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Name : ldcA (PA1818) Accession : NP_250509.1 Strain : Pseudomonas aeruginosa PAO1 Genome accession: NC_002516 Putative virulence/resistance : Virulence Product : lysine-specific pyridoxal 5'-phosphate-dependent carboxylase, LdcA Function : - COG functional category : E : Amino acid transport and metabolism COG ID : COG1982 EC number : - Position : 1974821 - 1977076 bp Length : 2256 bp Strand : + Note : class 2: Function of highly similar gene experimentally demonstrated in another organism (and gene context consistent in terms of pathways its involved in (if known). DNA sequence : ATGTATAAAGACCTCAAATTTCCCGTCCTCATCGTCCATCGCGACATCAAGGCCGACACCGTTGCCGGCGAACGCGTGCG GGGCATCGCCCACGAACTGGAGCAGGACGGCTTCAGCATTCTCTCCACCGCCAGCTCCGCCGAGGGGCGCATCGTCGCTT CCACCCACCACGGCCTGGCCTGCATTCTGGTCGCCGCCGAAGGTGCCGGGGAAAACCAGCGCCTGCTGCAGGATGTGGTC GAACTGATCCGCGTGGCCCGCGTGCGGGCGCCGCAATTGCCGATCTTCGCCCTCGGCGAGCAGGTGACCATCGAGAACGC GCCGGCCGAGTCCATGGCCGACCTGCACCAGTTGCGCGGCATCCTCTACCTGTTCGAAGACACCGTGCCGTTCCTCGCCC GCCAGGTCGCCCGGGCGGCGCGCAACTACCTGGCCGGGCTGCTGCCGCCATTCTTCCGTGCGCTGGTCGAGCACACCGCG CAGTCCAACTATTCCTGGCATACGCCGGGCCACGGCGGCGGTGTCGCCTATCGCAAGAGTCCGGTGGGACAGGCGTTCCA CCAGTTCTTCGGGGAGAACACGCTGCGTTCCGACCTGTCGGTCTCGGTCCCCGAGCTGGGATCGCTGCTCGACCATACCG GCCCCCTGGCCGAGGCCGAGGACCGTGCCGCGCGCAATTTCGGCGCCGACCATACCTTCTTCGTGATCAATGGCACTTCC ACCGCGAACAAGATCGTCTGGCACTCCATGGTCGGTCGCGAAGACCTGGTGCTGGTGGACCGCAACTGCCACAAGTCGAT CCTCCACTCGATCATCATGACCGGGGCGATACCGCTCTACCTGACTCCGGAACGCAACGAACTGGGGATCATCGGGCCGA TCCCGCTGAGCGAATTCAGCAAGCAGTCGATCGCCGCGAAGATCGCCGCCAGCCCGCTGGCGCGCGGCCGCGAGCCGAAG GTGAAGCTGGCGGTGGTGACTAACTCCACCTACGACGGCCTGTGCTACAACGCCGAGCTGATCAAGCAGACCCTCGGCGA CAGCGTCGAGGTGTTGCACTTCGACGAGGCTTGGTACGCCTATGCCGCGTTCCACGAGTTCTACGACGGACGCTATGGCA TGGGCACCTCGCGCAGCGAGGAGGGACCCCTGGTGTTCGCCACCCACTCCACGCACAAGATGCTCGCCGCCTTCAGCCAG GCCTCGATGATCCACGTGCAGGATGGCGGGACCCGGAAGCTGGACGTGGCGCGCTTCAACGAAGCCTTCATGATGCACAT CTCGACCTCGCCGCAGTACGGCATCATCGCTTCGCTGGACGTGGCTTCGGCGATGATGGAAGGGCCCGCCGGGCGTTCGC TGATCCAGGAGACCTTCGACGAGGCCCTCAGCTTCCGCCGGGCCCTGGCCAACGTACGGCAGAACCTGGACCGGAACGAC TGGTGGTTCGGCGTCTGGCAGCCGGAGCAGGTGGAGGGCACCGACCAGGTCGGCACCCATGACTGGGTGCTGGAGCCGAG CGCCGACTGGCACGGCTTCGGCGATATCGCCGAAGACTACGTGCTGCTCGACCCGATCAAGGTCACCCTGACCACCCCGG GCCTGAGCGCTGGCGGCAAGCTCAGCGAGCAGGGGATTCCGGCCGCCATCGTCAGCCGCTTCCTCTGGGAGCGCGGGCTG GTGGTGGAGAAAACCGGTCTCTACTCCTTCCTGGTGCTGTTCTCGATGGGCATCACCAAGGGCAAGTGGAGCACCCTGGT CACCGAACTGCTCGAATTCAAGCGCTGTTACGACGCCAACCTGCCGCTGCTTGACGTCTTGCCCTCCGTGGCCCAGGCCG GCGGCAAGCGCTACAACGGAGTGGGCCTGCGCGACCTCAGCGACGCCATGCACGCCAGCTACCGCGACAACGCCACGGCG AAGGCCATGAAGCGCATGTACACGGTGCTGCCGGAGGTCGCGATGCGGCCGTCCGAGGCCTACGACAAGCTGGTGCGCGG CGAGGTCGAGGCGGTACCGATCGCTCGGTTGGAAGGGCGCATCGCGGCCGTCATGCTGGTACCCTATCCGCCGGGTATCC CGCTGATCATGCCGGGTGAGCGCTTCACCGAGGCGACCCGCTCGATCCTCGACTATCTCGAGTTCGCGCGGACCTTCGAG CGCGCCTTCCCTGGTTTCGACTCCGATGTGCATGGCCTGCAGCATCAGGACGGACCGTCCGGGCGCTGCTATACCGTTGA ATGCATAAAGGAATGA Protein sequence : MYKDLKFPVLIVHRDIKADTVAGERVRGIAHELEQDGFSILSTASSAEGRIVASTHHGLACILVAAEGAGENQRLLQDVV ELIRVARVRAPQLPIFALGEQVTIENAPAESMADLHQLRGILYLFEDTVPFLARQVARAARNYLAGLLPPFFRALVEHTA QSNYSWHTPGHGGGVAYRKSPVGQAFHQFFGENTLRSDLSVSVPELGSLLDHTGPLAEAEDRAARNFGADHTFFVINGTS TANKIVWHSMVGREDLVLVDRNCHKSILHSIIMTGAIPLYLTPERNELGIIGPIPLSEFSKQSIAAKIAASPLARGREPK VKLAVVTNSTYDGLCYNAELIKQTLGDSVEVLHFDEAWYAYAAFHEFYDGRYGMGTSRSEEGPLVFATHSTHKMLAAFSQ ASMIHVQDGGTRKLDVARFNEAFMMHISTSPQYGIIASLDVASAMMEGPAGRSLIQETFDEALSFRRALANVRQNLDRND WWFGVWQPEQVEGTDQVGTHDWVLEPSADWHGFGDIAEDYVLLDPIKVTLTTPGLSAGGKLSEQGIPAAIVSRFLWERGL VVEKTGLYSFLVLFSMGITKGKWSTLVTELLEFKRCYDANLPLLDVLPSVAQAGGKRYNGVGLRDLSDAMHASYRDNATA KAMKRMYTVLPEVAMRPSEAYDKLVRGEVEAVPIARLEGRIAAVMLVPYPPGIPLIMPGERFTEATRSILDYLEFARTFE RAFPGFDSDVHGLQHQDGPSGRCYTVECIKE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66195.1 | putative cadaverin decarboxylase | Virulence | PAI III 536 | Protein | 2e-130 | 45 |
| cadA | NP_756988.1 | lysine decarboxylase, inducible | Not tested | PAI II CFT073 | Protein | 2e-127 | 45 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ldcA | NP_250509.1 | lysine-specific pyridoxal 5'-phosphate-dependent carboxylase, LdcA | VFG1670 | Protein | 1e-130 | 45 |
