Gene Information

Name : pchD (PA4228)
Accession : NP_252918.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : pyochelin biosynthesis protein PchD
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG1021
EC number : -
Position : 4742424 - 4744067 bp
Length : 1644 bp
Strand : +
Note : Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

DNA sequence : 
ATGACTTCCTCGCCCGTCACCCCATCGGCCGTCGACGACGCCCCCGACTGGCCCGCCGCCTTCGTCCGCCGCTATCTCGA
CGCCGGCCACTGGCAGGACCAGAGCTTCGCCGAAGCCCTGGCCACCAGCGCCGCGCGCCATCCGCGGCGGATCGCGCTCT
GCGACGACGACCAGCGGCTCAGCTATGCCGACCTGCTCCAGCGCTGCCGCCGCCTGGCAGCCGGACTGCGCCAGGCCGGC
CTCGCACATGGCGACACGGTAGTGCTGCACCTGCCCAACGGCATCGCCTTCGTCGAGACCTGCTTCGCCCTGTTCCAGCT
CGGCGTACGCCCGGTGCTCGCCCTCCCCGCCCATCGCCAGCATGAGATCAGCGGTTTCTGTCGCTTCGCCGAGGCCAAGG
CCTACATCGGCGCCGAACGGATCGACGGCTTCGACCCACGGCCGATGGCCCGTGAGCTGCTCGCCAGCGGCGCCTGCCGG
ATGGCGCTGATCCACGGCGAAGCCGAGGCGCCGCTGCAAGCGCTGGCACCGCTGTACCAGGCCGACGCGCTGGAAGACTG
CGCCGCCCGCGCCGAGGATATCGCCTGCTTCCAGTTGTCCGGCGGCACCACCGGCACGCCGAAGCTGATTCCCCGGCGTC
ATCGCGAGTATCTCTACAACGTCCGCGCCAGCGCCGAGGTCTGCGGCTTCGACGAGCACACGGTGTACCTCACCGGCTTG
CCGATGGCGCACAACTTCACTCTCTGCTGCCCCGGAGTGATCGGCACGCTGCTGGCCAGCGGCCGCGTGGTGGTCAGCCA
GCGCGCCGATCCCGAGCATTGCTTCGCCCTGATCGCCCGTGAACGGGTCACCCACACCGCCCTGGTACCGCCGCTGGCGA
TGCTCTGGCTGGATGCCCAGGAAAGCCGCCGCGCCGATCTATCCAGCCTGCGTCTGCTCCAGGTCGGCGGCTCCAGGCTC
GGCAGCAGTGCCGCGCAACGCGTCGAACCGGTGCTCGGCTGCCAGTTGCAACAGGTGCTGGGAATGGCCGAGGGGCTGAT
CTGCTACACCCGCCTGGACGATCCGCCCGAACGCGTGCTGCATACCCAGGGCCGGCCGCTGTCGCCGGACGACGAAGTGC
GGGTGGTCGACGCCGAGGGCCGCGAGGTCGGCCCCGGCGAGGTGGGCGAACTGACCGTGCGCGGTCCCTACACCATCCGC
GGCTACTACCGCCTGCCTGAACACAACGCCAAGGCCTTCAGCGCGGACGGCTTCTACCGCACCGGCGACCGGGTCAGCCG
CGACAAGGACGGCTACCTGGTGGTGGAGGGCCGCGACAAGGACCAGATCAACCGCGGCGGCGAGAAGATCGCCGCGGAAG
AGGTGGAGAACCTGCTGATAGCCCATCCGCAGGTGCACGACGCCACCGTCGTGGCGATGCCCGACAGCCTGCTCGGCGAG
CGCACCTGCGCCTTCGTCATCCCGCGCCAGCCGGCGCCCTCGGCGCTGAAGCTGAAGCAATACCTGCACGCCTGCGGGCT
GGCCGCGTTCAAGGTGCCGGACCGCATCGAGCTGGTCCCGGCCTTCCCCCAAACCGGCATCGGCAAGATCAGCAAGAAGG
ACCTGCGCGAGCGCCTGCGCCGCGAGCTGGAGGCCCGCGCATGA

Protein sequence : 
MTSSPVTPSAVDDAPDWPAAFVRRYLDAGHWQDQSFAEALATSAARHPRRIALCDDDQRLSYADLLQRCRRLAAGLRQAG
LAHGDTVVLHLPNGIAFVETCFALFQLGVRPVLALPAHRQHEISGFCRFAEAKAYIGAERIDGFDPRPMARELLASGACR
MALIHGEAEAPLQALAPLYQADALEDCAARAEDIACFQLSGGTTGTPKLIPRRHREYLYNVRASAEVCGFDEHTVYLTGL
PMAHNFTLCCPGVIGTLLASGRVVVSQRADPEHCFALIARERVTHTALVPPLAMLWLDAQESRRADLSSLRLLQVGGSRL
GSSAAQRVEPVLGCQLQQVLGMAEGLICYTRLDDPPERVLHTQGRPLSPDDEVRVVDAEGREVGPGEVGELTVRGPYTIR
GYYRLPEHNAKAFSADGFYRTGDRVSRDKDGYLVVEGRDKDQINRGGEKIAAEEVENLLIAHPQVHDATVVAMPDSLLGE
RTCAFVIPRQPAPSALKLKQYLHACGLAAFKVPDRIELVPAFPQTGIGKISKKDLRERLRRELEARA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 8e-99 51
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-99 51
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-99 51
ybtE CAA21394.1 - Virulence HPI Protein 8e-99 51
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 1e-98 51
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 6e-99 51
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 2e-98 51
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 8e-99 51
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 1e-98 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pchD NP_252918.1 pyochelin biosynthesis protein PchD VFG0168 Protein 0.0 100
pchD NP_252918.1 pyochelin biosynthesis protein PchD VFG1817 Protein 7e-82 46
pchD NP_252918.1 pyochelin biosynthesis protein PchD VFG0932 Protein 3e-100 45