Gene Information

Name : tpx (VC0824)
Accession : NP_230472.1
Strain :
Genome accession: NC_002505
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 885773 - 886267 bp
Length : 495 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence : 
ATGACTGTTACATTTCAAAATAATCCTGTTTCTATTTCTGGCTCTTTTCCTAAAGTAGGTGATCGTTTGCCTAGTTTTAC
TCTTTGTGGTGCTGATTTGAACGATCTTAGCAATGAAGATTTTAAAGGAAAAAAGATTGTAATGAGCATTTTCCCCAGTA
TCGACACTCCGGTTTGTTCTAAAAGTGTGAAAGTTCTTCAAAATGCACTTATGACTCGCAATGACACAGTGCTTCTCTGT
GTTTCAGCAGATCTGCCTTTTGCTATGTCTCGCTTTTGTACAGAGCATGCAGTAGCTAATGTCACGAATGCGTCGTTTTT
TCGTGAGCCTGCTTTTACTGAACGCTTCGGTGTAAATCTAAATGAAGGTGCTTTACGTGGGCTTGCTGCTAGAGCAGTGA
TTGTTGCAGATGAGTTCGGTGTAATTACCCACAGTGAATTAGTCAATGAAATCACCAATGAACCAGATTACGATCGTATT
TTGATGTCACTATAA

Protein sequence : 
MTVTFQNNPVSISGSFPKVGDRLPSFTLCGADLNDLSNEDFKGKKIVMSIFPSIDTPVCSKSVKVLQNALMTRNDTVLLC
VSADLPFAMSRFCTEHAVANVTNASFFREPAFTERFGVNLNEGALRGLAARAVIVADEFGVITHSELVNEITNEPDYDRI
LMSL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 8e-72 100
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 6e-72 100
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 2e-71 99
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 1e-71 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx NP_230472.1 thiol peroxidase VFG0087 Protein 2e-72 100