Gene Information

Name : guaA (PA3769)
Accession : NP_252458.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 4225660 - 4227237 bp
Length : 1578 bp
Strand : -
Note : Product name confidence: class 2 (High similarity to functionally studied protein)

DNA sequence :
ATGTCCCAAGACATTCACGCCCACCGTATCCTGATCCTCGATTTCGGCTCCCAGTACACCCAACTGATCGCTCGCCGCGT
GCGCGAGATCGGCGTGTATTGCGAAATCCATCCCTTCGACATGAGCAACGAGGCGATCATCGCCTTCGCGCCGCGCGGCA
TCATCCTCGCCGGTGGCCCCGAGTCGGTACACGAAGCCGACAGCCCGCGCGCGCCGCAGGCGGTGTTCGACCTGAAGGTG
CCGCTGTTCGGCATCTGCTACGGCATGCAGACCATGGCCGAGCAGATGGGCGGCAAGGTGCAGGGCTCCGACCTGCGCGA
GTTCGGCTACGCCCGCGTCGACGTGGTCGGCAAGGCGCGCCTGCTGGACGGCATCGAGGACCACGTGGACGACGACGGCG
TGCTCGGCCTCGACGTGTGGATGAGCCACGGCGACAAGGTCACCGAGATGCCGGCCGGCTTCCACATCCTGGCCAGCACC
CCGAGCTGCCCGATCGCCGCCATGGCCGACGATGCCCGCGCCTACTACGGCGTGCAATTCCACCCGGAAGTCACCCACAC
CAAGCAGGGCCTGCGCATTCTCTCGCGCTTCGTCCTCGACATCTGCGGTTGCGCCGCGCTGTGGACCCCCTCGAACATCG
TCGACGACGCCATCGCCACCGTGCGCGCCCAGGTCGGTTCCTCCAAGGTCCTGCTCGGCCTCTCCGGCGGCGTGGACTCC
TCGGTGGTCGCCGCGCTGCTGCACAAGGCCATCGGCGACCAACTGACCTGCGTGTTCGTCGACAACGGCCTGCTGCGCCT
GCACGAAGGCGACCAGGTGATGGCCATGTTCGCCGAGAACATGGGCGTGAAGGTGATCCGCGCCAACGCCGAGGACAAGT
TCCTCGGCCGCCTGGCCGGCGTCGCCGACCCGGAAGAGAAGCGCAAGATCATCGGCCGCACCTTCATCGAAGTCTTCGAC
GAAGAAGCCACCAAGCTGCAGGACGTGAAGTTCCTCGCCCAGGGCACCATCTACCCCGACGTGATCGAGTCGGCCGGCGC
CAAGACCGGCAAGGCCCACGTGATCAAGTCGCACCACAACGTCGGCGGCCTGCCGGAGGACATGCAGTTCGAACTGGTCG
AGCCGCTGCGCGAACTGTTCAAGGACGAAGTGCGCAAGATCGGCCTGGAGCTGGGCCTGCCCTACGACATGGTCTACCGC
CACCCGTTCCCCGGCCCGGGCCTGGGCGTGCGCATCCTCGGCGAGGTGAAGAAGGAGTACGCCGACCTGCTGCGCCAGGC
CGACCACATCTTCATCGAGGAACTGCGCGCCTTCGACTGGTACCACAAGACCAGCCAGGCGTTCGTGGTGTTCCAGCCAG
TGAAATCGGTCGGCGTGGTCGGCGACGGCCGTCGCTACGCCTGGGTCGTCGCCCTGCGCGCGGTGGAGACCATCGACTTC
ATGACCGCGCGCTGGGCGCACCTGCCCTACGAACTGCTGGAGAAGGTCTCGAACCGCATCATCAACGAGATTGCCGGTAT
CTCCCGGGTCACCTACGACGTGTCGAGCAAGCCGCCGGCGACTATCGAGTGGGAATGA

Protein sequence :
MSQDIHAHRILILDFGSQYTQLIARRVREIGVYCEIHPFDMSNEAIIAFAPRGIILAGGPESVHEADSPRAPQAVFDLKV
PLFGICYGMQTMAEQMGGKVQGSDLREFGYARVDVVGKARLLDGIEDHVDDDGVLGLDVWMSHGDKVTEMPAGFHILAST
PSCPIAAMADDARAYYGVQFHPEVTHTKQGLRILSRFVLDICGCAALWTPSNIVDDAIATVRAQVGSSKVLLGLSGGVDS
SVVAALLHKAIGDQLTCVFVDNGLLRLHEGDQVMAMFAENMGVKVIRANAEDKFLGRLAGVADPEEKRKIIGRTFIEVFD
EEATKLQDVKFLAQGTIYPDVIESAGAKTGKAHVIKSHHNVGGLPEDMQFELVEPLRELFKDEVRKIGLELGLPYDMVYR
HPFPGPGLGVRILGEVKKEYADLLRQADHIFIEELRAFDWYHKTSQAFVVFQPVKSVGVVGDGRRYAWVVALRAVETIDF
MTARWAHLPYELLEKVSNRIINEIAGISRVTYDVSSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 7e-122 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 9e-122 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 8e-122 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-108 49