Gene Information

Name : PA2366 (PA2366)
Accession : NP_251056.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : uricase
Function : -
COG functional category : S : Function unknown
COG ID : COG3517
EC number : -
Position : 2615461 - 2616945 bp
Length : 1485 bp
Strand : +
Note : class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in (if known).

DNA sequence :
ATGCCCAAGTCATCCGCCGCCGAACAGTCCGGCGAGAGTTCGACCCAGACCCTGTCCCTGCTCGACGAGATCATCGCCAA
GGGCCGCATGGCCCACGACGACAGCCAGCAGGACTATGCCCGCGACATGCTCGCGGAATTCGCCACCCAGGTCCTCGACG
AGGGCATGGCCGTCGACAAGGACACCGTGGCGATGATCAACGACCGCATCAGCCAGATCGATGCGCTGATCAGCGACCAG
CTCAACCAGATCATCCACCACCCCGAGTTGCAGAAGCTGGAAGCCTCCTGGCGCGGCCTGCACCAACTGGTGAGCAACAC
CGAGACCAGCGCGCGGCTCAAGCTGCGCCTGCTGAACGTCGGCAAGAACGAACTGCAGAACGACCTGGAGAAGGCGGTCG
AGTTCGACCAGAGCGCACTGTTCAAGAAGATCTACGAAGAGGAATACGGCACCTTCGGCGGACACCCCTTCAGCCTGCTG
ATCGGCGACTTCACCTTCGGTCGCCATCCGCAGGACATCGGCCTGCTGGAGAAGCTGTCGAACGTCGCCGCGGCTGCCCA
CGCGCCGTTCATCGCCGCCGCCAGCCCACGCCTGTTCGACATGAACAGCTTCACCGAACTGGCCGTGCCACGCGACCTGA
CCAAGATCTTCGAGAGCCTGGAGCTGATCAAGTGGCGCGCCTTCCGCGAGAGCGAGGACTCGCGCTACGTGTCGCTGGTG
CTGCCGAACTTCCTCTTGCGCCTGCCCTACGGCCCGGAGACGCGACCGGTGGAAGGCATGAACTATGTCGAGGACGTCAA
CGGCACCGACCACTCCAAGTACCTCTGGGGCAACGCCGCCTGGGTCCTGGCGCAGCGCATCACCGAGGCCTTCGCCAAGT
ACGGCTGGTGCGCGGCGATCCGCGGCGCGGAAGGCGGCGGCGCGGTCGAGGGCCTACCGGCGCACACGTTCCGCACCAGC
TCCGGCGACCTGTCGCTGAAGTGCCCGACCGAGGTGGCGATCACCGACCGCCGCGAGAAGGAACTCAACGATCTCGGCTT
CATTTCCCTGTGCCACAAGAAGAACAGCGACGTGGCGGTGTTCTTCGGCGGCCAGACCACCAACAAGGCCAGGCTCTACA
ACACCAACGAGGCCAACGCCAACGCGCGCCTGTCGGCGATGCTGCCGTACGTGCTGGCGGCATCGCGCTTCGCCCACTAC
CTGAAGGTGATCATGCGCGACAAGGTCGGCAGCTTCATGACCCGCGACAACGTGCAGACCTACCTGAACAACTGGATCGC
CGACTACGTGCTGATCAACGACAACGCACCGCAGGAAATCAAGGCGCAGTACCCGCTGCGCGAGGCGCGGGTGGATGTCA
GCGAGGTGGCCGGCAAACCGGGAGCCTACCGCGCCACGGTGTTCCTCCGGCCGCACTTCCAGCTCGAGGAACTCAGCGCG
TCGATCCGCCTGGTCGCCAACCTGCCGCCGCCGGTAGCGGCGTGA

Protein sequence :
MPKSSAAEQSGESSTQTLSLLDEIIAKGRMAHDDSQQDYARDMLAEFATQVLDEGMAVDKDTVAMINDRISQIDALISDQ
LNQIIHHPELQKLEASWRGLHQLVSNTETSARLKLRLLNVGKNELQNDLEKAVEFDQSALFKKIYEEEYGTFGGHPFSLL
IGDFTFGRHPQDIGLLEKLSNVAAAAHAPFIAAASPRLFDMNSFTELAVPRDLTKIFESLELIKWRAFRESEDSRYVSLV
LPNFLLRLPYGPETRPVEGMNYVEDVNGTDHSKYLWGNAAWVLAQRITEAFAKYGWCAAIRGAEGGGAVEGLPAHTFRTS
SGDLSLKCPTEVAITDRREKELNDLGFISLCHKKNSDVAVFFGGQTTNKARLYNTNEANANARLSAMLPYVLAASRFAHY
LKVIMRDKVGSFMTRDNVQTYLNNWIADYVLINDNAPQEIKAQYPLREARVDVSEVAGKPGAYRATVFLRPHFQLEELSA
SIRLVANLPPPVAA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec18 YP_851426.1 hypothetical protein Not tested PAI II APEC-O1 Protein 7e-91 41
aec18 AAQ96712.1 Aec18 Not tested AGI-1 Protein 5e-91 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA2366 NP_251056.1 uricase VFG2070 Protein 5e-112 49
PA2366 NP_251056.1 uricase VFG2475 Protein 3e-98 42
PA2366 NP_251056.1 uricase VFG2093 Protein 7e-96 41