Gene Information

Name : leuS (CP0618)
Accession : NP_445160.1
Strain : Chlamydophila pneumoniae AR39
Genome accession: NC_002179
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 643306 - 645768 bp
Length : 2463 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCGATATGACCCCAACTTAATAGAAAAAAAATGGCAACAATTTTGGAAAGAACATCGAAGCTTTCAAGCAAATGAAGA
CGAGGATAAAGTAAAATATTATGTTTTAGACATGTTCCCTTATCCTTCAGGAGCAGGTCTACATGTAGGCCACCTTATTG
GCTATACAGCGACAGATATTGTTGCGAGATATAAAAGAGCACGGGGATTCTCAGTTCTTCATCCTATGGGCTGGGATAGC
TTTGGTTTGCCCGCAGAACAATATGCGATTCGGACAGGAACCCATCCTAAAGTCACGACCCAGAAGAATATCGCTAATTT
TAAAAAACAGCTCTCCGCTATGGGATTTTCGTATGATGAAGGACGAGAATTTGCTACGAGTGATCCCGACTATTATCATT
GGACTCAGAAACTTTTCCTTTTTCTTTATGATCAAGGACTCGCCTATATGGCCGACATGGCAGTGAACTACTGTCCAGAA
CTTGGTACCGTATTATCGAATGAAGAAGTTGAAAATGGATTCTCAATAGAAGGGGGATATCCTGTAGAGCGGAAAATGCT
TCGTCAGTGGATTCTCAAAATCACAGCATATGCCGATAAGTTATTAGAAGGTCTCGATGCCCTAGATTGGCCCGAAAATG
TAAAGCAGTTACAGAAAAATTGGATAGGGAAATCTGAAGGGGCTCTCGTAACATTTCATTTGACGCAAGAGGGCAGTCTA
GAAGCCTTCACTACCCGCCTAGACACTTTATTAGGGGTGAGTTTCTTAGTGATTGCTCCTGAGCACCCAGATTTAGATTC
TATAGTGAGTGAAGAGCAAAGAGACGAAGTCACAGCCTATGTACAAGAGAGTCTCAGGAAAAGTGAACGAGATCGCATTA
GCTCTGTTAAGACAAAAACAGGGGTCTTTACAGGAAACTATGCCAAGCACCCCATTACAGGGAACCTTTTACCTGTTTGG
ATTTCAGATTATGTCGTCTTAGGCTATGGCACAGGCGTAGTTATGGGAGTCCCAGCGCATGACGAGAGAGATCGAGAGTT
TGCTGAAATGTTTTCTCTTCCGATTCATGAGGTGATTGATGATAACGGGGTTTGTATTCATAGCAATTACAACGACTTTT
GTCTTAATGGCTTGTCTGGGCAAGAAGCTAAAGATTATGTAATCAACTACCTGGAGATGCGTTCTCTCGGAAGAGCTAAG
ACTATGTACAGGCTGCGAGACTGGCTCTTCTCTAGACAGAGATATTGGGGAGAGCCTATCCCCATCATTCATTTTGAAGA
TGGAACGCACCGTCCTTTAGAAGATGATGAGCTGCCTCTTCTCCCTCCGAATATTGATGACTATCGTCCCGAAGGATTCG
GTCAGGGTCCTTTAGCGAAGGCTCAAGATTGGGTGCATATCTACGACGAGAAGACAGGTAGACCAGGATGTAGAGAGACT
TATACTATGCCACAGTGGGCAGGCTCTTGCTGGTATTATCTTCGTTTCTGTGATGCACACAACTCTCAGTTGCCTTGGAG
TAAAGAAAAAGAAAGCTATTGGATGCCTGTAGATCTTTACATTGGAGGTGCAGAACACGCTGTTCTTCATCTTCTTTACT
CGAGATTTTGGCATCGAGTCTTCTATGACGCGGGTCTTGTCTCAACACCAGAACCTTTTAAGAAACTGATCAACCAGGGA
CTTGTGTTAGCCTCTTCATACCGAATTCCTGGTAAGGGATACGTAAGCATAGAAGACGTTAGGGAAGAAAATGGAACGTG
GATCTCAACTTGTGGAGAGATTGTGGAAGTTAGACAAGAGAAAATGTCTAAATCGAAACTCAATGGTGTGGATCCTCAGG
TTTTGATTGAAGAGTATGGTGCAGATGCCTTACGTATGTACGCTATGTTTTCGGGACCCTTGGATAAAAATAAAACCTGG
TCCAATGAAGGTGTTGGGGGGTGCCGTCGTTTCCTAAATCGTTTTTATGATTTGGTGACTTCGTCAGAGGTTCAAGATAT
AGAAGACCGTGACGGGCTGGTTCTCGCTCACAAATTGGTGTTTAGGATTACAGAACATATTGAAAAAATGTCTTTGAATA
CCATACCGTCTTCATTTATGGAATTTCTGAACGATTTTTCAAAGCTTCCAGTCTATTCTAAACGTGCCTTGTCTATGGCT
GTTCGTGTATTGGAGCCTATAGCTCCGCATATCAGCGAAGAGTTATGGGTTATATTGGGAAACCCACCAGGGATTGATCA
AGCAGCATGGCCTCAAATAGACGAGAGTTACCTAGTTGCTCAAACTGTGACTTTTGTTGTTCAGGTTAATGGGAAGTTAC
GAGGACGTCTCGAGGTAGCCAAAGAAGCTCCTAAAGAAGAAGTTTTATCTTTGTCTCGAAGTGTAGTTGCAAAGTATCTA
GAGAACGCTCAAATACGAAAAGAAATTTATGTTCCTAATAAACTAGTGAATTTTGTCCTATGA

Protein sequence :
MRYDPNLIEKKWQQFWKEHRSFQANEDEDKVKYYVLDMFPYPSGAGLHVGHLIGYTATDIVARYKRARGFSVLHPMGWDS
FGLPAEQYAIRTGTHPKVTTQKNIANFKKQLSAMGFSYDEGREFATSDPDYYHWTQKLFLFLYDQGLAYMADMAVNYCPE
LGTVLSNEEVENGFSIEGGYPVERKMLRQWILKITAYADKLLEGLDALDWPENVKQLQKNWIGKSEGALVTFHLTQEGSL
EAFTTRLDTLLGVSFLVIAPEHPDLDSIVSEEQRDEVTAYVQESLRKSERDRISSVKTKTGVFTGNYAKHPITGNLLPVW
ISDYVVLGYGTGVVMGVPAHDERDREFAEMFSLPIHEVIDDNGVCIHSNYNDFCLNGLSGQEAKDYVINYLEMRSLGRAK
TMYRLRDWLFSRQRYWGEPIPIIHFEDGTHRPLEDDELPLLPPNIDDYRPEGFGQGPLAKAQDWVHIYDEKTGRPGCRET
YTMPQWAGSCWYYLRFCDAHNSQLPWSKEKESYWMPVDLYIGGAEHAVLHLLYSRFWHRVFYDAGLVSTPEPFKKLINQG
LVLASSYRIPGKGYVSIEDVREENGTWISTCGEIVEVRQEKMSKSKLNGVDPQVLIEEYGADALRMYAMFSGPLDKNKTW
SNEGVGGCRRFLNRFYDLVTSSEVQDIEDRDGLVLAHKLVFRITEHIEKMSLNTIPSSFMEFLNDFSKLPVYSKRALSMA
VRVLEPIAPHISEELWVILGNPPGIDQAAWPQIDESYLVAQTVTFVVQVNGKLRGRLEVAKEAPKEEVLSLSRSVVAKYL
ENAQIRKEIYVPNKLVNFVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 50