Gene Information

Name : VC1110 (VC1110)
Accession : NP_230755.1
Strain :
Genome accession: NC_002505
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1179130 - 1180437 bp
Length : 1308 bp
Strand : +
Note : 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA'

DNA sequence :
ATGCTGGATTCTAAATTACTTCGTACTGAGCTGGACGAAACAGCTGCAAAATTGGCACGTCGCGGTTTTAAACTCGACGT
GGAGACTATCCGTACTCTTGAAGAACAACGTAAGTCCATTCAAGTAGAAGTTGAGAATTTACAATCCACGCGTAACTCCA
TCTCCAAGCAAATCGGTCAACTGATGGCGTCTGGCGACAAAGCGGGCGCTGAAGCGGTTAAACAACAAATCGGCACTTTG
GGTGACGATCTGGATGCGAAAAAAGTGGAATTGGATGCGGTTATGGCGCAATTGGATGCGATCACCCAAACCGTGCCTAA
CATTCCAGACGATGCAGTGCCAAACGGTAAAGACGACAGCGAAAACGTAGAAGTTTCTCGTTGGGGAACACCAAAAACTT
ATGATTTTGAAGTAAAAGATCACGTGGATTTGGGCGAAATGGGCGACGGTCTGGATTTCGCTAGCGCAACCAAGATCACG
GGTGCGCGTTTTGTGGTGATGAAAGGTCAATTTGCTCGTTTGCACCGTGCTATCGCACAGTTCATGTTGGATCTGCACAC
CGATCAACACGGTTACACTGAGCTGTATGTACCTTACCTAGTGAACGCGGAAACGCTGTTCGGTACAGGTCAATTACCAA
AATTCGGTCAAGATCTATTCCACACTGAGCCTCTGACTGAGAAAGCCAGTGATGAAGAGCCACGCCGTCTGTCACTGATC
CCAACCGCAGAAGTGCCAGTGACCAACTTAGTGCGTGACACCATTTTGGATGAAGCTGAACTGCCTCTGAAAATGACCGC
ACACACGCCTTGTTTCCGCTCTGAGGCGGGTTCTTATGGTCGTGATACTCGCGGTCTGATCCGTATGCATCAGTTTGATA
AAGTGGAACTGGTACAAATCACTCGCCCTGAAGATTCCATGGCGGCATTGGAAGAGTTGACTGGCCATGCAGAAAAAGTT
CTGCAACTGCTGGAGCTGCCTTACCGCAAAGTGATTCTGTGTACGGGCGACATGGGCTTTGGCTCGTGCAAAACTTACGA
CTTGGAAGTTTGGGTTCCAGCGCAGAAGACGTACCGTGAAATCTCTTCTTGTTCAAACATGTGGGATTTCCAAGCGCGTC
GTATGCAAGCGCGTTTCCGCCGCAAAGGTGAGAAGAAACCTGAGTTGGTGCACACGCTGAACGGCTCTGGTCTGGCGGTG
GGTCGTACCATGGTCGCGATTTTGGAAAACTACCAAGAAGCCGATGGTCGCATTGCGATCCCTGCGGTACTGCAAAAGTA
CATGGGCGGTTTAACCCATATCGGTTAA

Protein sequence :
MLDSKLLRTELDETAAKLARRGFKLDVETIRTLEEQRKSIQVEVENLQSTRNSISKQIGQLMASGDKAGAEAVKQQIGTL
GDDLDAKKVELDAVMAQLDAITQTVPNIPDDAVPNGKDDSENVEVSRWGTPKTYDFEVKDHVDLGEMGDGLDFASATKIT
GARFVVMKGQFARLHRAIAQFMLDLHTDQHGYTELYVPYLVNAETLFGTGQLPKFGQDLFHTEPLTEKASDEEPRRLSLI
PTAEVPVTNLVRDTILDEAELPLKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVELVQITRPEDSMAALEELTGHAEKV
LQLLELPYRKVILCTGDMGFGSCKTYDLEVWVPAQKTYREISSCSNMWDFQARRMQARFRRKGEKKPELVHTLNGSGLAV
GRTMVAILENYQEADGRIAIPAVLQKYMGGLTHIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-97 54