Gene Information

Name : hemC (BU591)
Accession : NP_240394.1
Strain : Buchnera aphidicola APS
Genome accession: NC_002528
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 624014 - 624958 bp
Length : 945 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTACAATAAAACATTGAGAATTGCTACCAGAAAAAGTCCTTTAGCTTTGAAACAAACTAAATACGTTCAAAAAAAAAT
ACTATCTTTATATCCAGACTTAAATATCAAATTAGTTCCTATTGTTACTCATGGAGATAATATTTTAAATAAATCTCTTT
CAAAAATTGGAGGAAAAGGCTTATTTATTAAAGAACTAGAACTTGCTTTACTTGAAAATAAAGCAGATATTGCTATTCAT
TCAATGAAAGATCTTCCGGTAAAAATTACAAAAGAATTATGTTTAGTTAGTATATGCAAAAGAGGAAATGCCTTAGATTC
ACTAGTATCTAATAATTATCAATCAATTAATCAGCTGCCCAAAGGTGCTATAGTCGGTACGTCTAGTTTAAGAAGACAAT
GTCAATTAATTACTTATCGACCAGATTTAATTATTTCTCCTTTAAGAGGTAATATAGAAACTAGGATAGCAAAATTAGAT
CAAGGAAAATATGATGCAATTATTTTAGCTACTGAAGGATTAAACAGATTAAGATTAAAAAATAGAATTACTCAGATCAT
ACCTGCCGAATTATCTCTTCCTTCATGTGGACAAGGTGCAATTGGAATTCAATCCAGATTGCATGATAAAAAAGTATTAT
TTTTTTTGTCTCGTCTTAATCATATAAATACTTTTATTGAAATAAATGCAGAAAGAGCTTTTTGTAGAAAACTAGAATCA
GGATGTCAGATTCCCATTGGAAGTTATGCTATTTTGAAAAAAAATAAAATTTGGTTAAGAGGATTGGTGGGATCACCTAA
TGGCAAGATTATATTAAAAGGAGAACGAATAGGTTGTTATAATACAGGAGAAAAAATGGGGTATTCATTAGCAGATGAGC
TGCTTAAAAATGGAGCTAAAAATATTCTTAATAATCTTCATATTAAACAATCTTATTGTATATGA

Protein sequence :
MYNKTLRIATRKSPLALKQTKYVQKKILSLYPDLNIKLVPIVTHGDNILNKSLSKIGGKGLFIKELELALLENKADIAIH
SMKDLPVKITKELCLVSICKRGNALDSLVSNNYQSINQLPKGAIVGTSSLRRQCQLITYRPDLIISPLRGNIETRIAKLD
QGKYDAIILATEGLNRLRLKNRITQIIPAELSLPSCGQGAIGIQSRLHDKKVLFFLSRLNHINTFIEINAERAFCRKLES
GCQIPIGSYAILKKNKIWLRGLVGSPNGKIILKGERIGCYNTGEKMGYSLADELLKNGAKNILNNLHIKQSYCI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-66 51
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-66 51