Gene Information

Name : polA (BH3153)
Accession : NP_244019.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : DNA polymerase I
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0749
EC number : 2.7.7.7
Position : 3267208 - 3269838 bp
Length : 2631 bp
Strand : -
Note : has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair

DNA sequence :
TTGAAAAAACTAGTACTGATCGATGGAAATAGTATTGCGTATCGCGCATTTTTTGCATTGCCATTGCTTAATAACGATAA
AGGTGTTTATACGAATGCCGTGTATGGATTTACAATGATGCTGTTAAAGGTGTTGGAAGACGAAAAGCCAACTCACATGG
TTGTTGCTTTTGACGCGGGTAAGACCACATTTAGGCATGATACATATGATGCGTACAAAAGTGGAAGGCAAAAAACGCCG
CCAGAGCTTTCAGAGCAATTTCCGCTCATTCGCGAGCTCTTGGATGCGTTTAACATTGCCCGTGTTGAAGTGGAAAACTT
TGAAGCGGACGATCTCATCGGTACATTGGCAAAACAGGCGAGTCAAGAAAACTTTGAAGTGAAAATCTTTACCGGTGATA
AAGACTTGTTGCAAATCGTGTCTGACCATGTGACGGTCGCTTTGACGAGAAAAGGAATTACACAGATTGATGTCTATGAT
GAAAAAGGCATTGAAGAACGATATGGAATTACACCAGAGCAGATTATTGATATGAAAGGTCTCATGGGGGATAGTTCGGA
TAATATTCCGGGCGTTCCAGGCATCGGAGAAAAGACAGCGCTGAAATTGTTAAAGGAATATGGTTCGGTTGAAAAAGTAC
TAGAGTCCATCGACGAAATTTCAGGGAAAAAGATGAAGGAGCGACTGGAAGAACATCGTGACCAAGCCCTTATGAGCAAG
AAGTTGGCGACGATTTATCTGGAAGCCCCAGTGACGCTGGACGCAGATTCGTTTACGTTTGGTGAATATGATAAAAAAGA
AGTTGTGAAATTGTTCAAGGAGCTTGATTTTAACTCATTGCTCGACAAAGTCGATGCAGACGGAGAAGGGATTGAAAAGG
AAGAACTCCAGTCTTTGAACTATGAAACGCTTCGTGAGGTAAAAGAGGCGCATTTAGCGGATAAAGCTGCCCTTGTTGTG
GAAGTGTTGGATGAGAACTACCATCAAGGCGACATTTTAGGGCTGGCGATCGCCCATAACAATGGTTGCTATTACATTCC
AACAGATGAAGCTCTCCGATCGGAAGCGCTTATTCAATGGTTAAAGGATGAACGCAAGGAGAAGTGGTTGTTTGATGCGA
AGCGTGCGGTCGTTGCGTTAGGCTGGAAAAACATTGAACTAGCTGGTAGTACATTTGACTTGCAAATGGCCTCCTATTTA
TTAGACCCGTCCACATCGTTTCATGAAGTGAGCGATGTGACGAAACATCACCGTAAAGGTCACGTGCATGAAGATGAGGC
GGTTTATGGGAAAGGGGCTAAACGCCGGATTCCTGACGAGAAAGAGCTAGGAGAACACCTGGCGCGGAAAGCGGACGCGA
TTTTTCAATTAAAGGAGCACGTTGAAGAGAAGCTGAAAGAAAATGAGCAGCTAGGGTTGTTCAACGAATTGGAGATGCCG
CTTTCGGTCATTTTAGGACGAATGGAAACAACAGGTGTAAAAGTCGATGTTGAGCAGCTTGAGCAAATGGGTGAGGACTT
AAATGCTCGTCTTGAGGAGCTTGAGCAAACGATTCACGAATTAGCCGGTGTCTCATTTAATATTAACTCCCCTAAGCAAT
TGGGTGAAATTTTATTTGAGAAGTTACAGCTTCCAGTCATTAAAAAGACGAAGACAGGGTATTCAACGTCTGCTGATGTG
TTAGAGAAGCTAGCTGGGCAACACGAGATCATTGATCACATACTTCACTATCGGCAGCTCGGTAAGCTAAATTCTACGTA
TATTGACGGATTGCTGAAAGTTGTTCACAAGGGGACTGGGAAGGTTCATACCCGCTTCAATCAGGCTCTAACTCAAACCG
GTCGCTTAAGCTCGACAGATCCGAATTTACAAAACATCCCGATTCGCTTAGAGGAAGGACGTAAAATTCGCAAAGCCTTC
GTTCCATCGGAAAAGGACTGGTTCATTCTTGCTGCTGATTATTCGCAAATTGAATTGCGCGTCCTTGCCCATTTTGCCGA
AGATGAAAAGCTTATGGAAGCGTTCCGTGAAGATATGGATGTCCACACGAAAACGGCGATGGACGTATTTCATGTTAGCC
AGGAAGAAGTAACGTCCAACATGCGTCGCAGTGCGAAAGCGGTCAACTTCGGAATTGTGTATGGCATTAGCGATTATGGA
CTGAGCCAAAACCTTGGCATCACTAGGAAGGAAGCGGCAACGTTCATCGAGCGTTATTTTGCTAGCTACCCGAAGGTAAA
GGAGTACCTCGATCACGTCATCGATGAAGCTCGAGAGAAGGGTTATGTGACAACACTGTTGAAGCGCCGCCGTTATTTGC
CTGACTTAACGAGTCGCAATTTCAATCAACGTAGCTTTGCAGAGCGTACAGCCATGAACACACCGATCCAAGGAACAGCT
GCTGACATTATAAAGCAAGCGATGGTTCAGATGGCGAGTCGGATGGACGAAGAAGACTTGCAAAGCCGATTACTGTTGCA
AGTGCATGACGAATTAATTTTTGAGGTGCCGAAGGAAGAAGTGGCGCAAATGAAAGAGCTTGTGACTTCTGTTATGGAGC
AAGCTGTGGAATTACGCGTGCCCCTAAAGGTGGACGTGGCTTGCGGTGACACATGGTATGATGCAAAGTAA

Protein sequence :
MKKLVLIDGNSIAYRAFFALPLLNNDKGVYTNAVYGFTMMLLKVLEDEKPTHMVVAFDAGKTTFRHDTYDAYKSGRQKTP
PELSEQFPLIRELLDAFNIARVEVENFEADDLIGTLAKQASQENFEVKIFTGDKDLLQIVSDHVTVALTRKGITQIDVYD
EKGIEERYGITPEQIIDMKGLMGDSSDNIPGVPGIGEKTALKLLKEYGSVEKVLESIDEISGKKMKERLEEHRDQALMSK
KLATIYLEAPVTLDADSFTFGEYDKKEVVKLFKELDFNSLLDKVDADGEGIEKEELQSLNYETLREVKEAHLADKAALVV
EVLDENYHQGDILGLAIAHNNGCYYIPTDEALRSEALIQWLKDERKEKWLFDAKRAVVALGWKNIELAGSTFDLQMASYL
LDPSTSFHEVSDVTKHHRKGHVHEDEAVYGKGAKRRIPDEKELGEHLARKADAIFQLKEHVEEKLKENEQLGLFNELEMP
LSVILGRMETTGVKVDVEQLEQMGEDLNARLEELEQTIHELAGVSFNINSPKQLGEILFEKLQLPVIKKTKTGYSTSADV
LEKLAGQHEIIDHILHYRQLGKLNSTYIDGLLKVVHKGTGKVHTRFNQALTQTGRLSSTDPNLQNIPIRLEEGRKIRKAF
VPSEKDWFILAADYSQIELRVLAHFAEDEKLMEAFREDMDVHTKTAMDVFHVSQEEVTSNMRRSAKAVNFGIVYGISDYG
LSQNLGITRKEAATFIERYFASYPKVKEYLDHVIDEAREKGYVTTLLKRRRYLPDLTSRNFNQRSFAERTAMNTPIQGTA
ADIIKQAMVQMASRMDEEDLQSRLLLQVHDELIFEVPKEEVAQMKELVTSVMEQAVELRVPLKVDVACGDTWYDAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
polA YP_281523.1 DNA polymerase I Not tested Not named Protein 0.0 49