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Name : hpcC (PA4123) Accession : NP_252812.1 Strain : Pseudomonas aeruginosa PAO1 Genome accession: NC_002516 Putative virulence/resistance : Virulence Product : 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 4611013 - 4612473 bp Length : 1461 bp Strand : + Note : Product name confidence: class 2 (High similarity to functionally studied protein) DNA sequence : ATGATCAAACACTGGATCAATGGCCGCGAGGTCGAAAGCAAGGACGTCTTCGAGAACTACAACCCGGCCACCGGCGAGCT GATCGGCGAGGTCGCCAGCGGCGGCGCGGCGGAAATCGACGCGGCGGTGGCGGCGGCCCGGGAAGCCTTCCCGAAATGGG CCAATACCCCGGCCAAGGAGCGCGCGCGCCTGATGCGCCGGCTCGGCGAGCTGATCGACCGGAACGTGCCGCACCTGGCG GAACTTGAGACCCTCGACACCGGCCTGCCGATCCACCAGACGAAGAACGTGCTGATCCCGCGCGCCTCGCACAACTTCGA GTTCTTCGCCGAAGTCTGCACGCGGATGAACGGGCACAGCTATCCGGTCGACGACCAGATGCTCAACTACACCCTGTACC AGCCGGTAGGCGTCTGCGGCCTGGTCTCGCCGTGGAACGTACCGTTCATGACCGCCACCTGGAAGACCGCGCCGTGCCTG GCGCTGGGCAACACGGCGGTGCTGAAGATGTCCGAGCTGTCGCCGCTGACCGCCAACGAGCTGGGCCGCCTGGTGCACGA GGCGGGCATTCCGCCGGGGGTGTTCAACGTGGTCCAGGGCTACGGCGCCAGCGCCGGCGACGCGCTGGTTCGCCACCGCG ACGTGCGCGCGGTGTCCTTCACCGGCGGCACCGCCACCGGGCGACGGATCATGGAGGCGGCCGGGATCAAGAAATACTCG ATGGAACTGGGCGGCAAGTCGCCGGTGCTGGTCTTCGAAGACGCCGACCTCGAGCGGGCGCTGGACGCCGCTCTGTTCAC CATCTTCTCGCTGAACGGCGAGCGCTGCACCGCCGGCAGTCGCATCTTCGTCCAGGAAAGCGTCTACCCGCAGTTCGTCG CCGAGTTCGCCGCGCGCGCCAGGCGCCTGATCGTCGGCGATCCGCAGGACCCGAAGACCCAGGTCGGCTCGATGATCACC CAGGCCCACTACGACAAGGTCACCGGCTACATCCGCATCGGCCTCGAGGAAGGCGCCACCCTGGTGGCCGGCGGCCTGGA GCGTCCGGCCGGCCTGCCGGCGCACCTGAGCAAGGGGCAGTTCATCCAGCCCACGGTGTTCGCCGACGTGGACAACCGCA TGCGCATCGCCCAGGAGGAGATCTTCGGCCCGGTGGTCTGCCTGATCCCGTTCAAGGACGAAGCCGAGGCGCTGCGCCTG GCCAACGACGTGGAATACGGCCTGGCCTCCTACATCTGGACCCAGGACATCGGCAAGGCCCATCGCCTGGCACGCGGCAT CGAGGCCGGGATGGTCTTCATCAACAGCCAGAACGTGCGCGACCTGCGCCAGCCGTTCGGCGGGGTGAAGGCCTCGGGCA CCGGACGCGAAGGCGGGGAATACAGCTTCGAGGTATTCGCCGAGATCAAGAACGTGTGTATATCCATGGGCAGCCATCAC ATCCCCCGCTGGGGCGTGTAG Protein sequence : MIKHWINGREVESKDVFENYNPATGELIGEVASGGAAEIDAAVAAAREAFPKWANTPAKERARLMRRLGELIDRNVPHLA ELETLDTGLPIHQTKNVLIPRASHNFEFFAEVCTRMNGHSYPVDDQMLNYTLYQPVGVCGLVSPWNVPFMTATWKTAPCL ALGNTAVLKMSELSPLTANELGRLVHEAGIPPGVFNVVQGYGASAGDALVRHRDVRAVSFTGGTATGRRIMEAAGIKKYS MELGGKSPVLVFEDADLERALDAALFTIFSLNGERCTAGSRIFVQESVYPQFVAEFAARARRLIVGDPQDPKTQVGSMIT QAHYDKVTGYIRIGLEEGATLVAGGLERPAGLPAHLSKGQFIQPTVFADVDNRMRIAQEEIFGPVVCLIPFKDEAEALRL ANDVEYGLASYIWTQDIGKAHRLARGIEAGMVFINSQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEIKNVCISMGSHH IPRWGV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hpaE | AAO17179.1 | HpaE | Not tested | tcd island | Protein | 0.0 | 79 |
| ORF SG19 | AAN62241.1 | putative aldehyde dehydrogenase | Not tested | PAGI-3(SG) | Protein | 2e-69 | 42 |
| orf17 | AAO17183.1 | Orf17 | Not tested | tcd island | Protein | 3e-63 | 41 |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-65 | 41 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 6e-66 | 41 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 6e-66 | 41 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 6e-66 | 41 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-65 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| hpcC | NP_252812.1 | 5-carboxy-2-hydroxymuconate semialdehyde dehydrogenase | VFG0082 | Protein | 5e-66 | 41 |
