Gene Information

Name : PA5312 (PA5312)
Accession : NP_253999.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 5982097 - 5983590 bp
Length : 1494 bp
Strand : -
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
ATGACCACCCTGACCCGCGCCGACTGGGAAGCCCGCGCCAAAGACCTGAAGATCGAAGGCCGTGCCTTCGTCAACGGCGA
ATACAGCAACGCCGCCTCCGGCGAGACCTTCGATTGCCTGAGCCCGGTGGATGGCCGCTTCCTGGCCAAGGTCGCCAGTT
GCGACCTGGCCGATGCCGAGCAGGCGGTCAAGGTCGCCCGCAATGCCTTCGATTCCGGCGCCTGGTCGCGCCTGGCGCCG
GCCAAGCGCAAGCAGACGATGATCCGCTTCGCCGATCTGCTGCTGGAGAACGCCGAGGAGCTGGCCCTGCTGGAAACCCT
GGACATGGGCAAGCCGATCAGCGACTCGCTGCACATCGACGTCGCCAGCGCCGCCAACAGCCTGCGCTGGAGCGCCGAGG
CGATCGACAAGATCTATGACGAAGTCGCCGCCACTCCCCATGCCGAGCTGGGCCTGGTGACCCGCGAGCCGGTCGGCGTG
GTCGCCGCCATCGTGCCGTGGAACTTCCCGCTGCTGATGTCCTGCTGGAAACTCGGTCCGGCCCTGGCCACCGGCAACTC
GGTGATCCTCAAGCCCTCCGAGAAGTCGCCGCTGACCGCCATCCGCATCGCCCAGCTGGCCGTCGAGGCCGGCATTCCGA
AAGGCGTGTTCAACGTGCTGCCGGGCTATGGCCACACGGTAGGCAAGGCGCTGGCATTGCACATGGATGTCGACACCCTG
GTGTTCACCGGTTCGACCAAGATCGCCAAGCAACTGATGGTCTATGCCGGCGAGTCGAACATGAAGCGCGTCTGGCTGGA
GGCCGGCGGCAAGAGCCCGAACATCGTCTTCGCCGACGCCCCGGACCTGAAGGCCGCCGCCGAAGCCGCTGCCGGCGCCA
TCGCCTTCAACCAGGGCGAAGTCTGCACCGCCGGTTCGCGCCTGCTGGTGGAGCGCTCCATCAAGGACAAGTTCCTGCCC
CTGGTGATCGAGGCCCTCAAGGGCTGGAAACCGGGCAACCCGCTGGATCCGGAAACCAACGTCGGCGCGCTGGTGGACAC
CCAGCAGATGAACACCGTGCTGTCCTACATCGAGGCCGGTCACAACGACGGCGCCAAGCTGGTCGCCGGCGGCAAGCGGA
CCCTGGAAGAAACTGGTGGCACCTACGTCGAGCCGACTATCTTCGACGGCGTGACCAATGCGATGAAGATCGCCCGCGAG
GAAATCTTCGGCCCGGTGCTCTCGGTGATCGAGTTCGAGGATGCCGAGGAAGCCGTGCGCATCGCCAACGACACGCCCTA
TGGGCTGGCGGCGGCGGTCTGGACCAGCAACCTGTCCAAGGCGCACCTGACTGCCAAGGCCCTGCGCGCCGGCAGCGTCT
GGGTCAACCAGTACGACGGCGGCGACATGACCGCTCCGTTCGGCGGCTTCAAGCAGTCGGGCAACGGTCGCGACAAGTCG
CTGCACGCCTTCGACAAGTACACCGAGCTGAAGGCGACCTGGATCAAGCTCTGA

Protein sequence :
MTTLTRADWEARAKDLKIEGRAFVNGEYSNAASGETFDCLSPVDGRFLAKVASCDLADAEQAVKVARNAFDSGAWSRLAP
AKRKQTMIRFADLLLENAEELALLETLDMGKPISDSLHIDVASAANSLRWSAEAIDKIYDEVAATPHAELGLVTREPVGV
VAAIVPWNFPLLMSCWKLGPALATGNSVILKPSEKSPLTAIRIAQLAVEAGIPKGVFNVLPGYGHTVGKALALHMDVDTL
VFTGSTKIAKQLMVYAGESNMKRVWLEAGGKSPNIVFADAPDLKAAAEAAAGAIAFNQGEVCTAGSRLLVERSIKDKFLP
LVIEALKGWKPGNPLDPETNVGALVDTQQMNTVLSYIEAGHNDGAKLVAGGKRTLEETGGTYVEPTIFDGVTNAMKIARE
EIFGPVLSVIEFEDAEEAVRIANDTPYGLAAAVWTSNLSKAHLTAKALRAGSVWVNQYDGGDMTAPFGGFKQSGNGRDKS
LHAFDKYTELKATWIKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 2e-124 59
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-71 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 5e-72 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 5e-72 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 5e-72 41
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA5312 NP_253999.1 aldehyde dehydrogenase VFG0082 Protein 9e-72 41