Name : thyA (BU440) Accession : NP_240252.1 Strain : Buchnera aphidicola APS Genome accession: NC_002528 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 480151 - 480945 bp Length : 795 bp Strand : + Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGAAACAATACATCAAATTAATTAAAAAAATCATCAGGGTTGGAAACCAAAAAAAAGATCGCACAGGAACAGGAACTTT ATCTATTTTTGGTTATAATATGAAATTTGATTTAAAAAAAGGTTTTCCACTTCTTACTACAAAAAAATGTCATATTGCAT CTATCATCTACGAGCTTTTATGGTTTTTAAAAGGAGACACAAACATTTCTTATCTAAATGAAAATAAAATATCAATTTGG AATAATTGGGCAAATGAATCCGGAGATGTTGGTCCAATATACGGAAAACAATGGCGTAATTGGAGTACACCAGAAGGACA CGAAATTGATCAAATAAAAAATGTATTAATACAATTAAAAAAAAATCCCGATTCCCGTAGAATGTTAGTTTCTAGTTGGA ATGTTGGAGATATAGATAAAATGAGATTACCTCCTTGCCATGTTCTATTTCAATTTTATGTATTTAACAATACATTAAGT TGTCAATTGTACCAGCGTTCTTGTGATGTGTTTCTAGGACTACCTTTTAATATAGCTAGTTACTCAATACTTATACACAT GATAGCACAACAATGTGATTTAAAAGTTGGAGATTTTTTGTGGACAGGAGGCGATGTTCACTTATATAATAATCATATAG AATTAGCAAAAAAACAAATACTCAGAATACCTCGAACGCTTCCCAAACTAACCATCCTCAAAAAACCTCAGTCATTATTT CAATATTGTTTCGAAGACTTTAAAATTATTGGATATCATCCTTATCCTGCTATCAAAGGAGAAATATCTATATAA Protein sequence : MKQYIKLIKKIIRVGNQKKDRTGTGTLSIFGYNMKFDLKKGFPLLTTKKCHIASIIYELLWFLKGDTNISYLNENKISIW NNWANESGDVGPIYGKQWRNWSTPEGHEIDQIKNVLIQLKKNPDSRRMLVSSWNVGDIDKMRLPPCHVLFQFYVFNNTLS CQLYQRSCDVFLGLPFNIASYSILIHMIAQQCDLKVGDFLWTGGDVHLYNNHIELAKKQILRIPRTLPKLTILKKPQSLF QYCFEDFKIIGYHPYPAIKGEISI |
Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 7e-77 | 56 |