Gene Information

Name : serS (BH0024)
Accession : NP_240890.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 34678 - 35955 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTGGATATTAAACGGCTGCGAAAAGACTTTGCAGGAATTAGGGAAAAGTTGCAAACACGTGGTGAGGACATTTCAGG
CCTCGAAAAGTTTGGTAGCCTAGATGAAAAAAGGCGGCAAGTGATTGTAAAGGTAGAAGAATTAAAAAGCCGTCGTAACC
AAGTATCACAAGAGGTCGCTCAGCTTAAACGGGAAAAGAAAGACGCAGATCATCTCATTAAAGAAATGCGTGACGTTTCT
GATGAGATTAAAGGGTTAGATGAAACATTGCGTCAACTTGATGAAGAGCTTGATCAACTATTGCTTGCGATTCCAAATGT
CCCCCACGAAAGCACTCCTGTTGGAGAAACGGAAGATGACAACGTCGAAGTGCGTAAATGGGGGGAAGTGCCGAACTTTC
CTTTTGAACCGAAAGCCCATTGGGATCTAGCCACAGCATTAGGTATTGTTGATTTTGAGCGTGCCGCGAAAGTCACAGGA
AGCCGTTTTGCCTTCTATAAAGGGGCAGGAGCGCGGTTAGAGCGTGCGCTTATTAACTTTATGATGGATCTCCATCACGA
CAAGCACGGCTATGAGGAGGTTCTTCCGCCATACCTCGTCAATCGTACGAGCATGACTGGAACGGGACAATTACCGAAGT
TTGAAGAGGACGCCTTTAAAATTCGCGAGGAGGATTATTTCCTCATTCCGACAGCAGAAGTCCCAGTGACCAACTTGCAT
CGAGACGAAATTTTATCTGCGGATCAGCTACCGATCGCTTACACGGCATACAGCATGAATTTCCGTTCTGAAGCAGGCTC
TGCTGGGCGCGATACCCGTGGACTGATCAGGCAGCACCAATTTAATAAAGTCGAACTCGTTCGATTTGTAGCACCTGAAG
ATTCTTATGATGAACTTGAAAAGCTCACAGGCCATGCCGAAAAGGTGTTGCAGCTTCTGAAGCTTCCATATCGGGTGATG
AGCATGTGTACGGCTGATCTCGGCTTTACAGCGGCGAAAAAGTATGACTTAGAAGTATGGATTCCGAGCGCAAACACGTA
TCGGGAAATTTCTTCTTGCAGTAACTTTGAAGACTTCCAAGCGCGCAGAGCCAACATTAAATTCCGTCGAGAGGCGAAAG
GCAAAGCTGAGTTCGTTCACACATTAAACGGTTCTGGCCTTGCTGTTGGCCGTACGGTGGCAGCGATTTTGGAAAACTAT
CAACAGGAAGACGGAACGATTGTCATTCCAGAAGTGCTTCGCCCGTATATGGGTGGGATGGAAAAGTTTGAGGCGTAG

Protein sequence :
MLDIKRLRKDFAGIREKLQTRGEDISGLEKFGSLDEKRRQVIVKVEELKSRRNQVSQEVAQLKREKKDADHLIKEMRDVS
DEIKGLDETLRQLDEELDQLLLAIPNVPHESTPVGETEDDNVEVRKWGEVPNFPFEPKAHWDLATALGIVDFERAAKVTG
SRFAFYKGAGARLERALINFMMDLHHDKHGYEEVLPPYLVNRTSMTGTGQLPKFEEDAFKIREEDYFLIPTAEVPVTNLH
RDEILSADQLPIAYTAYSMNFRSEAGSAGRDTRGLIRQHQFNKVELVRFVAPEDSYDELEKLTGHAEKVLQLLKLPYRVM
SMCTADLGFTAAKKYDLEVWIPSANTYREISSCSNFEDFQARRANIKFRREAKGKAEFVHTLNGSGLAVGRTVAAILENY
QQEDGTIVIPEVLRPYMGGMEKFEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-129 64