGATCCTTGGTGAAAACAATGAAAAAATGAGTAAATCGAAGGGAAATGTCGTCAACCC
TGATGATATTATAGACAGTCACGGAGCCGATACGCTTCGCTTATATGAAATGTTCATGGGACCGCTCGATGCTTCGATTG
CATGGTCGACAACTGGATTAGATGGAGCGCGTCGTTTCCTTGATCGTGTATGGCGTTTGCTTGTAGACGAAAATACGGAA
GAGAAAAGTAGCAAAATTGTAAACGGAGAAGGTTCTCCAGAGCTTAAGCGCGCCTATCATCAAACGGTGAAAAAGGTGAC
GGAAGACTTTGAAGAGCTGCGGTTTAATGTAGGAATCTCTCAGTTGATGGTGTATGTGAATGAAGCATACAAGCAAGAAG
AGCTTCCGCTAGATCAGGCGGAAGGATTCGTGAAGCTATTATCCCCTGTTGCACCACATCTTGCCGAAGAGCTTTGGAGC
AAGCTCGGTCATGAGGGAACAATCGCCTATGAACCGTGGCCAACGTACGACGAAGCCTTTCTAGTGGAAGATGAGGTGGA
AATCGTCGTCCAGCATAACGGAAAAGTCCGAGCCAAAGTTGTTGTGGCAAAAGATGCGACGAAAGAGCAGATGGAAGAGG
CGGCACTTGCCAACGAACGGGTGAAAGAATCGATCGACGGAAAGACCGTACGAAAAGTGATCGTTGTTCCAGGTAAGCTT
GTCAATATTGTCGCTAACTAA

Protein sequence :
MSFSHREIESKWQKYWEENKTFKTEEDETREKFYALDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYNVLHPMGWDA
FGLPAEQYAIDTGNSPAEFTEKNINTFRRQIKSLGFSYDWDREVNTTDPDYYKWTQWIFIQLYNKGLAYIDEVAVNWCPA
LGTVLANEEVIDGKSERGGHPVERRPMKQWMLKITEYADRLLEDLEELDWPESIKDMQRNWIGRSEGAEVTFSVDGHDDT
ITVFTTRPDTLFGATYMVLAPEHKLVDAITTSEQKQAVESYKKEVATKSDLERTELAKEKTGVFTGAYAINPVNGEKVPI
WIADYVLVSYGTGAIMAVPAHDERDYEFAKTFDLPIKEVVSGGVIEQEAYTGDGPHVNSEFLNGLSKEEAIEKMIQWLEA
EKKGTKKVTYRLRDWLFSRQRYWGEPIPVIHWEDGTMSTVPEDELPLELPKMSEIKPSGTGESPLANATDWLEVVDPVTG
KKGRRETNTMPQWAGSCWYYLRYIDPDNERMIADPEKLKKWLPVDIYIGGAEHAVLHLLYARFWHKVLYDLGVVPTKEPF
QKLYNQGMILGENNEKMSKSKGNVVNPDDIIDSHGADTLRLYEMFMGPLDASIAWSTTGLDGARRFLDRVWRLLVDENTE
EKSSKIVNGEGSPELKRAYHQTVKKVTEDFEELRFNVGISQLMVYVNEAYKQEELPLDQAEGFVKLLSPVAPHLAEELWS
KLGHEGTIAYEPWPTYDEAFLVEDEVEIVVQHNGKVRAKVVVAKDATKEQMEEAALANERVKESIDGKTVRKVIVVPGKL
VNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68