Gene Information

Name : pyk (CPj0097)
Accession : NP_300156.1
Strain : Chlamydophila pneumoniae J138
Genome accession: NC_002491
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 124226 - 125680 bp
Length : 1455 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCACACGCACTAAAATTATTTGCACTATAGGGCCAGCAACGAATAGTCCAGAGATGTTAGCAAAACTTCTAGATGC
TGGGATGAACGTAGCAAGATTAAATTTCAGTCATGGGAGTCACGAAACTCATGGACAGGCTATTGGATTTCTCAAGGAGT
TAAGGGAGCAGAAGCGGGTTCCTTTAGCAATTATGCTAGATACTAAGGGGCCTGAAATTCGTTTAGGGAATATTCCTCAG
CCAATTTCGGTTTCTCAGGGACAAAAGCTTCGTCTGGTAAGTAGTGATATCGATGGGAGTGCTGAAGGGGGAGTGTCTCT
CTATCCTAAGGGGATATTTCCCTTTGTTCCTGAGGGTGCTGATGTTTTAATAGATGATGGCTACATTCATGCTGTTGTTG
TCTCTTCAGAGGCTGATTCTTTAGAATTAGAGTTTATGAACAGTGGCCTTCTCAAGTCTCATAAATCTTTGAGTATCCGA
GGTGTTGATGTTGCTCTTCCCTTTATGACAGAGAAAGATATTGCGGATCTTAAGTTTGGGGTAGAGCAGAATATGGATGT
GAATGCTGCATCTTTTGTGCGCTACGGTGAAGATATTGAAACTATGCGCAAGTGTTTAGCAGACTTAGGCAATCCTAAGA
TGCCCATCATTGCAAAAATAGAAAATCGTTTAGGGGTAGAAAATTTCTCTAAGATTGCCAAGCTTGCGGATGGAATTATG
ATTGCTAGAGGAGATTTAGGAATCGAGCTTTCTGTCGTTGAAGTCCCAAATTTGCAAAAGATGATGGCTAAGGTTTCTAG
AGAAACAGGTCACTTCTGTGTGACTGCAACGCAGATGCTAGAATCTATGATTCGCAATGTCTTACCTACACGAGCTGAAG
TCTCTGATATTGCCAATGCAATTTATGATGGTTCTTCAGCAGTGATGTTGTCAGGGGAAACTGCATCTGGAGCCCATCCC
GTGGCTGCCGTGAAAATCATGCGTTCTGTGATTTTAGAAACAGAAAAGAATCTCTCCCATGATTCATTCTTAAAATTAGA
CGATAGCAATAGCGCTCTTCAGGTGTCCCCCTATCTCTCAGCCATTGGATTGGCAGGCATTCAGATTGCAGAAAGGGCAG
ACGCCAAAGCTCTTATTGTTTATACAGAATCAGGAAGTTCTCCGATGTTTCTCTCTAAATATCGTCCGAAATTCCCTATC
ATTGCCGTGACTCCAAGCACTTCTGTTTACTATCGCCTAGCTTTGGAATGGGGGGTCTATCCTATGCTTACCCAGGAAAG
TGATCGCGCTGTATGGAGACATCAGGCCTGTATTTATGGCATAGAACAGGGCATTCTCTCTAATTATGATCGGATTCTTG
TGCTTAGCAGAGGAGCCTGTATGGAAGAAACAAATAATCTTACCCTGACAATAGTGAATGATATTTTGACTGGGTCGGAA
TTTCCTGAAACCTAG

Protein sequence :
MITRTKIICTIGPATNSPEMLAKLLDAGMNVARLNFSHGSHETHGQAIGFLKELREQKRVPLAIMLDTKGPEIRLGNIPQ
PISVSQGQKLRLVSSDIDGSAEGGVSLYPKGIFPFVPEGADVLIDDGYIHAVVVSSEADSLELEFMNSGLLKSHKSLSIR
GVDVALPFMTEKDIADLKFGVEQNMDVNAASFVRYGEDIETMRKCLADLGNPKMPIIAKIENRLGVENFSKIAKLADGIM
IARGDLGIELSVVEVPNLQKMMAKVSRETGHFCVTATQMLESMIRNVLPTRAEVSDIANAIYDGSSAVMLSGETASGAHP
VAAVKIMRSVILETEKNLSHDSFLKLDDSNSALQVSPYLSAIGLAGIQIAERADAKALIVYTESGSSPMFLSKYRPKFPI
IAVTPSTSVYYRLALEWGVYPMLTQESDRAVWRHQACIYGIEQGILSNYDRILVLSRGACMEETNNLTLTIVNDILTGSE
FPET

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-59 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 1e-59 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 1e-59 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-59 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk NP_300156.1 pyruvate kinase VFG0479 Protein 5e-60 41