Gene Information

Name : PA4073 (PA4073)
Accession : NP_252762.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4551143 - 4552630 bp
Length : 1488 bp
Strand : -
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
ATGAGTATTGCCATCGACCCGTCCGTCAGCGCCTTCTTGCGCAGTCCCCATGGCCTGCTGATCGACGGTGAGTCCGGGCC
GGCGCGTTCCGGCGCCGACATGCCGCTGTACGACCCGGCGACCGGTGCCGAGCTGGCGCGCGTGGCCCGCGCCGGCGCCG
AAGACGTCGATCGGGCGGTCGCCGCCGCGCGGCGTGCGTTCGAAGGCAACTGGGCAGGCCAGCGCCCGGCCGATCGCGAG
CGCCTGCTGCTGCGACTGGCGGAACGGATCGAGGCGCATGGCGAGCAACTGGCGCAGTTGGAAACCCTGAACAACGGCAA
GTCGATCAACCTGTCGCGGGCCCTGGAGGTCGGCGCCTCGGTGGAGTTCATCCGCTACATGGCCGGCTGGGCGACCAAGA
TCGAGGGTCGCAGCCTCGACCTGTCGATCGCCGCGGTCCCAGGCGCGCGCTACCGGGCCTACACGGTGCCGGAGCCGGTG
GGCGTGGTCGGAGCCATCGTGCCGTGGAATTTCCCCCTGCTGATGGCGATCTGGAAGATCGTCCCGGCCCTGGCCTGCGG
CTGCACCGTGGTCCTCAAGCCGGCCGACGAAACCCCGCTGACCGCCCTGCGCCTCGGCCAGTTGTGCCTGGAGGCGGGGA
TTCCGCCAGGAGTGGTGAACATCGTCACCGGCACGGGCGCCGAGGCCGGCGCGGCACTGGCGGCGCACCCGGGCATCGAC
AAGCTGGCGTTCACCGGCTCGACCCCGGTGGGCAAGCTGATCGGGCATGCGGCGGTGGAGAACATGACGCGTTTTTCCCT
CGAACTCGGCGGCAAATCCCCGGTGATCATCCTCGATGACACCAGCCTGGACATGGCTGCCGCCGGTTCCGCCGGCGCGA
TCTTCTTCAACCAGGGGCAGGTCTGCACCGCTGGCTCGCGCCTCTATGTGCAGCGCAAGCGTTTCGACCAGGTGCTGGAG
CGCCTGGCGGCCATCGCCGGCGACCTGAGCATCGGCCCCGGCCTGGATCCGACCACGCAGATCAACCCGCTGGTCTCGGC
CAGGCAGCAGGAGCGGGTGCTGGGGATGATCGAAAGCGGGGTGGCCGAGGGCGCCAGCGTGGTCTGCGGTGGGGCGCGCC
AGGGCGAGACGGGGTTCTACGTGCAGCCGACGATCCTTGCCGACGTCACCCCGGGGATGCAGGTGGTGCGCGAGGAAATC
TTCGGGCCGGTGCTGGTGGCGACGCCCTTCGACGATCTCGACGAAGCGGTGCGCCTGGCCAACGACAGCATCTACGGGCT
CGGTGCGAGCATCTGGTCCAACGACCTGCGCCAGGTCATGGACCTGGTACCCAGGATCAAGGCCGGCACGGTATGGGTGA
ACGCCCACAACCTGCTCGACCCGTCGATGCCGTTCGGCGGCTTCAAGCAGTCCGGCATCGGACGCGAGATGGGCCATGCG
GCGATCGAGGCGTACACCGAGAACAAGTCGGTGTGCATCGCCTACTGA

Protein sequence :
MSIAIDPSVSAFLRSPHGLLIDGESGPARSGADMPLYDPATGAELARVARAGAEDVDRAVAAARRAFEGNWAGQRPADRE
RLLLRLAERIEAHGEQLAQLETLNNGKSINLSRALEVGASVEFIRYMAGWATKIEGRSLDLSIAAVPGARYRAYTVPEPV
GVVGAIVPWNFPLLMAIWKIVPALACGCTVVLKPADETPLTALRLGQLCLEAGIPPGVVNIVTGTGAEAGAALAAHPGID
KLAFTGSTPVGKLIGHAAVENMTRFSLELGGKSPVIILDDTSLDMAAAGSAGAIFFNQGQVCTAGSRLYVQRKRFDQVLE
RLAAIAGDLSIGPGLDPTTQINPLVSARQQERVLGMIESGVAEGASVVCGGARQGETGFYVQPTILADVTPGMQVVREEI
FGPVLVATPFDDLDEAVRLANDSIYGLGASIWSNDLRQVMDLVPRIKAGTVWVNAHNLLDPSMPFGGFKQSGIGREMGHA
AIEAYTENKSVCIAY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 3e-71 48
hpaE AAO17179.1 HpaE Not tested tcd island Protein 3e-60 46
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-63 43
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 8e-64 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 8e-64 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 8e-64 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-63 42
unnamed AAK01506.1 putative aldehyde dehydrogenase Not tested PAGI-1 Protein 1e-63 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA4073 NP_252762.1 aldehyde dehydrogenase VFG0082 Protein 4e-64 43