Gene Information

Name : hemC (BH3046)
Accession : NP_243912.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3162348 - 3163283 bp
Length : 936 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGCGAAAAATAATTATCGGTTCAAGACGGAGCCAATTGGCGCTTACCCAAACGGAGTGGGTGATCAGCAAATTAAAAGA
GGCCGGTGCTCCTTTTGATTTTGAAATAAAAAAAATTATCACAAAAGGCGATCAAATTCTTGACGTTACCCTCTCAAAGG
TAGGGGGGAAAGGGTTATTTGTTAAGGAGATCGAACAGGCGATGGCGAACAAAGAAATCGATATCGCCGTTCACAGTATG
AAGGACGTTCCTTCTGTACTTCAGGAAGGATTTGCTCTAGGAGCAACAACGACTCGAGTCGACCCAAGGGATGCGCTCAT
TTCAAATGAAGGATATACGTTGGCCGAATTGCCAGCCGGTTCAATTGTCGGAACGAGCAGCTTACGACGCTCCGCCCAAA
TTTTAGCGAAGCGTCCAGACCTAGAAGTTAAGTGGATTCGTGGAAACATTGAAACACGCTTGCGAAAGCTAAAAGAGGAA
GATTTCGATGCGATCATTCTTGCCGCAGCAGGTCTTGAGAGAATGGGCTGGTCCAATGAAATTGTGACCGAATATCTTGA
CCCAGACCTTTGTGTTCCTGCGGTTGGACAAGGAGCTTTAGGCATTGAGTGCCGAGCGGATGACGACGAAGTTCTTGAGA
TGTTAAAGACGATCAATGATGACACAACGGCAAAGACGGTTCTAGCGGAGCGAACATTCCTTCATCGGATGGAAGGGGGA
TGTCAAGTTCCGATCGCTGGATACGCCACGTTAACAGATGAAGGAGAGATTGAGCTAACCGCCCTAGTCGGCACACCAGA
TGGTGAGCAAATTTTTAAAGAAATTCTTCGTGGAAAAGATCCTGTTCAACTTGGTGAAACGATGGCACAGGCTTTGATGG
ATCAAGGAGCGAAGGAAGTGCTAGAACAAGTGAAAAAAGGGTTGGAGTCGCAATGA

Protein sequence :
MRKIIIGSRRSQLALTQTEWVISKLKEAGAPFDFEIKKIITKGDQILDVTLSKVGGKGLFVKEIEQAMANKEIDIAVHSM
KDVPSVLQEGFALGATTTRVDPRDALISNEGYTLAELPAGSIVGTSSLRRSAQILAKRPDLEVKWIRGNIETRLRKLKEE
DFDAIILAAAGLERMGWSNEIVTEYLDPDLCVPAVGQGALGIECRADDDEVLEMLKTINDDTTAKTVLAERTFLHRMEGG
CQVPIAGYATLTDEGEIELTALVGTPDGEQIFKEILRGKDPVQLGETMAQALMDQGAKEVLEQVKKGLESQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-63 50
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-63 50