Gene Information

Name : aph (PA4119)
Accession : NP_252808.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Resistance
Product : aminoglycoside 3-N-acetyltransferase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG3231
EC number : -
Position : 4607578 - 4608384 bp
Length : 807 bp
Strand : -
Note : Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

DNA sequence :
ATGCATGATGCAGCCACCTCCATGCCGCCGCAGGCTCCCTCAACCTGGGCCGACTACCTTGCCGGCTACCGCTGGCGAGG
GCAGGGCGAAGGATGTTCCGCGGCCACGGTCCACCGCCTGGAGGCTGCGCGGCGGCCGACCCTGTTCGTCAAGCAGGAAG
TGCTGTCCGCACATGCCGAGCTGCCCGCCGAAATCGCCCGCCTGCGCTGGCTGCACGGTGCCGGCATCGATTGCCCGCAG
GTGCTGAACGAAACCCAGAGCGACGGCCGGCAATGGCTGCTGATGAGCGCAGTGCCGGGGGACACGCTGTCCGCGCTGGC
GCAGCGCGGCGAGCTGGAGCCCGAGCGCCTGGTGCGCCTGGTGGCCGCCGCCCTGCGCCGGCTGCACGATCTCGATCCGG
CTGCCTGTCCCTTCGACCATCGCCTGGAGCGGCGTCTGGACACCGTGCGCCAGCGGGTCGAGGCCGGGCTGGTGGACGAG
GCGGACTTCGACGACGACCATCGCGGTCGCAGCGCCACGGAGCTGTACCGCCTGCTGCTCGACCGGCGTCCGGCGGTCGA
AGACCTGGTGGTCGCCCATGGCGACGCCTGCCTGCCAAATCTGCTGGCGGAGGGGCGGCGCTTCAGCGGCTTCATCGATT
GCGGGCGGCTCGGCGTCGCCGACCGGCACCAGGACCTGGCCCTGGCCGCGCGGGACATCGAGGCCGAACTCGGCGCGGCC
TGGGCCGAGGCCTTCCTCGTCGAATACGGCGGCGATATCGACGGCGAACGGCTGGCGTACTTCAGGCTATTGGACGAGTT
CTTCTAG

Protein sequence :
MHDAATSMPPQAPSTWADYLAGYRWRGQGEGCSAATVHRLEAARRPTLFVKQEVLSAHAELPAEIARLRWLHGAGIDCPQ
VLNETQSDGRQWLLMSAVPGDTLSALAQRGELEPERLVRLVAAALRRLHDLDPAACPFDHRLERRLDTVRQRVEAGLVDE
ADFDDDHRGRSATELYRLLLDRRPAVEDLVVAHGDACLPNLLAEGRRFSGFIDCGRLGVADRHQDLALAARDIEAELGAA
WAEAFLVEYGGDIDGERLAYFRLLDEFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aphA15 CAD91341.1 aminoglycoside phosphotransferase Not tested Not named Protein 3e-34 41
aph15 ACY75516.1 aminoglycocoside phosphotransferase Not tested Tn6060 Protein 3e-34 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aph NP_252808.1 aminoglycoside 3-N-acetyltransferase V00618.gene.p01 Protein 4e-64 53