Gene Information

Name : PA2735 (PA2735)
Accession : NP_251425.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : restriction-modification system protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : -
Position : 3096130 - 3098508 bp
Length : 2379 bp
Strand : -
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
ATGCAGAAACGACAGCAAGACCAAAGCCAGATCAAGTGGGTCGCCGATTTCATCTGGAATATCGCTGACGACCGTCTGCG
CGACGTCTACGTTCGTGGCAAGTACCGCGATGTGATCCTGCCCTTTACCGTGCTACGGCGGATCGATGCAGTGCTGGAAC
CGACCAAACAGGCAGTCTTGGAACGCAAGAAGCTGCTGGACAGCGCCAAAGTGGCGAATCAGAACGGCGCGCTCCAGGCC
GCTGCCGGACAAGCCTTCTACAACGTTTCCGAGTTCACCTTGGCCAAGCTCAAGGCCAGTGCTGCCGGGCAGCGGCTGCG
CGAGGACTTCATCGCTTATCTGGACGGTTTCTCGCCCAACGTGCAGGAAGTTCTCACCAAGTTCAATTTCCGCAACCAGA
TCCAGAAGCTGGTGGATGCCCATATCCTCGGCTACCTGATCGAAGACTTCCTCGATCCCGAGGTCAATCTCTCGCCGCTG
CCGGTCAAGGATGCCGACGGGCGCACCAAGCTGCCCGCGCTCGACAACCATGGCATGGGTACGGTGTTCGAGGAGTTGAT
CCGCCGCTTCAACGAAGAGAACAACGAAGAGGCCGGTGAGCACTTCACCCCGCGCGACGTCGTTCAACTCATGGCCAAGC
TGCTGTTCCTACCAGTGGCCGACCGGATCGAGTCCAGCACCTATTCGCTGTACGACGGCTCTTGTGGCACGGGCGGCATG
CTCACAGTGGCCGAGGAAGCCTTGAAGGAACTGGCTGAGCAGCACGGCAAGGACGTCTCCATCCATCTGTTCGGGCAGGA
AATCAGTGATGAAACCTACGCCATCTGCAAGGCCGACCTACTGCTGAAAGGCGAAGGGGCGGAAGCGGAGAACATCGTCG
GCGGGGCGGATAAATCCACGCTATCCGCCGATCAGTTCCGTTCGCGCGAATTCGACTTCATGATTTCCAATCCGCCCTAC
GGCAAGAGTTGGAAGACCGATCTGGAGCGCATGGGCGGCAAGAAGGAGTTCAGCGACCCGCGCTTTATCGTCAATCACGG
CGGCGATGCCGAGTTCAAGCTCATCACTCGCTCCAGCGACGGGCAGCTCATGTTCCAGGTGAACAAGCTGTCCAAGATGA
AACATGACACCGCGCTCGGCAGCCGCATCGCCCTCGTCCACAACGGCTCGGCGCTATTCACTGGCGACGCTGGCCAAGGC
GAAAGCAATATCCGCCGCTGGGTACTGGAGAACGACTGGCTGGAAGCCATCATCGCCCTGCCGCTCAACATTTTCTACAA
CACTGGGATCGCCACCTATATATGGGTGCTGGCCAACAAAAAAGCTGAGCATCGCAAGGGCAGGGTGCAGTTGATCGACG
CGAGCCAGTGGTTCGCGCCACTGCGCCGCAATCTTGGCAAGAAGAACTGTGAGCTGGCAGAGGGCGACATCCGGCGCATT
CTCGACCTGTATTTGGGCGAAGCGCAGGAAACCGACTCCAGCACCGATCAAAGCAAATGGTTCGACACGCAGGACTTCGG
CTACTGGAAGATCACGGTCGAACGCCCACTGCGCCTGAAGAGCCAGTTGAAAACCAGCGCCATTGATACCCTGCGTTTCG
CCAGTGGCGACGAGGAGTTGCGCACCGAGATCTACGCCGAGCATGGTGACAAGCTCTACACCAGCTTTGCCAAACTGAAG
CCCGAAATCGAAGCTTGGCTCAAGGGTGGCAGCGAGGACGATGATGATGCCGAGGACGGCGACGAAGAAGGCACACACGC
GAAGAAAGCCGTGCCAGAAAAGCGTCGCAAGAGGCTGCTCGATGCCACGACCTGGCAACGCGACAAGGGGCTGCTCGATC
TGGCGCTGCTGGCGCAGAAGGTTTTGGGTGACGCCGTATTCGATGACCACAATGTCTTTCGGGCGGAATTCGATATAGCG
ATGAAGGCACATGACAAAAAGCTCACTGCGGCAGACAAAAAAGCCATCTTCAAGGCGGTGAGCTGGCGTGACGACACCGC
GCCGCCAGTGGTGGCCAAGCGGCACAAGCTGAAAGCCAGCGACGCCTTCATTCCGAGTTTCGATGGCCGCTACTTCATCG
AAACGGGCAAGCACCGCGAAGTCGTCTGGTATGAACCGGATGCCGATCTGCGCGACACCGAGCAAGTGCCGTTGAAGGAA
CTTGGTGGCATCGACGCCTTCTTCGAGCGCGAAGTGCTGCCGCACGCGCCGGATGCGTGGATCGACGGCGAGAAGACCCA
GATCGGCTACGAAATCTCCTTCGCCCGCTACTTCTATAAGCCGACGCCGCTGCGTCCGCTGGACGACATCCGCGCCGATA
TCCTGAAGCTGGAGCAGCAGACGGAAGGTTTGTTGCACAAGATCGTGGGGACAGCTTGA

Protein sequence :
MQKRQQDQSQIKWVADFIWNIADDRLRDVYVRGKYRDVILPFTVLRRIDAVLEPTKQAVLERKKLLDSAKVANQNGALQA
AAGQAFYNVSEFTLAKLKASAAGQRLREDFIAYLDGFSPNVQEVLTKFNFRNQIQKLVDAHILGYLIEDFLDPEVNLSPL
PVKDADGRTKLPALDNHGMGTVFEELIRRFNEENNEEAGEHFTPRDVVQLMAKLLFLPVADRIESSTYSLYDGSCGTGGM
LTVAEEALKELAEQHGKDVSIHLFGQEISDETYAICKADLLLKGEGAEAENIVGGADKSTLSADQFRSREFDFMISNPPY
GKSWKTDLERMGGKKEFSDPRFIVNHGGDAEFKLITRSSDGQLMFQVNKLSKMKHDTALGSRIALVHNGSALFTGDAGQG
ESNIRRWVLENDWLEAIIALPLNIFYNTGIATYIWVLANKKAEHRKGRVQLIDASQWFAPLRRNLGKKNCELAEGDIRRI
LDLYLGEAQETDSSTDQSKWFDTQDFGYWKITVERPLRLKSQLKTSAIDTLRFASGDEELRTEIYAEHGDKLYTSFAKLK
PEIEAWLKGGSEDDDDAEDGDEEGTHAKKAVPEKRRKRLLDATTWQRDKGLLDLALLAQKVLGDAVFDDHNVFRAEFDIA
MKAHDKKLTAADKKAIFKAVSWRDDTAPPVVAKRHKLKASDAFIPSFDGRYFIETGKHREVVWYEPDADLRDTEQVPLKE
LGGIDAFFEREVLPHAPDAWIDGEKTQIGYEISFARYFYKPTPLRPLDDIRADILKLEQQTEGLLHKIVGTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC1769 NP_231404.1 DNA methylase HsdM Not tested VPI-2 Protein 2e-150 45
VC0395_A1367 YP_001217310.1 DNA methylase HsdM Not tested VPI-2 Protein 2e-150 45
VPI2_0017c ACA01834.1 DNA methylase HsdM Not tested VPI-2 Protein 2e-150 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA2735 NP_251425.1 restriction-modification system protein VFG1102 Protein 7e-151 45