Gene Information

Name : metC (BH1628)
Accession : NP_242494.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 1701372 - 1702544 bp
Length : 1173 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
GTGAGCGAACAGTACAGCTTGCAAACAAAACTACTTCATAATGAGCATAAGGTTGACCAGGCAACTGGTGCGGTAAGCGT
ACCAATCCAACACGCTTCTACGTTTCATCAGTTTGACTTTGATACGTTTGGAACGTATGACTATAGCCGTTCGGGTAATC
CGACACGGGATGCTCTCGAAGCGGCGATTGCTGAGCTTGAGGGAGGCAATCATGGATTTGCGTTTGCTTCTGGGATGGCT
GCCATCTCCACAGCGTTTATGCTTCTATCAAAGGGCGATCATGTTGTTTTAACGAAAGATGTGTACGGTGGGACATTTCG
CCTTGTAACGGAAGTTTTAACCCGACTTGGAATTGAACATACATTTGTTGATATGACAAACTTGGCAGAAGTGGCGGCGG
CCATCAGACCAAATACCCGTGTCCTTTATATGGAGACGCCATCCAATCCAACGTTGAACATTACCGACATTCGCGGGGTC
GTTTCGCTGGCAAAAGAACACGAATGTCTCACATTTCTTGACAACACCTTTTTAACACCAGCTTTGCAGCGACCGCTAGA
ACTTGGTGTCGATGTTGTCCTCCATAGTGCGACGAAGTTTATTGGAGGTCACAGTGATGTTGTCGCAGGGCTGGCGGTGA
CGAAGAATGAAGAACTCGGAAAAAAGCTCGCCTTTTTACAAAACTCGTTCGGCGCTATTTTAGGAGTTCAAGACGTATGG
CTCGTTCTCCGAGGTCTGAAAACACTTCATGTGCGGATGGAGCACGGAGAGAAAGGAGCTCAGCAGATCGCCGAATGGCT
TCAAGGCGTTCCGGAAGTGAAGCGGGTCTACTACCCTGGTTTAAAAGATCACCCAGGACACGAATTGCAAAAAAGGCAGG
CGGAAGGGTTTGGCGCTGTGCTATCGTTTGAGCTAGAAAATGAAGAGGCGGTTCGAAGGTTCGTGGAACATGTAAAGCTC
CCTGTTTTTGCTGTCAGTTTAGGAGCGGTAGAATCGATCTTGTCTTACCCCGCCAAAATGTCCCATGCCGCGATGCCGAA
AGAGGAGCGGGAGGCAAGAGGCATTCGTGATGGATTGCTTAGACTTTCAGTCGGGTTAGAAAAACCGGAAGAACTAATGG
CTGACTTTAAAGCGGCATTTGCTCACGTTCGAGGAAAGGTGGAACATCTATGA

Protein sequence :
MSEQYSLQTKLLHNEHKVDQATGAVSVPIQHASTFHQFDFDTFGTYDYSRSGNPTRDALEAAIAELEGGNHGFAFASGMA
AISTAFMLLSKGDHVVLTKDVYGGTFRLVTEVLTRLGIEHTFVDMTNLAEVAAAIRPNTRVLYMETPSNPTLNITDIRGV
VSLAKEHECLTFLDNTFLTPALQRPLELGVDVVLHSATKFIGGHSDVVAGLAVTKNEELGKKLAFLQNSFGAILGVQDVW
LVLRGLKTLHVRMEHGEKGAQQIAEWLQGVPEVKRVYYPGLKDHPGHELQKRQAEGFGAVLSFELENEEAVRRFVEHVKL
PVFAVSLGAVESILSYPAKMSHAAMPKEEREARGIRDGLLRLSVGLEKPEELMADFKAAFAHVRGKVEHL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-84 53
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-84 50
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-86 50