Gene Information

Name : murD (VC2403)
Accession : NP_232033.2
Strain :
Genome accession: NC_002505
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 2572228 - 2573562 bp
Length : 1335 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGTCAATTTCAATGGACCGTTGGCAAGGCATACAACATGTGGTCGTCGTAGGGCTCGGGATTACCGGGCTCTCTGTCGT
TAATTATCTGAGAAAATATCATCCGTCGGTAACCGTGCAGGTTATCGATACGCGCGAAGCACCACCGGGGCAAGAGCAGC
TTTCGTCGGACGTTGCACTGCATCGTAGCGGTTGGAATCTTGAGTGGTTACTCAATGCCGATTTGGTAGTCACCAACCCA
GGCATTGCGTTGGCGACGCCGGAAATCCAACAAGTGCTGGCCGCTGGAATTCCTGTTGTCGGTGATATTGAGCTCTTTGC
ATGGCATGTGGATACACCCGTTATTGCGATCACTGGCTCAAATGGCAAAAGCACCGTCACTGATTTAAGCGGTGTGTTAG
CCAATGCTGCTGGTGTGAAGGCCGCGGTAGGTGGCAATATTGGGGTTCCGGCACTGGATCTGATTTCTCCAGACGTTGAA
CTGTATGTGCTTGAGCTATCAAGCTTCCAATTAGAAACTACCTCTAGCTTAAAACTGAAAGCGGCCGCGTTTCTCAATCT
TTCTGAAGATCATATGGATCGTTATCAGGGGATGGAAGATTACCGCCAAGCCAAACTGCGCATTTTCGATCATGCCGAAA
CCGCAGTGGTGAATGCCGATGATACTCAAACTTTTCCTGACCACGCGGCACATCTGCAAGTGGTGACGTTTGGTGTCGAG
CAAGCTGCACAATTTAGCCTTGCTCAACATCAAGGCCGCGAATACCTTTTTGCGCGCGATGAGGCCGTCATGGCGTGTGC
TGAGCTGAGTTTAGTTGGCCGTCATAACGTGGCAAACGTACTTACCGTGTTAGCTTTGCTGGATTCAGCCGGAGTAAACT
TCCGTTTGGCTTTGGATGCACTCAAGTCTTACACAGGTTTGACACACCGCTGCCAAGTGGTTGCCGATAATCACGGCATC
AAGTGGGTCAATGATTCTAAAGCGACCAATGTTGCGAGTACGCTGGCAGCATTGTCGGGATTAAAAATCGAAGGTCAGCT
CTATTTGTTGGTTGGTGGCGTAGGTAAAGGGGCGGATTTCACGCCGCTCGCCCCCGTATTGGCGACATTGCCTGTGCAAT
TGTGCTGCTTTGGTGTGGACGGCCATCAATTTATGCCACTGCACCCTTCGGCTCGGTTTTATGACTCGATGGAGAGCATA
ATTCGCTCAATCCGCCCGCAATTAAAAAGTGGGGATATGGTGCTGCTCTCTCCCGCTTGTGCGAGCTTTGATCAGTTCAA
AAACTTTATGGCGCGTGGGGATATTTTTGCCCAACTCGCTCGGCAATATGCATAA

Protein sequence :
MSISMDRWQGIQHVVVVGLGITGLSVVNYLRKYHPSVTVQVIDTREAPPGQEQLSSDVALHRSGWNLEWLLNADLVVTNP
GIALATPEIQQVLAAGIPVVGDIELFAWHVDTPVIAITGSNGKSTVTDLSGVLANAAGVKAAVGGNIGVPALDLISPDVE
LYVLELSSFQLETTSSLKLKAAAFLNLSEDHMDRYQGMEDYRQAKLRIFDHAETAVVNADDTQTFPDHAAHLQVVTFGVE
QAAQFSLAQHQGREYLFARDEAVMACAELSLVGRHNVANVLTVLALLDSAGVNFRLALDALKSYTGLTHRCQVVADNHGI
KWVNDSKATNVASTLAALSGLKIEGQLYLLVGGVGKGADFTPLAPVLATLPVQLCCFGVDGHQFMPLHPSARFYDSMESI
IRSIRPQLKSGDMVLLSPACASFDQFKNFMARGDIFAQLARQYA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 7e-55 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 7e-55 42