Gene Information

Name : VC1757 (VC1757)
Accession : NP_231393.1
Strain :
Genome accession: NC_002505
Putative virulence/resistance : Resistance
Product : AcrB/AcrD/AcrF family transporter
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 1892430 - 1895480 bp
Length : 3051 bp
Strand : +
Note : similar to GB:AL009126; identified by sequence similarity

DNA sequence :
ATGGATATTGCACGTTATACCCTTGCCAAACGCACCAGCGTTTGGGTGCTGATAGCCCTAACCTTGATTGGCGGCTACAT
CAGCTACCTCAAATTGGGTCGTTTTGAAGACCCTGAGTTTGTGATTCGCCAAGCGGTGATTGTGACGCCTTATCCGGGTG
CCACCGCGCAAGAAGTTTCCGATGAAGTGACCGATGTCATCGAAGGCGCAGTGCAAGCTCTGCAAGAGCTAAAAGAAGTC
AAATCGGTTTCGATGCAAGGCCGCTCTGAAGTGACGGTAGAAATCAAACTCGAATTTGCCAAATCCTCCGCGCAGTTGCA
GCAGGTATGGGACAAATTACGCCGTAAAGTCGCGGATGCGCAGCGCCAACTGCCTCCCGGTGCCGGCGCTTCAATCGTTA
ACGATGACTTCTCTGACGTGTACGCGCTGTTTTATGCGGTAACTGGGGAAGGCTTTAGCGACAAACAGCTCCAAGACTAC
GTCGATACGCTACGCCGTGAACTGGTTCTGGTGCCGGGTGTGGCCAAAGCCGCTACGCTGGCCGAGCAGCAAGAAGCAAT
CTTTATCGAGATGTCCAGCGAACGCATGGCGGAATTTGGCCTTTCGGTTGAACGCGTATTGCAAGTGCTACAAAAGCAGA
GCCTAGTCACCGTTGCAGGCAGCGTCGATGCTCAGCAGATGCGCATTCCGGTGATCCCTAAATCCAACATCAGCTCCTTG
GCTGACCTGACTAATTTGCAAGTGGCGGTCGGTAGCAACAATGCGGTGGTACGCCTAGGTGATATTGCCAACATCAGCCG
TGGCTACACCGAGCCAGCATCGATGCTGATGCGCTATAACGGTCAGCGTGCAATTGGCTTTGGTATCTCGAATGTCACCG
GCGGTAACGTGGTCGAGATGGGCGATGCCGTCAAAGCACGCTTGGCTGAACTTGAAAGCCAGCGTCCACTGGGCATGGAT
CTGCATGTGATTTCGATGCAGTCTGACTCGGTGCGCGCTTCGGTGGCCAATTTTATCGATAACCTGATTGCCGCTGTCGC
CATCGTGTTTGTCGTGCTCTTGCTGTTTATGGGCGTACGCTCAGGTGTCATCATCGGTTTTGTTCTATTGCTTACCGTTG
CCGGTACCTTATGTGTGATGCTGATTGATGACATCGCCATGCAGCGGATTTCGCTCGGCGCGCTCATCATCGCCCTCGGC
ATGTTGGTGGATAACGCGATTGTGGTTACCGATGGCGTACTCGTGCGGTTTCAGCAAGAGCCGAACGCCGATAAACAGCA
AGTGGTCTCTGAGGTGGTCAATGCCACAAAATGGCCACTGCTGGGCGGTACGGTGGTGGGCATTTTTGCCTTCAGCGCAA
TTGGCCTCTCCCCTTCCGATATGGGCGAATATGCTGGCTCACTGTTTTGGGTGATCCTCTACTCGATGTTTTTGAGTTGG
GTGTTTGCGGTGACCGTCACCCCCATGCTGTGCCATGACTTTCTACGCGTTAAAGCTCCCACCAAAGAGGCGAAACCGTC
TAAATTGGTGACGGGTTATAAAGCCGTACTGCAATGGGTGTTAAGCCACCGCGTGGTCAGCTGTGCGATGCTGCTCGGCA
CCTTAGTAGCTGCGGTGTGGGGCGCTCAGTTTATTCCGCCGGGCTTTATGCCAGAGTCGCAACGACCACAATTTGTGGTG
GATGTGTACTTGCCACAAGGCTCGGATATTCGCCGCACCGAACAGGTTGTCGCCAGCATTGAGAAAGACGTGACGCAAAA
AGACGGTATTACCAATATCACCAGTTTCATCGGCGGTGGTGGCCTGCGTTTTATGCTGACCTACTCACCCGAGGCGCGTA
ACCCAAGTTACGGCCAACTGCTGATTGATATTGATGACTACACCAAAATTGCCCCATTAGTAGGCGAGTTGCAAAATGAG
CTGGATGCCAAATACCCTGATGCCTCAATCAAGGTGTGGAAGTTTATGCTCGGTCGCGGCGGCGGCAAGAAAATTGAAGC
CGGTTTCAAAGGCCCAGACAGCCACGTGCTACGCCAATTGGCCGAACAAGCCAAAGCAATTATGCATAACGACCCGAACT
TGATTGCGGTGCAAGATGACTGGCGTCAACAAGTGCCGGTATTGCAACCCGTGTATTCCGCACAAGAAGCACAGCGCCTT
GGCTTAACCACGCAAGAAATCAGCGCCGCGATCGCGCAAACGCTCAATGGCCGTAATGTTGGGGTGTATCGCGAAGGCAA
TGACTTGATCCCGTTGATGGTTCGCGCACCAGAAAATGAACGCCACCACGAACGTGCGATTGAAAACAGTGAAGTGTTCA
GCGCGCAAGCTGGCCGTTACATTCCGGTGAGCCAACTGGTGGATTCGGTCGATACTGTCTATCAAGATGCCTTACTGCGC
CGTATTAACCGCATGCCGACCATCTTGGTACAAGCTGACCCAGCGCCGGGTGTGATGACGGCCGATGCGTTCAATAATGT
GCGCGAAAAAATCGAGCAGATTGAGCTACCAGCTGGCTATGAGCTGATTTGGTACGGTGAATACAAAGCCTCGAAAGACG
CCAATGAAGGTTTGGCGCTCTCCGCTCCTTATGGCTTTGCGGCGATGATTCTCGCGGTGGTGTTTATGTTTAACGCGCTG
CGTCAGCCACTCGTGATCTGGATGACCGCACCCTTTGCCGTTGTGGGTGTCACCATTGGCCTTATCGCCTTTCAAACTCC
GTTCGAGTTTATGGCGATCCTCGGCTTTTTAAGCTTGATTGGTATGATGGTGAAAAACGCGATTGTGTTGGTTGACCAAG
CGGATGCGGAAATTCGAGCAGGTAAAGAAGCTTACTTCGCGATCATTGATGCGGCGGTGAGCCGTGCACGCCCGGTTCTG
CTCGGCGCATTCACCACGATTTTAGGGGTAGCGCCTCTGCTGGTAGACCCATTCTTTAAGAGTATGGCGGTCACCATTAT
GTTTGGTTTGCTGTTTGCTACCATTCTGACCTTAGTCGTGATCCCGCTCTTCTATGCCGTGCTGTTTAGAGTGAAAGTCG
CCAAAGCATAA

Protein sequence :
MDIARYTLAKRTSVWVLIALTLIGGYISYLKLGRFEDPEFVIRQAVIVTPYPGATAQEVSDEVTDVIEGAVQALQELKEV
KSVSMQGRSEVTVEIKLEFAKSSAQLQQVWDKLRRKVADAQRQLPPGAGASIVNDDFSDVYALFYAVTGEGFSDKQLQDY
VDTLRRELVLVPGVAKAATLAEQQEAIFIEMSSERMAEFGLSVERVLQVLQKQSLVTVAGSVDAQQMRIPVIPKSNISSL
ADLTNLQVAVGSNNAVVRLGDIANISRGYTEPASMLMRYNGQRAIGFGISNVTGGNVVEMGDAVKARLAELESQRPLGMD
LHVISMQSDSVRASVANFIDNLIAAVAIVFVVLLLFMGVRSGVIIGFVLLLTVAGTLCVMLIDDIAMQRISLGALIIALG
MLVDNAIVVTDGVLVRFQQEPNADKQQVVSEVVNATKWPLLGGTVVGIFAFSAIGLSPSDMGEYAGSLFWVILYSMFLSW
VFAVTVTPMLCHDFLRVKAPTKEAKPSKLVTGYKAVLQWVLSHRVVSCAMLLGTLVAAVWGAQFIPPGFMPESQRPQFVV
DVYLPQGSDIRRTEQVVASIEKDVTQKDGITNITSFIGGGGLRFMLTYSPEARNPSYGQLLIDIDDYTKIAPLVGELQNE
LDAKYPDASIKVWKFMLGRGGGKKIEAGFKGPDSHVLRQLAEQAKAIMHNDPNLIAVQDDWRQQVPVLQPVYSAQEAQRL
GLTTQEISAAIAQTLNGRNVGVYREGNDLIPLMVRAPENERHHERAIENSEVFSAQAGRYIPVSQLVDSVDTVYQDALLR
RINRMPTILVQADPAPGVMTADAFNNVREKIEQIELPAGYELIWYGEYKASKDANEGLALSAPYGFAAMILAVVFMFNAL
RQPLVIWMTAPFAVVGVTIGLIAFQTPFEFMAILGFLSLIGMMVKNAIVLVDQADAEIRAGKEAYFAIIDAAVSRARPVL
LGAFTTILGVAPLLVDPFFKSMAVTIMFGLLFATILTLVVIPLFYAVLFRVKVAKA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 0.0 100

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
VC1757 NP_231393.1 AcrB/AcrD/AcrF family transporter BAC0425 Protein 0.0 100
VC1757 NP_231393.1 AcrB/AcrD/AcrF family transporter BAC0519 Protein 0.0 44
VC1757 NP_231393.1 AcrB/AcrD/AcrF family transporter BAC0428 Protein 0.0 43
VC1757 NP_231393.1 AcrB/AcrD/AcrF family transporter BAC0526 Protein 0.0 41