Gene Information

Name : PA3690 (PA3690)
Accession : NP_252380.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Resistance
Product : metal-transporting P-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 4131536 - 4133758 bp
Length : 2223 bp
Strand : +
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
ATGAGCCACGAACACGCCGACACTTGCTGTCACGGTCACGGTCACGGACATGATCATGGGCACCGCCACGCGCCTCGCCC
GGCGGTGGCCGCCATCGGAACCCTGGCCGGCAACGCCGAGTTGCGCTGGAGCGACCTGCGCATCGAAGCGATGGACTGCC
CGACCGAGGAACGCCTGATCCGCGACGCCCTCGGTCGCCAGCCGGCAGTGGAGTCGCTGGAATTCAACCTGATGCAGCGC
CTGCTGCGCGTCCAGCATCGCTTCGACAGCGTCGAGCCGCTGCAGAAGCTGATCGCCGGCCTCGGCATGCAGGCGGTGCC
GCTGGATGCCGGCGAAAATACCGACGGCCCCTCGCAAGCGCCGGCGAAGCCCTGGTGGCCGCTGGCCCTGGCCGGCGCGA
TGGCGCTGGCCTCGGAGATCGTCGAATGGTTCGGCCTGGCGCCGGACTGGGTGGTCGCCGGCCTCGCCCTGCTGGCCATC
CTCGGCGCCGGCCTGCCGACCTACCGCAAGGGCTGGATCGCACTGAAGAACCGTAACCTGAACATCAACGCCCTGATGAG
TATCGCCGTGACCGGCGCCGTGCTCATCGGCCAGTGGCCGGAAGCGGCGATGGTCAGCGTGCTGTTCGCCATCGCCGAGT
TGATCGAGGCGAAGTCCCTGGATCGCGCGCGCAACGCCATCCGCGGCCTGCTGCAACTGGCTCCGGAACAGGCCACCGTG
CTGGTCGGCGGCGAATGGAAGGAACTGCCGGCCAAGCAAGTGGAACTGGAAGCCACCGTGCGCGTGAAGCCCGGCGAACG
CATCGCACTCGACGGCGAGGTGACCAGCGGCCGCTCCAGCGTCAACCAGGCGCCGATCACCGGCGAAAGCCTGCCGGTGG
AGAAGGAGGTCGGCGAGCCGGTGTTCGCCGGCAGCATCAACGGCGAGGGCGCGCTGGAGTACCGCGTCACCCGCCGCGCC
GACGACAGCACCCTGGCCCGGATCATCCACGCCGTGGAGGAAGCCCAGGGTTCCCGCGCACCGACCCAGCGTTTCGTCGA
CAGTTTCGCCCGCGTCTACACCCCGGTGGTATTCCTCATCGCCCTCGCCACCGCGGTGCTGCCGCCGCTGCTGTTCGGCG
GCGCCTGGCTGGACTGGATCTACCGCGCCCTGGTGCTGCTGGTGATCGCCTGTCCCTGCGCGCTGGTGATCTCCACCCCG
GTGACCATCGTCAGCGGCCTTTCCGCCGCGGCGCGCCTGGGCATCCTGATCAAGGGCGGGGTGTTCCTCGAACTCGGGCG
CAAGCTGTCCTGGGTCGCCCTCGACAAGACCGGCACCATCACCCATGGCAAACCGCAACAGACCGACTACCTGCCGATCG
CGGAGGCTGACGGGACGGATGCGCGCCTGCTCGCCGCCAGCCTGGCCGCGCGTTCCGACCACCCGGTATCGCGCGCCGTG
GCCAACGCAGCGGAAGAGGACGGCCTTGCCCTGGGCGTGGTCGAGGACCTCGCTGCCTTGCCGGGACGAGGCGTCAGCGG
ACGCATCGACGGCGTCCTCTACCACCTCGGCAACCATCGCCTGGTGGAGGAACTGGGCCTCTGCTCGCCGGCCCTGGAAG
AGCGCCTGGACGCCCTGGAGCGCCAGGGCAAGACGGTCATCGCGCTGTGCGATCCGCAGCGCGTGCGGGCCCTCTTCGCC
GTCGCCGACGGGGTCAAGGACAGCAGCCGCGAGGCGATCCACGAGCTGCACGCGCTGGACGTGAAGACCCTGATGCTCAC
CGGCGACAACCCGCACACCGCAGCCGCCATCGCTGCCCAGGTAGGCATCGACGCAGCTCGCGGCAACCTCCTGCCGGAGG
ACAAGCTGCGTGAAGTGGAAGCGCGCCAGGCCGACGGCTCGCGGGTCGGCATGGTCGGCGACGGGATCAACGACGCGCCG
GCCCTGGCCCGCGCCGACATCGGCTTCGCCATGGGCGCGGCGGGCACCGACACGGCCATCGAGACCGCCGGCGTCGCGCT
GATGGACGACGACCTGCGCAAGTTGCCGCAATTCGTCCGGCTGTCGCGCACCACCCACGCGATCCTGGTCCAGAACATCA
CCCTGGCCCTGGGCATCAAGGCGGTGTTCCTCGCCCTTACCCTGGCAGGCGAAGGCACCCTGTGGATGGCGGTATTCGCC
GACATGGGCGCCAGCCTGCTGGTGGTGTTCAACGGTCTGCGACTGTTGCGCAAGCGTTTCTAA

Protein sequence :
MSHEHADTCCHGHGHGHDHGHRHAPRPAVAAIGTLAGNAELRWSDLRIEAMDCPTEERLIRDALGRQPAVESLEFNLMQR
LLRVQHRFDSVEPLQKLIAGLGMQAVPLDAGENTDGPSQAPAKPWWPLALAGAMALASEIVEWFGLAPDWVVAGLALLAI
LGAGLPTYRKGWIALKNRNLNINALMSIAVTGAVLIGQWPEAAMVSVLFAIAELIEAKSLDRARNAIRGLLQLAPEQATV
LVGGEWKELPAKQVELEATVRVKPGERIALDGEVTSGRSSVNQAPITGESLPVEKEVGEPVFAGSINGEGALEYRVTRRA
DDSTLARIIHAVEEAQGSRAPTQRFVDSFARVYTPVVFLIALATAVLPPLLFGGAWLDWIYRALVLLVIACPCALVISTP
VTIVSGLSAAARLGILIKGGVFLELGRKLSWVALDKTGTITHGKPQQTDYLPIAEADGTDARLLAASLAARSDHPVSRAV
ANAAEEDGLALGVVEDLAALPGRGVSGRIDGVLYHLGNHRLVEELGLCSPALEERLDALERQGKTVIALCDPQRVRALFA
VADGVKDSSREAIHELHALDVKTLMLTGDNPHTAAAIAAQVGIDAARGNLLPEDKLREVEARQADGSRVGMVGDGINDAP
ALARADIGFAMGAAGTDTAIETAGVALMDDDLRKLPQFVRLSRTTHAILVQNITLALGIKAVFLALTLAGEGTLWMAVFA
DMGASLLVVFNGLRLLRKRF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF C97 AAN62190.1 putative metal-transporting P-type ATPase Not tested PAGI-2(C) Protein 0.0 67
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-120 48
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 3e-120 48
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 7e-120 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA3690 NP_252380.1 metal-transporting P-type ATPase BAC0298 Protein 0.0 70
PA3690 NP_252380.1 metal-transporting P-type ATPase BAC0461 Protein 1e-84 42
PA3690 NP_252380.1 metal-transporting P-type ATPase BAC0100 Protein 4e-61 42