Gene Information

Name : PA0219 (PA0219)
Accession : NP_248910.1
Strain : Pseudomonas aeruginosa PAO1
Genome accession: NC_002516
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 247219 - 248709 bp
Length : 1491 bp
Strand : +
Note : Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)

DNA sequence :
GTGTTCGAACTCAGCGATTGGCAACGGCGCGCCGCGACACAGCGCTTCATCGACCAGGCCCTGATCGGCGGCCGCCAGCG
TCCAGCCGCCAGCGGCGCTACCTTCGACGCCATCGATCCGGCGAGCAATCGCCTGCTGGCGCGGGTCGCGGCCTGCGATG
CGGCCGACGTCGACGCGGCAGTGGCCGCCGCCCGCCGCGCCTTCGACGAAGGCCCCTGGGCGCGTCTCGCCCCGGTCGAG
CGCAAGCGCGTGCTGCTGCGCCTGGCCGAGCTGATGCTGGCCCATCGCGAAGAGCTGGCGCTGCTCGACTCGCTGAACAT
GGGCAAGCCGGTGATGGACGCCTGGAACATCGATGTACCCGGCGCCGCCCACGTCTTCGCCTGGTATGCGGAAAGCCTCG
ACAAGCTCTACGACCAGGTCGCGCCGACCGCCCAGCAGACCCTGGCCACCATTACCCGCGTGCCGCTGGGGGTGATCGGC
GCGGTGGTGCCGTGGAACTTCCCGCTCGACATGGCCGCCTGGAAGCTCGCCCCGGCCCTGGCCGCCGGCAACTCGGTGGT
GCTCAAGCCGGCCGAGCAGTCGCCGTTCTCCGCCCTGCGCCTGGCCGAGCTGGCCCTGGAGGCGGGGGTGCCGGAAGGCG
TGCTGAACGTGGTGCCGGGCCTCGGCGAGCAGGCCGGCAAGGCCCTCGGCTTGCACCCGGAGGTGGACGCACTGGTGTTC
ACCGGCTCCACCGAGGTCGGCAAGTACTTCATGCAGTATTCCGCGCAATCCAACCTCAAGCAGGTCTGGCTGGAGTGCGG
CGGCAAGAGTCCGAACCTGGTGTTCGCCGATTGCCGCGATCTTGACCTGGCGGCGGAAAAGGCCGCCTTCGGCATTTTCT
TCAACCAGGGCGAGGTCTGTTCGGCGAACTCGCGCTTGCTGGTGGAGCGTTCGATCCACGACGAGTTCGTCGAGCGCCTG
CTGGCCAAGGCCCGCGACTGGCAGCCGGGCGATCCGCTGGACCCGGCCAGCCGCGCCGGCGCCATCGTCGACCGCCGGCA
GACCGCCGGGATTCTCGCCGCCATCGAGCGGGCGCAAGGCGAGGGCGCGACCCTGCTCGGCGGTGGCCGCCAGTTGACGA
TCAACGGTTCGGACAACTTCATCGAACCGACCCTGTTCGGCGACGTACGCCCGGACATGCAGCTGGCCCGCGAGGAAATC
TTCGGTCCGGTGCTGGCGATCAGCGCCTTCGACTCCGAGGACGAGGCCATACGCCTGGCCAACGACAGCCGCTACGGCCT
CGCCGCCTCGCTGTGGAGCGACGACCTGCACCGTGCACACCGGGTGGCGCGGCGCTTGAATGCCGGAACGGTGTCGGTGA
ATACCGTGGACGCGCTGGACGTCGCGGTGCCTTTCGGCGGCGGCAAGCAGTCCGGCTTCGGTCGCGACCTGTCGCTGCAT
TCCTTCGACAAGTACACCCAGTTGAAGACGACCTGGTTCCAGTTGCGCTGA

Protein sequence :
MFELSDWQRRAATQRFIDQALIGGRQRPAASGATFDAIDPASNRLLARVAACDAADVDAAVAAARRAFDEGPWARLAPVE
RKRVLLRLAELMLAHREELALLDSLNMGKPVMDAWNIDVPGAAHVFAWYAESLDKLYDQVAPTAQQTLATITRVPLGVIG
AVVPWNFPLDMAAWKLAPALAAGNSVVLKPAEQSPFSALRLAELALEAGVPEGVLNVVPGLGEQAGKALGLHPEVDALVF
TGSTEVGKYFMQYSAQSNLKQVWLECGGKSPNLVFADCRDLDLAAEKAAFGIFFNQGEVCSANSRLLVERSIHDEFVERL
LAKARDWQPGDPLDPASRAGAIVDRRQTAGILAAIERAQGEGATLLGGGRQLTINGSDNFIEPTLFGDVRPDMQLAREEI
FGPVLAISAFDSEDEAIRLANDSRYGLAASLWSDDLHRAHRVARRLNAGTVSVNTVDALDVAVPFGGGKQSGFGRDLSLH
SFDKYTQLKTTWFQLR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 8e-108 54
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-57 42
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-57 42
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-57 42
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-57 42
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 4e-57 42
hpaE AAO17179.1 HpaE Not tested tcd island Protein 5e-57 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
PA0219 NP_248910.1 aldehyde dehydrogenase VFG0082 Protein 2e-57 42