Gene Information

Name : XF2299 (XF2299)
Accession : NP_299578.1
Strain : Xylella fastidiosa 9a5c
Genome accession: NC_002488
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2184654 - 2185427 bp
Length : 774 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGTCTCGAAATCGTGCCTTTTGTAGTTGCTATTCCCGCACGTTTTTCCGCATCACGACTGCCTGGAAAACCGCTGCG
CCTGCTTGGTGGTCGCCCACTGATTCACAGGGTAGCCGAGCGGGCACTTAGCGCAGGCGCACGGGAAGTATGGGTTGCAA
CCGACGATGTACGCATCGCTGAGGCCGTTGCTTCTCTGGACGGTGTCCACGTGGCGATGACCGCAAACACTCACCTATCC
GGAAGCGACCGCTTAGCCGAGTGCGCACGCATCGCCGGATGGGATCCTGAGATGTGCGTGGTCAACCTACAGGGCGATGA
GCCGTTCGCACCAGCGGCGGGGATTCGTGCTGTAGCGGCATTGCTGCATCACAGCAATGCCGACATGGCAACGCTCGCAA
CGACCATTGACAAGAGCGAAGACCTGTTCAACCCGAACATCGTCAAATTGGTGTGCAATGCACATGGAGAAGCGTTGTAC
TTCAGCCGTGCCCCGATCCCATGGAATCGGGATACCTTCGCCACAACGCCTGAACCAACGCCATTGGGTCCGTGGCTACG
CCACATCGGTCTCTATGCCTGCAACGCTGGGTTCCTGCAACGCTTCACCACGATGCAACCGGGGACCTTGGAGCAGATTG
AATCGTTGGAACAACTGCGTGTGCTGGAAGCAGGACATCGGATCGCGGTCAGGATCACTCCGGAACATTTCCCGCCCGGT
ATCGATACCCCAGAAGACTTAGCCAGAGCCGAGAAGGCATTGGAGGATGTATGA

Protein sequence : 
MSLEIVPFVVAIPARFSASRLPGKPLRLLGGRPLIHRVAERALSAGAREVWVATDDVRIAEAVASLDGVHVAMTANTHLS
GSDRLAECARIAGWDPEMCVVNLQGDEPFAPAAGIRAVAALLHHSNADMATLATTIDKSEDLFNPNIVKLVCNAHGEALY
FSRAPIPWNRDTFATTPEPTPLGPWLRHIGLYACNAGFLQRFTTMQPGTLEQIESLEQLRVLEAGHRIAVRITPEHFPPG
IDTPEDLARAEKALEDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-26 43
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-26 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 3e-26 42