Gene Information

Name : PA4022 (PA4022)
Accession : NP_252711.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 4502271 - 4503791 bp
Length : 1521 bp
Strand : +
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
ATGCGTTACGCCCATCCCGGTAGCGAAGGCGCCATCGTTTCCTTCAAGGCCCGCTACGGCAACTACATCGGCGGCGAGTT
CGTGCCTCCGGTCAAGGGCCAGTACTTCACCAACACCTCGCCGGTGAACGGCCAGCCGATCGCCGAGTTCCCCCGTTCCA
CCGCCGAGGACATCGACAAGGCCCTCGACGCCGCCCACGCCGCCGCCGACGCCTGGGGCCGCACCTCGGTGCAGGAGCGC
TCGAACATCCTGCTGAAGATCGCCGACCGCATCGAGCAGAACCTGGAACTGCTCGCCGTCACCGAGACCTGGGACAACGG
CAAGGCCGTGCGCGAGACCCTCAACGCCGACATCCCCCTGGCCGCCGACCACTTCCGCTACTTCGCTGGCTGCATTCGCG
CCCAGGAAGGCTCCGCCGCCGAGATCAACGACAGCACCGTGGCCTACCACATCCATGAGCCGCTGGGCGTGGTCGGGCAG
ATCATCCCGTGGAACTTCCCGCTGCTGATGGCCGCCTGGAAGCTGGCCCCGGCGCTGGCCGCCGGCAACTGCGTGGTGCT
CAAGCCGGCCGAGCAGACCCCGCTGGGCATCTGCGTGCTGCTGGAACTCATCGGCGACCTGCTGCCGCCGGGCGTGCTCA
ATGTCGTCCAGGGCTTCGGCAGGGAGGCCGGCGAGGCCCTGGCCACCAGCAAGCGCATCGCCAAGATCGCCTTCACCGGT
TCCACCCCGGTCGGCTCGCACATCCTCAAGTGCGCGGCGGAGAACATCATTCCCTCCACCGTCGAGTTGGGCGGCAAGAG
CCCGAACATCTATTTCGAAGACATCATGCAGGCCGAGCCGGCGTTCATCGAGAAGGCCGCCGAGGGCCTGGTGCTGGCCT
TCTTCAACCAGGGCGAGGTGTGCACCTGCCCGTCCCGCGCGCTGGTCCAGGAGTCGATCTACCCGGCGTTCATGGAAGAG
GTGCTGAAAAAGGTCAGGGCGATCAAGCGCGGCGACCCGCTGGACACCGAGACCATGGTCGGCGCCCAGGCTTCCCAGCA
GCAGTACGAGAAGATCCTCTCCTACCTCGACATCGCCCAGCAGGAAGGCGCCGAGCTGCTCGCCGGCGGCAGCGTCGAGA
AGCTCGAAGGCAACCTGGCCAGCGGCTACTACATCCAGCCGACCCTGCTCAAGGGACACAACGGCATGCGCGTGTTCCAG
GAGGAAATCTTCGGCCCGGTGGTCGGCGTCACCACCTTCAAGGACGAAGCCGAGGCCCTGGCCATCGCCAACGACACCGA
GTACGGCCTCGGCGCCGGCCTCTGGACCCGCGACATCAACCGCGCCTACCGCATGGGCCGCGGGATCAAGGCCGGTCGCG
TGTGGACCAACTGCTACCACCTGTACCCGGCCCACGCCGCGTTCGGCGGCTACAAGAAGTCCGGCGTCGGTCGCGAGACG
CACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACGACATCAACCCGCTGGGCTTCTTCTA
G

Protein sequence :
MRYAHPGSEGAIVSFKARYGNYIGGEFVPPVKGQYFTNTSPVNGQPIAEFPRSTAEDIDKALDAAHAAADAWGRTSVQER
SNILLKIADRIEQNLELLAVTETWDNGKAVRETLNADIPLAADHFRYFAGCIRAQEGSAAEINDSTVAYHIHEPLGVVGQ
IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLGICVLLELIGDLLPPGVLNVVQGFGREAGEALATSKRIAKIAFTG
STPVGSHILKCAAENIIPSTVELGGKSPNIYFEDIMQAEPAFIEKAAEGLVLAFFNQGEVCTCPSRALVQESIYPAFMEE
VLKKVRAIKRGDPLDTETMVGAQASQQQYEKILSYLDIAQQEGAELLAGGSVEKLEGNLASGYYIQPTLLKGHNGMRVFQ
EEIFGPVVGVTTFKDEAEALAIANDTEYGLGAGLWTRDINRAYRMGRGIKAGRVWTNCYHLYPAHAAFGGYKKSGVGRET
HKMMLDHYQQTKNLLVSYDINPLGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 3e-149 67
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 7e-157 66
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 7e-157 66
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 7e-157 66
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-156 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA4022 NP_252711.1 aldehyde dehydrogenase VFG0082 Protein 1e-149 67