Gene Information

Name : smpB (VC0848)
Accession : NP_230495.1
Strain :
Genome accession: NC_002505
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 914726 - 915211 bp
Length : 486 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACAAAAAAGAAAACCAATACCAAAGCGGGTAGCAACACTATCGCGCTGAACAAAAAAGCTCGCCACGAATACTTCAT
CGAAGATGAATTTGAAGCCGGCATGGAGCTACAAGGCTGGGAAGTCAAATCACTTCGCCAAGGTAAAGCCAACATTGCAG
AAAGCTACGTCTACATCAAAGATGGCGAAGCGTTCATTTCCGGTATGACCATCATTCCGTTGCAGCAAGCCTCCACTCAC
GTGGTAGCCAACCCTACCCGTATCCGCAAGCTGCTACTTTCACGCCGCGAGCTGGACAACCTGTTTGGCCGCATCAACCG
TGAAGGGATGACACTAACCGCATTGTCACTCTACTGGTCTCGTTCGTGGGTCAAAATCAAAATTGGCGTTGCGAAAGGTA
AGAAACTGCACGACAAACGTGAAGATCTGAAAGAAAAAGAGTGGCAACGCCAAAAAGATCGAGTGATGAAGAGCGCGTTG
CGCTAA

Protein sequence :
MTKKKTNTKAGSNTIALNKKARHEYFIEDEFEAGMELQGWEVKSLRQGKANIAESYVYIKDGEAFISGMTIIPLQQASTH
VVANPTRIRKLLLSRRELDNLFGRINREGMTLTALSLYWSRSWVKIKIGVAKGKKLHDKREDLKEKEWQRQKDRVMKSAL
R

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-64 100
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-18 44