Gene Information

Name : PA0400 (PA0400)
Accession : NP_249091.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 442008 - 443192 bp
Length : 1185 bp
Strand : +
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
ATGAGCCAGCACGACCAGCATCCCGACGCCCCGGCCCAGGCCTTTGCGACCCGGGTCATCCACGCCGGGCAGGCCCCCGA
TCCCTCGACCGGCGCGATCATGCCGCCGATCTACGCCAACTCCACCTATATCCAGGAAAGCCCCGGGGTACACAAGGGGC
TCGACTACGGCCGCTCCCACAACCCGACCCGCTGGGCCCTGGAGCGCTGCGTGGCCGACCTCGAGGGCGGCACCCAGGCC
TTCGCCTTCGCCTCCGGCCTGGCGGCGATCTCCTCGGTGCTGGAGCTGCTCGACGCCGGTTCCCACATCGTTTCCGGCAA
TGACCTCTACGGCGGTACCTTCCGCCTGTTCGAGCGGGTCCGCCGGCGCAGCGCCGGGCATCGCTTCAGCTTCGTCGACC
CGACCGACCTGCAGGCCTTCGAGGCCGCGCTGACCCCGGAAACCCGCATGGTCTGGGTGGAAACCCCGAGCAACCCGCTG
CTGCGCCTCACCGACCTGCGCGCCATCGCCCAGCTCTGCCGCGCCCGCGGCATCATCAGCGTGGCCGACAACACCTTCGC
CAGCCCCTACATCCAGCGCCCCCTGGAGCTGGGCTTCGACGTGGTGGTGCACTCCACCACCAAGTACCTGAACGGCCATT
CCGACGTGATCGGCGGCATCGCCATCGTCGGCGACAACCCGGACCTGCGCGAGCGCCTGGGCTTCCTGCAGAACTCGGTG
GGCGCCATCTCCGGGCCGTTCGACGCCTTCCTCACCCTGCGCGGGGTGAAGACCCTGGCGCTGCGCATGGAGCGCCATTG
CAGTAACGCCCTGGCCCTGGCCCAGTGGCTGGAGCGCCAGCCGCAAGTGGCGCGGGTCTACTACCCCGGCCTGGCTTCGC
ACCCGCAGCATGAGCTGGCGAAACGGCAGATGCGTGGCTTCGGCGGGATGATCTCCCTCGACCTGCGTTGCGACCTGGCC
GGCGCCCGGCGCTTCCTGGAGAACGTGCGGATCTTCTCCCTGGCGGAGAGCCTGGGCGGGGTGGAAAGCCTGATCGAGCA
TCCGGCGATCATGACCCACGCCAGCATCCCGGCGGAAACCCGCGCCGACCTGGGCATTGGTGACTCGCTGATCCGCCTGT
CGGTGGGCGTCGAGGCGCTGGAGGACCTGCAGGCCGACCTGGCGCAGGCGCTGGCGAAGATCTGA

Protein sequence :
MSQHDQHPDAPAQAFATRVIHAGQAPDPSTGAIMPPIYANSTYIQESPGVHKGLDYGRSHNPTRWALERCVADLEGGTQA
FAFASGLAAISSVLELLDAGSHIVSGNDLYGGTFRLFERVRRRSAGHRFSFVDPTDLQAFEAALTPETRMVWVETPSNPL
LRLTDLRAIAQLCRARGIISVADNTFASPYIQRPLELGFDVVVHSTTKYLNGHSDVIGGIAIVGDNPDLRERLGFLQNSV
GAISGPFDAFLTLRGVKTLALRMERHCSNALALAQWLERQPQVARVYYPGLASHPQHELAKRQMRGFGGMISLDLRCDLA
GARRFLENVRIFSLAESLGGVESLIEHPAIMTHASIPAETRADLGIGDSLIRLSVGVEALEDLQADLAQALAKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-81 47
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-82 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 7e-56 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA0400 NP_249091.1 cystathionine gamma-lyase BAC0207 Protein 3e-73 46