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Name : exaC (PA1984) Accession : NP_250674.1 Strain : Pseudomonas aeruginosa PAO1 Genome accession: NC_002516 Putative virulence/resistance : Virulence Product : NAD+ dependent aldehyde dehydrogenase ExaC Function : - COG functional category : C : Energy production and conversion COG ID : COG1012 EC number : - Position : 2169988 - 2171508 bp Length : 1521 bp Strand : + Note : Product name confidence: class 1: Function experimentally demonstrated in P. aeruginosa DNA sequence : ATGATCTACGCAGCGCCCGGAACCCCCGGTGCCGTCGTCACCTTCAAGCCTCGCTACGGCAACTACATCGGCGGCGAGTT CGTGCCTCCGGTCAAGGGCCAGTACTTCACCAACACCTCGCCGGTGAACGGCCAGCCGATCGCCGAGTTCCCCCGTTCCA CCGCCGAGGACATCGACAAGGCCCTCGACGCCGCCCACGCCGCCGCCGAGGCCTGGGGCCGCACCTCGGTGCAGGAGCGT TCGAACATCCTGCTGAAGATCGCCGACCGCATCGAGCAGAACCTGGAACTGCTCGCCGTCACCGAGACCTGGGACAACGG CAAGGCCGTGCGCGAGACCCTCAACGCCGACATTCCCCTGGCCGCCGACCACTTCCGCTACTTCGCCGGCTGCATCCGCG CCCAGGAAGGCTCCGCCGCCGAGATCAACGACAGCACCGTGGCCTACCACATCCATGAGCCGCTGGGCGTGGTCGGGCAG ATCATCCCGTGGAACTTCCCGCTGCTGATGGCCGCCTGGAAGCTGGCCCCGGCGCTGGCCGCCGGCAACTGCGTGGTGCT CAAGCCGGCCGAGCAGACCCCGCTGGGCATCTGCGTGCTGCTGGAACTCATCGGCGACCTGCTGCCGCCGGGCGTGCTCA ACGTCGTCCAGGGCTTCGGCAGGGAGGCCGGCGAGGCCCTGGCCACCAGCAAGCGCATCGCCAAGATCGCCTTCACCGGT TCCACCCCGGTCGGCTCGCACATCCTCAAGTGCGCGGCGGAGAACATCATTCCCTCCACCGTCGAGCTGGGCGGCAAGAG CCCGAACATCTATTTCGAAGACATCATGCAGGCCGAGCCGGCGTTCATCGAGAAGGCCGCCGAGGGCCTGGTGCTGGCTT TCTTCAACCAGGGCGAGGTGTGCACCTGCCCGTCCCGCGCGCTGGTCCAGGAGTCGATCTACCCGGCGTTCATGGAAGAG GTGCTGAAAAAGGTCAGGGCGATCAAGCGCGGCGACCCGCTGGACACCGAGACCATGGTCGGCGCCCAGGCTTCCCAGCA GCAGTACGAGAAGATCCTCTCCTACCTCGACATCGCCCAGCAGGAAGGCGCCGAGCTGCTCGCCGGCGGCAGCGTCGAGA AGCTCGAAGGCAACCTGGCCAGCGGCTACTACATCCAGCCGACCCTGCTCAAGGGGCACAACGGCATGCGCGTGTTCCAG GAGGAAATCTTCGGCCCGGTGGTCGGCGTCACCACCTTCAAGGACGAAGCCGAGGCCCTGGCCATCGCCAACGACACCGA GTACGGCCTCGGCGCCGGCCTCTGGACCCGCGACATCAACCGCGCCTACCGCATGGGCCGCGGGATCAAGGCCGGTCGCG TGTGGACCAACTGCTACCACCTGTACCCGGCCCACGCCGCGTTCGGCGGCTACAAGAAGTCCGGCGTCGGTCGCGAGACG CACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACCTGCTGGTGAGCTACGACATCAACCCGCTGGGCTTCTTCTG A Protein sequence : MIYAAPGTPGAVVTFKPRYGNYIGGEFVPPVKGQYFTNTSPVNGQPIAEFPRSTAEDIDKALDAAHAAAEAWGRTSVQER SNILLKIADRIEQNLELLAVTETWDNGKAVRETLNADIPLAADHFRYFAGCIRAQEGSAAEINDSTVAYHIHEPLGVVGQ IIPWNFPLLMAAWKLAPALAAGNCVVLKPAEQTPLGICVLLELIGDLLPPGVLNVVQGFGREAGEALATSKRIAKIAFTG STPVGSHILKCAAENIIPSTVELGGKSPNIYFEDIMQAEPAFIEKAAEGLVLAFFNQGEVCTCPSRALVQESIYPAFMEE VLKKVRAIKRGDPLDTETMVGAQASQQQYEKILSYLDIAQQEGAELLAGGSVEKLEGNLASGYYIQPTLLKGHNGMRVFQ EEIFGPVVGVTTFKDEAEALAIANDTEYGLGAGLWTRDINRAYRMGRGIKAGRVWTNCYHLYPAHAAFGGYKKSGVGRET HKMMLDHYQQTKNLLVSYDINPLGFF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| VC0819 | NP_230467.2 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 1e-150 | 67 |
| aldA | AAC12273.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-158 | 66 |
| aldA | AAK20747.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-158 | 66 |
| aldA | AAK20776.1 | aldehyde dehydrogenase | Virulence | VPI | Protein | 2e-158 | 66 |
| aldA-1 | YP_001216300.1 | aldehyde dehydrogenase | Not tested | VPI-1 | Protein | 2e-157 | 66 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| exaC | NP_250674.1 | NAD+ dependent aldehyde dehydrogenase ExaC | VFG0082 | Protein | 6e-151 | 67 |
