Gene Information

Name : ureC (PA4868)
Accession : NP_253555.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : urease subunit alpha
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0804
EC number : 3.5.1.5
Position : 5464821 - 5466521 bp
Length : 1701 bp
Strand : +
Note : Product name confidence: class 2 (High similarity to functionally studied protein)

DNA sequence :
ATGAAAATCAGCAGACAAGCCTACGCCGACATGTTCGGCCCCACCGTCGGCGACCGCGTGCGCCTGGCCGACACCGACCT
GTGGATCGAGGTGGAACGGGACTTCACCGTCTATGGCGAGGAAGTGAAGTTCGGCGGCGGCAAGGTCATCCGCGACGGCA
TGGGCCAGAGCCAGCTGGGCGCGGCGCAGGTGGTCGACACGGTGATCACCAATGCGCTGATCCTCGACCACTGGGGCGTG
GTCAAGGCCGACGTCGGTCTCAAGGACGGGCGCATCCAGGCCATCGGCAAGGCCGGCAACCCGGACATCCAGCCCGGGGT
GAACATCGCCATCGGCGCCGGCACCGAGGTGATCGCCGGCGAGGGCATGATCCTCACCGCCGGCGGCATCGACACGCACA
TCCACTTCATCTGCCCGCAGCAGATCGAAGAGGCGCTGATGAGCGGGGTCACCACCATGATCGGCGGCGGCACCGGCCCC
GCCGCCGGGACCAACGCCACCACCTGCACCTCCGGTCCCTGGCACATGGCGCGGATGCTCCAGGCCGCCGACGCCTTCCC
GATGAACATCGGCTTCACCGGCAAGGGCAACGCCAGCCTGCCGCTGCCGCTGGAGGAGCAGGTGCTCGCCGGCGCCATCG
GCCTGAAGCTGCACGAGGACTGGGGCAGCACCCCGGCGGCGATCGACAACTGCCTGGAGGTCGCCGAGCGCCACGACATC
CAGGTGGCGATCCACACCGACACCCTCAACGAATCCGGCTTCGTCGAGACCACCCTCGGCGCCTTCAAGGGCCGCACCAT
CCACACCTACCACACCGAGGGCGCCGGCGGCGGCCACGCACCGGACATCATCAAGGCCTGCGGCTTCGCCAACGTGCTGC
CCAGCTCGACCAACCCGACACGGCCGTTCACCCGCAATACCATCGACGAGCACCTGGACATGCTGATGGTCTGCCACCAC
CTCGACCCGGCCATCGCCGAGGACGTGGCCTTCGCCGAGTCGCGCATCCGCCGCGAGACCATCGCCGCCGAGGACATCCT
CCACGACCTCGGCGCGTTCAGCATGATCAGCTCCGACAGCCAGGCCATGGGCCGGGTCGGCGAAGTGATCACGCGCACCT
GGCAGACCGCCGACAAGATGAAGCGCCAGCGCGGCCGCCTCGACGGCGACGGCGCGCGCAACGACAACTTCCGCGCCAGG
CGCTACATCGCCAAGTACACCATCAACCCGGCGATCACCCACGGCATCAGCCATGAAGTGGGCTCCGTCGAAGCCGGCAA
GTGGGCCGACCTGGTGCTCTGGCGCCCGGCCTTCTTCGGCGTCAAGCCGAGCCTGATCCTCAAGGGCGGGGCCATCGCCG
CCAGCCTGATGGGCGACATCAACGGCTCGATCCCCACGCCGCAGCCGGTGCACTACCGACCGATGTTCGCCAGCTACGCC
GGCAGCCGTCACGCGACCAGCCTGACCTTCGTCAGCCAGGCCGCCTTCGCCGCCGGCGTACCGCAGCAGCTCGGCCTGCG
CAAGGCCATCGGCGTGGTCAGCGGCTGTCGCGGTGTGCAGAAGACCGACCTGATCCACAACGGCTACCTGCCGACCATCG
AGGTCGACGCACAGAACTACCAGGTACGCGCCGACGGCCAGTTGCTCTGGTGCGAACCGGCGGACGTGCTGCCGATGGCG
CAGCGCTATTTCCTGTTCTGA

Protein sequence :
MKISRQAYADMFGPTVGDRVRLADTDLWIEVERDFTVYGEEVKFGGGKVIRDGMGQSQLGAAQVVDTVITNALILDHWGV
VKADVGLKDGRIQAIGKAGNPDIQPGVNIAIGAGTEVIAGEGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGP
AAGTNATTCTSGPWHMARMLQAADAFPMNIGFTGKGNASLPLPLEEQVLAGAIGLKLHEDWGSTPAAIDNCLEVAERHDI
QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPTRPFTRNTIDEHLDMLMVCHH
LDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDSQAMGRVGEVITRTWQTADKMKRQRGRLDGDGARNDNFRAR
RYIAKYTINPAITHGISHEVGSVEAGKWADLVLWRPAFFGVKPSLILKGGAIAASLMGDINGSIPTPQPVHYRPMFASYA
GSRHATSLTFVSQAAFAAGVPQQLGLRKAIGVVSGCRGVQKTDLIHNGYLPTIEVDAQNYQVRADGQLLWCEPADVLPMA
QRYFLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 0.0 73
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 0.0 73
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 3e-159 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-159 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-159 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-159 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureC NP_253555.1 urease subunit alpha VFG0270 Protein 3e-156 62