Gene Information

Name : tktB (BU094)
Accession : NP_239927.1
Strain : Buchnera aphidicola APS
Genome accession: NC_002528
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 96845 - 98842 bp
Length : 1998 bp
Strand : +
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTATTCACGAAAAGAATTAGCTAATGCAATTCGTATGTTAAGTATAGATGCTGTACAAAATGCACAATCAGGACATCC
TGGTATGCCGATGGGAATGGCAGATATTGCTGAAGTGTTATGGAGAAGTTTTTTAAAACATAATCCAGCAAATCCTAATT
GGAATGATCGCGATCGTTTTATATTATCTAACGGACATGGTTCTATGTTGCTCTATAGTTTGTTGCATCTTACAGGCTAT
AATCTACCGATCGAAGAATTAAAAAAATTTAGACAACTGAATTCAAAAACTCCAGGACATCCTGAAACAGGTGAAACACC
TGGTGTAGAAACAACTACTGGTCCATTGGGACAAGGGTTAGCAAATGCTGTTGGTATGGCTATTGCAGAAAGAACTTTAA
GTTCTTATTTTAATCGACCAGGATATGATATAATTAATCATTATACTTGGGTTTTTGTAGGCGACGGTTGCTTAATGGAG
GGTATTTCTCACGAAGTCTGTTCTTTAGCAGGAACTTTAAATCTTGGAAAATTAATCGTTTTTTATGATAAAAATGGTAT
TTCGATAGATGGGAAAACAGCTCACTGGTTCACCGATGATACAGCAAAACGTTTTGAATCTTATAATTGGCATGTATTAG
ATAATATAGATGGTCATGATTCAGAATCTATAGAAAGAAGTATAAAACAAGCAAAATTAATAACAAATCAACCTTCTATT
ATTATTTGCAATACTATTATTGGTTTTGGTTCTCCTAATAAATCAGGAACAGCAGAATCACATGGAGCTCCTCTAGGTGA
GGTTGAAATTTCTTTAATTCGAGAACAATTGAAATGGAATTATCCTCCTTTTCAGATACCTAAAGAAATTTATAAAAAAT
GGAATTTTATAGAAGAAGGATCTAAACTTGAAAAGAAATGGAACGAAAAATTTTCTTTATATCAATCCAAATATCCTGAT
TTATCGACTGAATATTTGCGGCGAATAAATAAAAAATTACCTGTTGAGTGGGATAGAGTAACTAATAATTACATTTCTTT
TTTACAAAAAAATAGACAAAGTATTGCTAGTCGTAAAGCTTCTCAAAATACATTAGAAAAATATGCGATGATTTTACCTG
AGTTAATCGGTGGTTCAGCAGATTTATCACCGAGCAATCTCACTATGTGGTCTAGATGTAATTCCATTAAAGATAATTTA
TCTGGAAACTATATTCATTATGGAGTACGTGAATTTGGAATGACCGCTATTGCAAATGGCATATCTCATCATGGAGGTTT
TATACCTTATACTGCTACATTTTTAATGTTTGTCGAATATGCACGAAATGCAGTTCGTATGGCTGCTTTAATGTGTACCA
AACATATTTTTGTGTATACTCACGATTCTATTGGACTGGGTGAAGATGGTCCTACACATCAACCAGTAGAACAATTATCT
AGTTTGAGAATAACTCCTAATATAGATGTATGGAGACCTAGTGACCAAGTAGAAACAGCTGTTGCTTGGAAAAAAGCTAT
TGAAAAAACATCAGGACCTACAGCATTAATTTTATCACGTCAAAATCTTGATCAATTTGAGAGAAGTTCTGAACAATTAG
AAAACATTTCTTATGGAGCATATATATTATATGATTCAAAAAAAAGACTTGATATTATCTTTATATCAACTGGATCAGAA
TTAAATGTTACTTTAATTGCTGCAAAAAAATTGGCTTCTTTAGGGTATTCTGTACGTGTTGTATCTATGCCCTGTACTAG
TGTTTTTGATAGACAAGATGCTTCTTATAAAGAATTTGTATTACCGACTTATGTTGCTAAAAGGGTTGCTGTTGAAGCTA
GTATAGAAGATTTTTGGTATAAATACGTAGGGATAAATGGTGTAATTATTGGAATGAAAACATTTGGTGAATCTGCTCCA
GCAGAAGATTTATTTAAAAAATTTGGTTTTACTGTACAAAATATCTTCAATAAATCATTAATTTTATTAAAATCTTAA

Protein sequence :
MYSRKELANAIRMLSIDAVQNAQSGHPGMPMGMADIAEVLWRSFLKHNPANPNWNDRDRFILSNGHGSMLLYSLLHLTGY
NLPIEELKKFRQLNSKTPGHPETGETPGVETTTGPLGQGLANAVGMAIAERTLSSYFNRPGYDIINHYTWVFVGDGCLME
GISHEVCSLAGTLNLGKLIVFYDKNGISIDGKTAHWFTDDTAKRFESYNWHVLDNIDGHDSESIERSIKQAKLITNQPSI
IICNTIIGFGSPNKSGTAESHGAPLGEVEISLIREQLKWNYPPFQIPKEIYKKWNFIEEGSKLEKKWNEKFSLYQSKYPD
LSTEYLRRINKKLPVEWDRVTNNYISFLQKNRQSIASRKASQNTLEKYAMILPELIGGSADLSPSNLTMWSRCNSIKDNL
SGNYIHYGVREFGMTAIANGISHHGGFIPYTATFLMFVEYARNAVRMAALMCTKHIFVYTHDSIGLGEDGPTHQPVEQLS
SLRITPNIDVWRPSDQVETAVAWKKAIEKTSGPTALILSRQNLDQFERSSEQLENISYGAYILYDSKKRLDIIFISTGSE
LNVTLIAAKKLASLGYSVRVVSMPCTSVFDRQDASYKEFVLPTYVAKRVAVEASIEDFWYKYVGINGVIIGMKTFGESAP
AEDLFKKFGFTVQNIFNKSLILLKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 66
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 59