Gene Information

Name : metB (BH1627)
Accession : NP_242493.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Unknown
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1700239 - 1701375 bp
Length : 1137 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGAATCGTAAAGAATTAGAAACAGCTTTAGTACAAATCGGAAATCGAATGGATGATCGAACAGGTGCGATCAACACGCC
TGTTTACTTTTCGACCGCCTATCGTCACTCCGGAATTGGCGAATCCACTGGCTATGACTATGCACGGACAGGGAATCCCA
CGAGAGAAGTGCTTGAAAAGGCGATTGCTACGTTAGAAAACGGAGATCAAGGGTTTGCCTGTAGTTCCGGTATGGCAGCT
ATCCAAACGGTGTTTTCTCTTTTTCAATCAGGGGATGAAATTATTGCTTCCCAAGATTTGTATGGAGGAACGTACCGCTT
GTTTGAAGGTGGCTGGAAAAAGTGGGGGCTTTCTTTCTCCTATGCTGATCCGCGAAATCTTGCAGCGTTAGAACAGCAAA
TAACAGAAAAAACGAGGGCGCTGTTTATTGAAACCCCTACGAATCCACTCATGCAAGAAGCAAATATTCGTGAGCTTGCC
GCCCTTGCTAATAAACATGGGTTGCTGCTGATCGTCGATAATACGTTCTATACGCCACTTTTACAACAACCATTAAACGA
AGGGACCCATATCGTCATCCATAGTGCGTCAAAATACTTAGGCGGACACAATGATGTCATCGCTGGATTGATTGTTGCCA
AAGGACAAGAGCTATGTGAGCAGATCGCCTATTACCATAACGGAATTGGCGGAACGCTCTCAGCCTTTGATTCATGGTTG
CTCATTCGTGGGATGAAAACTCTTGCTCTACGAATGGAGCAGCATCAAAACAATGCGAGGGCTATAGCGTCTTACTTAGA
AAAGCATGAAGGAGTAACGGATGTTCTTTATCCTGGACGGGGTGGGATGCTTTCCTTCCGCATCCAATCGGAGAGCTGGG
TTAACCCGTTTTTACAATCGTTGAAGCTCATTTCATTTGCAGAGAGCCTAGGGGGAGTCGAGAGCTTAATGACCTATCCG
GCGACGCAAACCCATGCCGATATTCCAGAGGATGTGCGGATCGCTAACGGTGTATGTAATCGCTTGTTGCGATTCTCAGT
TGGGATCGAACATGTGGGTGATTTGATTGCCGACCTCGATCAAGCGTTCAACCGTGTCATCGAGCAGTCAGCGGTGAAAG
GAAGTGAAGCACAGTGA

Protein sequence :
MNRKELETALVQIGNRMDDRTGAINTPVYFSTAYRHSGIGESTGYDYARTGNPTREVLEKAIATLENGDQGFACSSGMAA
IQTVFSLFQSGDEIIASQDLYGGTYRLFEGGWKKWGLSFSYADPRNLAALEQQITEKTRALFIETPTNPLMQEANIRELA
ALANKHGLLLIVDNTFYTPLLQQPLNEGTHIVIHSASKYLGGHNDVIAGLIVAKGQELCEQIAYYHNGIGGTLSAFDSWL
LIRGMKTLALRMEQHQNNARAIASYLEKHEGVTDVLYPGRGGMLSFRIQSESWVNPFLQSLKLISFAESLGGVESLMTYP
ATQTHADIPEDVRIANGVCNRLLRFSVGIEHVGDLIADLDQAFNRVIEQSAVKGSEAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-72 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-73 43