Gene Information

Name : lysS (BH0098)
Accession : NP_240964.1
Strain : Bacillus halodurans C-125
Genome accession: NC_002570
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 115500 - 117005 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGCGAAGAGCTCGGATTAAATGACCTCTTGGCTGTGCGCCGAGAGAAATTGCAAAATTTAGAAGCCGAAGGGGCAAA
TCCATTTGGTGGGAAGTTTGAGCGTACCGATACTGCCCAGTCTATGAAAGAAAAATATGACGCGAAGTCAAAAGAAGAAT
TAGAAGAAGAAACGCATGAGGTCGTGCTTGCAGGACGAGTGATGACGAAGCGTGGAAAAGGAAAAGCGGGCTTTGCTCAT
ATTCAGGATTTAACAGGGCAAATACAAATTTATGTACGTAAGGATGCAGTAGGCGACAAGTCATACGATTTGTTTACGTC
AATCGATATTGGCGACATCGTGGGCGTCAAAGGTGTTGCTTTTAAGACGAAAGTAGGGGAACTATCGGTTAAAGTACAAG
ACTTTCAACTATTGACGAAGTCATTGCGCCCTCTCCCAGATAAATATCATGGCTTAAAAGATGTGGAGCAGCGCTATCGC
CAACGTTACCTTGACCTCATTGTGAACCCTGAAGTTCGTGATACGTTTGTCTTGCGTAGTAAAATTTTACAATCGATGCG
TCGTTACTTAGATGACCGTGGATATTTAGAGGTGGAAACCCCGACCATGCACTCCATTCCAGGTGGGGCATCGGCTCGTC
CGTTTGTTACTCACCATAATGCACTCGATATGACATTGTATATGCGGATTGCGATTGAGCTACATTTGAAACGGCTTATT
GTTGGTGGGATGGAAAAAGTCTATGAAATTGGTCGAGTGTTTCGTAATGAAGGTGTGTCAACCAGGCATAATCCGGAATT
TACTATGATTGAGCTTTATGAAGCTTATGCGGATTATAACGATATTATGGAATTGACGGAACTACTGATCGCTCATATCG
CCAAAGATGTACTGGGGACGACAACTATTACTTACGGTGAGCATGAAGTGAACTTGGAGCCGAAGTGGCGACGTGTCCAC
ATGGTGGAGGCCATTAAGGAAGAGACAGGTGTAGACTTTTGGAACGAGATGAGTGACGAGGAAGCGCGTGCTTTGGCTAA
GGAGCACAACGTTCCTGTAAAAGAGACGATGACGTATGGGCACGTCGTAAACGAGTTCTTTGAGCACTTTGTGGAAGAAA
AGCTCATTCAACCAACATTCGTTTACGGACACCCTGTTGCGATCTCGCCATTGGCAAAGAAAAATCCTGATGATCCTCGC
TTTACCGATCGATTTGAATTATTTATCGTAGGACGAGAGCATGCAAATGCCTTCTCTGAACTTAATGATCCGATTGATCA
ACGTCACCGTTTTGAACAACAATTAGTTGAGCGGGAGCAAGGGGACGATGAAGCTCATATGATGGATGAGGATTTCGTTG
AATCATTAGAGTATGGGATGCCACCAACTGGTGGGCTAGGAATTGGCATCGATCGATTGGTCATGCTGTTGACAAACTCA
CCGTCCATACGTGATGTGCTATTGTTCCCGCAAATGCGTCATAAAGATTCACCTGCTACTGAATAA

Protein sequence :
MSEELGLNDLLAVRREKLQNLEAEGANPFGGKFERTDTAQSMKEKYDAKSKEELEEETHEVVLAGRVMTKRGKGKAGFAH
IQDLTGQIQIYVRKDAVGDKSYDLFTSIDIGDIVGVKGVAFKTKVGELSVKVQDFQLLTKSLRPLPDKYHGLKDVEQRYR
QRYLDLIVNPEVRDTFVLRSKILQSMRRYLDDRGYLEVETPTMHSIPGGASARPFVTHHNALDMTLYMRIAIELHLKRLI
VGGMEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAYADYNDIMELTELLIAHIAKDVLGTTTITYGEHEVNLEPKWRRVH
MVEAIKEETGVDFWNEMSDEEARALAKEHNVPVKETMTYGHVVNEFFEHFVEEKLIQPTFVYGHPVAISPLAKKNPDDPR
FTDRFELFIVGREHANAFSELNDPIDQRHRFEQQLVEREQGDDEAHMMDEDFVESLEYGMPPTGGLGIGIDRLVMLLTNS
PSIRDVLLFPQMRHKDSPATE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-111 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS NP_240964.1 lysyl-tRNA synthetase VFG1668 Protein 7e-112 51